Efficacy of Low-Dose Naltrexone in Treating Patients with Fibromyalgia: systematic Review and Meta-Analysis by Abiodun Ologunowa (21343002)

“…In the LDN group, the Standardized Mean Difference (SMD) for pain decreased by 1.03 (95% confidence interval (CI): −1.25, −0.80; I² = 25%), and fibromyalgia symptom severity decreased by 1.02 (95% CI: −1.35, −0.69; I² = 52%) post-LDN treatment compared to the baseline. …”

SEAwise Report on improved predictive models of recruitment under different habitat scenarios and incorporating experimental results by Paco Melià (162862)

“…Projections show no relevant changes in herring recruitment under RCP4.5 and a decreasing trend under RCP8.5. Plaice recruitment would decline slightly under RCP8.5 and increase under RCP4.5, but from a lower level than RCP8.5. …”

Table 1_Integrated gut microbiota and metabolomic profiling reveals key associations between amino acid levels and gut microbial composition in patients with obesity.docx by Musen Qi (22489075)

“…Metabolomic analysis revealed that in patients with obesity, the abundance of carnosine (log2FC = 1.16, FDR = 0.0016, VIP = 0.707), creatinine (log2FC = 0.21, FDR = 0.0009, VIP = 2.02), and cystine (log2FC = 0.55, FDR = 0.009, VIP = 1.47) was significantly increased compared with that in the controls; in contrast, that of ornithine (log2FC = −0.59, FDR = 0.0009, VIP = 1.19), citrulline (log2FC = −0.59, FDR = 0.0003, VIP = 0.707), glycine (log2FC = −0.54, FDR = 0.0003, VIP = 1.41), and serine (log2FC = −0.38, FDR = 0.0019, VIP = 1.62) was significantly decreased. …”

PRMT5 isoforms during zebrafish developmental stages by Zain Zakaria (20354028)

“…Remarkably, despite the lack of any significant change in prmt5 mRNA levels between 18 and 72 hpf, Prmt5 protein expression showed dynamic changes at 18 and 72 hpf, which were accompanied by a change in mobility of Prmt5 protein at 72 hpf compared to other developmental stages.…”

Flow cytometry by Tingting LIAO (21775841)

“…Flow cytometry results showed that compared with normal cells, there was no significant difference in apoptosis rate after transfection of mimics NC and inhibitor NC, but significantly increased apoptosis rate after transfection of miR-126-3p inhibitor and significantly decreased apoptosis rate after transfection of miR-126-3p inhibitor.…”

Impacts of winter climate change on northern forest understory carbon dioxide exchange determined by reindeer grazing by Noora Kantola (14263490)

“…To understand how reindeer grazing, coupled with changes in snow depth affects CO₂ exchange, we used recent snow treatments (ambient, reduced, and increased snow depth) combined with 25- and 55-year-old reindeer exclusions and the adjacent grazed areas in boreal and subarctic Scots pine forests that are main winter pastures for reindeer/caribou and cover a significant portion of boreal and subarctic landscapes. …”

Data Sheet 1_Crop rotation complexity affects soil properties shaping antibiotic resistance gene types and resistance mechanisms.docx by Rong Hu (153724)

“…Our findings revealed that soil properties varied significantly with crop rotation regime and complexity. …”

Data Sheet 1_The co-occurrence patterns and assembly mechanisms of microeukaryotic communities in geothermal ecosystems of the Qinghai-Tibet Plateau.docx by Bingjie Yan (10742991)

“…The results show that with increasing temperature, the network stability of microeukaryotic communities in sediments significantly improved, while the stability in water communities decreased. …”

Riboflavin inhibits growth and reduces virulence of <i>Cryptococcus neoformans in vitro</i> by membrane disruption and excessive accumulation of reactive oxygen species and exhibit... by Jian Huang (7250)

“…Finally, in mouse models of intranasal and intravenous infection, RF treatment significantly reduced the fungal burden in multiple organs, reduced lung and brain damage, and decreased the levels of plasma interferon (IFN)-γ, tumor necrosis factor (TNF)-α, and interleukin (IL)-4 in the early stage of infection. …”

Summary of this study. by Satoshi Hara (539722)

“…The numbers in parentheses indicate the reference numbers. Panels showing significant differences are highlighted. The arrows indicate increased or decreased. …”

hsa-miR-144-3p and hsa-miR-4262 are exosomal biomarkers and function as tumor suppressors in HCMV positive brain tumor by Muhammad Shahbaz Haris (13918249)

“…Data analysis showed significant decreased levels of <i>hsa-miR-144-3p</i> (p < 0.0001) and <i>hsa-miR-4262</i> (p < 0.0001) in brain tumor patients compared to controls. …”

Pilot study on the impact of HIFU treatment on miRNA profiles in vaginal secretions of uterine fibroids and adenomyosis patients by Wei-Chun Chen (276732)

“…Notably, hsa-miR-7977, hsa-miR-155-5p, hsa-miR-191-5p, and hsa-miR-223-3p showed significant changes in fibroid cases, except in low-energy treatments. hsa-miR-7977 consistently decreased post-treatment, while hsa-miR-155-5p decreased in the least efficient cases. …”

Supplementary file 1_Burden of urogenital congenital anomalies: findings from the global burden of disease study 2021.docx by Yiwei Yue (22307683)

“…Regionally, Southern Sub-Saharan Africa exhibited the highest prevalence, while Oceania and East Asia showed significant increases and decreases, respectively. Decomposition analysis of change in prevalence indicated that, globally, population contributed the most to changes in prevalence, followed by aging and epidemiological change. …”

Supplementary file 2_Burden of urogenital congenital anomalies: findings from the global burden of disease study 2021.pdf by Yiwei Yue (22307683)

“…Regionally, Southern Sub-Saharan Africa exhibited the highest prevalence, while Oceania and East Asia showed significant increases and decreases, respectively. Decomposition analysis of change in prevalence indicated that, globally, population contributed the most to changes in prevalence, followed by aging and epidemiological change. …”

Table 2_Prevalence of pathogens from clinical samples associated with porcine respiratory and digestive diseases in South Korea from 2021 to 2023.docx by Hye-young Wang (8786045)

“…The trends in 3-year prevalence showed no significant changes, but in 2023, viral infections (e.g., PRRSV, Rotavirus, porcine epidemic diarrhea virus, etc.) decreased and bacterial infections (e.g., Mycoplasma hyopneumoniae (MH), Pasteurella multocida (PM), Haemophilus parasuis (HP), Salmonella spp., Lawsonia intracellularis, and Brachyspira hyodysenteriae) slightly increased (χ² = 11.36, P < 0.001). …”

Table 1_Prevalence of pathogens from clinical samples associated with porcine respiratory and digestive diseases in South Korea from 2021 to 2023.docx by Hye-young Wang (8786045)

“…The trends in 3-year prevalence showed no significant changes, but in 2023, viral infections (e.g., PRRSV, Rotavirus, porcine epidemic diarrhea virus, etc.) decreased and bacterial infections (e.g., Mycoplasma hyopneumoniae (MH), Pasteurella multocida (PM), Haemophilus parasuis (HP), Salmonella spp., Lawsonia intracellularis, and Brachyspira hyodysenteriae) slightly increased (χ² = 11.36, P < 0.001). …”

Additional file 1 of Whole genome sequencing of the pulmonary microbiome in interstitial lung disease subtypes by Kristel S. Knudsen (10535406)

“…Every red dot on the plot represents differentially abundant species with increased significance noted towards the top of the plot. Grey dot: not significant…”

GABA and glutamate are required for light avoidance. by Kenichi Nakayama (2354653)

“…<i>Ppa-unc-25</i> and <i>Ppa-eat-4</i> mutants exhibit decreased light avoidance. One-way ANOVA Dunnett’s multiple comparison tests, compared with wild type. n.s = not significant, *<i>P</i> < 0.05, ****<i>P</i> < 0.0001.…”

Additional file 2 of Whole genome sequencing of the pulmonary microbiome in interstitial lung disease subtypes by Kristel S. Knudsen (10535406)

“…Every red dot on the plot represents differentially abundant species with increased significance noted towards the top of the plot. Grey dot: not significant…”

Impact of moderate-to-severe ulcerative colitis and Crohn’s disease on sexual activity: United States and European patient perspectives from the communicating needs and features of... by Marla C. Dubinsky (10978320)

“…Among patients with UC, a significantly greater proportion of female patients reported altered sexual activity due to their disease. …”