Table 3_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.doc حسب Meizhi Liu (21898892)

"…Frontier analysis revealed significant gaps between current burdens and achievable benchmarks, particularly in high-SDI regions, while some low-SDI regions demonstrated effective management despite limited resources. …"

DataSheet2_Screening of active components of melastoma dodecandrum lour. against diabetic osteoporosis using cell membrane chromatography-mass spectrometry.pdf حسب Xiaoqin Zhang (517854)

"…Cell experiments further validated the activity of the characteristic component isovitexin.</p>Results<p>MD significantly improved cell viability in AGEs-damaged osteoblasts, enhanced ALP, SOD, CAT, and GPx activities, reduced MDA levels, increased OCN and RUNX2 protein expression, and decreased TNF-α mRNA and RAGE protein expression. …"

Image 6_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.tiff حسب Tien Le (634791)

"…Crim1 encodes a type I transmembrane protein that is expressed at the cell membrane of lens epithelial and fiber cells at the stage of lens pit formation. Decreased Crim1 expression in the mouse reduced the number of lens epithelial cells and caused defective adhesion between lens epithelial cells and between the epithelial and fiber cells.…"

Table 3_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.docx حسب Songqin Chen (9625886)

"…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…"

Data Sheet 2_Burden of NASH related liver cancer from 1990 to 2021 at the global, regional, and national levels.pdf حسب Shuang Li (146392)

"…At the national level, ASRs consistently decreased with higher SDI.</p>Conclusion<p>This study highlights the substantial burden of NRLC at global, regional, and national levels. …"

Supplementary Material for: Dorsal Column Spinal Cord Stimulation Attenuates Brain-Spine Connectivity through Locomotion and Visuospatial-Specific Area Activation in Progressive Fr... حسب Zemmar A. (11259339)

"…Introduction: Freezing of gait (FOG) is a clinical phenomenon with major life impairments and significant reduction in quality of life for affected patients. …"

Table 2_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.docx حسب Ilmari Pyykkö (2855153)

"…The frequency and duration of vertigo attacks generally decreased over time, with attacks becoming shorter and less severe as the disease progressed. …"

Image2_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.JPEG حسب Jacob Raiten (20021262)

"…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4⁺ and CD8⁺ T cells in implanted limb muscles of mouse models. …"

Table2_Predicting candidate miRNAs for targeting begomovirus to induce sequence-specific gene silencing in chilli plants.xlsx حسب Vineeta Pandey (10043698)

"…Chilli cultivars infected with begomovirus have suffered significant decreases in biomass output, negatively impacting their economic characteristics. …"

Data Sheet 2_BNIP3-mediated mitophagy aggravates placental injury in preeclampsia via NLRP1 inflammasome.pdf حسب Man Zhao (314232)

"…Furthermore, silencing BNIP3 leads to a significant reduction in mitochondrial damage and mtROS production. …"

Table1_Body composition and perceived stress levels in transgender individuals after one year of gender affirming hormone therapy.docx حسب Chiara Ceolin (19553155)

"…Introduction<p>Higher stress levels are linked to increased body fat and decreased bone density, effects that can be exacerbated by lifestyle choices. …"

Reduced Aqueous Retinol Binding Protein 3 Concentration is Associated with Diabetic Macular Edema and Progression of Diabetic Retinopathy حسب Tanvi Chokshi (12970453)

"…There was no significant difference between aqueous RBP3 levels in those with type 1 or type 2 diabetes. …"

Table 3_Dihydromyricetin attenuates age-related macular degeneration: pharmacological effects and exploration of putative targets.xlsx حسب Hongyu Zhou (352858)

"…Western blot analysis further confirmed DHM-mediated suppression of apoptosis through regulation of p53, Bax, cleaved caspase-3, and Bcl-2 expression. High-dose DHM significantly attenuated retinal thinning (10.7% reduction), decreased pigment loss, and ameliorated structural disorganization in the outer nuclear layer (ONL). …"

Image 3_IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy.jpeg حسب Dylan Krajewski (5881880)

"…IL-10-depleted WT mice exhibited a significant attenuation in MC-mediated responses to OVA challenge. …"

Supplementary file 1_From lockdown to recovery: changing patterns of viral infection severity in a pediatric cohort with asthma.docx حسب Cassidy Jones (22301638)

"…RV/EV was the most common virus during all periods. Viral incidence decreased during NPIs but rebounded post-NPI with unusual seasonality. mWHO OSI scores declined over time (pre-NPI: 2.98; NPI: 2.49; post-NPI: 2.28), with significant reductions in hospitalizations, PICU admissions, and oxygen use (p < 0.0001). …"

Amplifying key words’ intensity promotes memory (Liu et al., 2025) حسب Zhenxu Liu (1372929)

"…Heart rate and skin conductance level of the subjects decreased with amplification of key word intensity in the 9-dB group, which indicated that this promoted the memory effect by enhancing attention.…"

Data Sheet 1_Guanxinning attenuates diabetic myocardial ischemia–reperfusion injury by targeting oral Fusobacterium nucleatum and modulating PTEN signaling.docx حسب Yiwen Li (354034)

"…</p>Results<p>GXN treatment significantly reduced myocardial injury in diabetic mice and decreased oral F. nucleatum abundance, although its effects on other gut microbiota taxa were variable. …"

Data Sheet 1_Efficacy of different pharmaceutical forms of Curcuma longa or curcumin in reducing oral mucositis severity and incidence in cancer patients: a systematic review and m... حسب Pedro de Padua G. Amatto (20981201)

"…The pooled analysis showed significant reductions in WHO scores and oral pain compared to placebo. …"

Table 1_Hemerocallis citrina Baroni leaf total phenol alleviates depressive-like behaviors via modulating “microbiota-gut-brain” axis in chronic unpredictable mild stress -induced... حسب Yanping Wang (275956)

"…Additionally, HLTP reversed 63 CUMS-induced abnormal serum metabolites, primarily affecting tryptophan metabolism, niacin and nicotinamide metabolism, and porphyrin metabolism. Significant correlations were observed among gut microbial composition, serum metabolite levels, biochemical indices, and behavioral outcomes.…"

Table 3_Rapid reshaping of the soil microbiome and metabolome during short-term flooding and draining in rice.xlsx حسب Yanyao Lu (22163632)

"…The results revealed that S-PPO, S-POD, and S-CAT decreased with prolonged drainage time, whereas the soil redox potential (Eh-mV) and POD increased. …"