Image 1_Identification and verification of autophagy-related gene signatures and their association with immune infiltration and drug responsiveness in epilepsy.tif by Han-han He (20594477)

“…The immune infiltration analysis showed that there was a significantly increased abundance of macrophages and a decreased abundance of CD4 and CD8 T cells, including Tr1, nTreg, Tfh, CD8 naïve, cytotoxic T cells and effector memory T cells in the epilepsy group. …”

Multicomponent physical exercise program among community-dwelling older adults who are users of home care services: a quasi-experimental pilot study by Aida Ruiz-Fernández (22822586)

“…Group-by-time analyses suggested improvements in the MPEP group for the Short Physical Performance Battery (η²ₚ=0.154) and Fried Frailty Scale (η²ₚ=0.164). Frailty decreased on both scales (OR = 0.142 and 0.125). No further significant effects were observed.…”

Table 1_Dietary quercetagetin attenuates H2O2-induced oxidative damage and preserves meat quality in broilers by modulating redox status and Nrf2/ferroptosis signaling pathway.docx by Wenyue Hu (799025)

“…Meanwhile, the addition of QG to the diet increased the mRNA expressions of Nrf2 and TFR1, showing no significant difference from those of the control group. …”

Data Sheet 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.docx by Lina Ouologuem (22489549)

“…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Image 1_Species-level taxonomic characterization of gut microbiota in HIV-infected individuals.pdf by Jiali Chen (5696)

“…We recruited 114 individuals in the PWH group and 58 individuals in the HC group, from whom fecal samples were collected for 16S rRNA gene sequencing of the V3–V4 region. Significant differences in α diversity and β diversity (p-values < 0.05) were observed between the two groups. …”

Data_Sheet_2_Safety and efficacy of plasmapheresis in treatment of acute fatty liver of pregnancy—a systematic review and meta-analysis.docx by Sujata Siwatch (19867233)

“…Biochemical parameter analysis demonstrated significant improvement post-PP/PE treatment, including decreased bilirubin (MD: 8.30, 95% CI: 6.75 to 9.84), AST (MD: 107.25, 95% CI: 52.45 to 162.06), ALT (MD: 111.08, 95% CI: 27.18 to 194.97), creatinine (MD: 1.66, 95% CI: 1.39 to 1.93), and Prothrombin time (MD: 5.08, 95% CI: 2.93 to 7.22).…”

Image 5_Species-level taxonomic characterization of gut microbiota in HIV-infected individuals.pdf by Jiali Chen (5696)

“…We recruited 114 individuals in the PWH group and 58 individuals in the HC group, from whom fecal samples were collected for 16S rRNA gene sequencing of the V3–V4 region. Significant differences in α diversity and β diversity (p-values < 0.05) were observed between the two groups. …”

Image_2_Study of epirubicin sustained–release chemoablation in tumor suppression and tumor microenvironment remodeling.jpeg by Liangliang Meng (9500122)

“…On day 4 after local injection of the EPI gel, the expression of PD-L1 in abscopal tumors was upregulated, while the expression of PD-L1 in bilateral tumors in mice was significantly reduced after anti-PD-L1 treatment. The proportion of CD3⁺CD8⁺PD-1⁺ cells in the tumor and circulating blood in the EPI-GEL/PD-L1 group was decreased compared with that in the EPI-GEL (single injection of epirubicin) group.…”

Table 1_MIKC-type MADS-box transcription factor OsMADS31 positively regulates salinity tolerance in rice.xlsx by Xiaolin Yin (359202)

“…Conversely, compared with WT plants, 3,3’-diaminobenzidine (DAB) and nitroblue tetrazolium (NBT) staining intensities as well as malondialdehyde (MDA) content were significantly higher in osmads31 mutants and significantly lower in OE lines. …”

Table 1_Coffee consumption as a double-edged sword for serum lipid profile: findings from NHANES 2005–2020.docx by Chaoyue Mo (21684056)

“…Although these changes were statistically significant, their clinical relevance may vary depending on individual cardiovascular risk profiles.…”

Image 6_Species-level taxonomic characterization of gut microbiota in HIV-infected individuals.pdf by Jiali Chen (5696)

“…We recruited 114 individuals in the PWH group and 58 individuals in the HC group, from whom fecal samples were collected for 16S rRNA gene sequencing of the V3–V4 region. Significant differences in α diversity and β diversity (p-values < 0.05) were observed between the two groups. …”

Image 2_Kaixin San Jiawei granule improves cognitive function and alleviates neuronal damage in Alzheimer’s disease via multi-component and multi-target mechanisms.tif by Wei Liu (20030)

“…</p>Results<p>In vivo, KSG significantly alleviated scopolamine-induced cognitive deficits in mice. …”

Supplementary file 1_Negative associations between macronutrient quality index and lung cancer incidence and mortality: results from the prostate, lung, colorectal, and ovarian can... by Dazhan Feng (22286776)

“…Our results demonstrate a distinct, statistically significant inverse association between a higher MQI and both a reduced incidence (HR Q4 vs. …”

Table 3_The relationship between the ratio of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol (NHHR) and both MASLD and advanced liver fibrosis: ev... by Juyi Li (8996117)

“…Elevated NHHR levels in the Q2 and Q3 groups remained significantly linked to a decreased risk of advanced liver fibrosis, with odds ratios of 0.61 (95% CI 0.40–0.94, P = 0.03) and 0.64 (95% CI 0.47–0.89, P = 0.01), respectively. …”

Data Sheet 1_Elocalcitol, a fluorinated vitamin D derivative, prevents high-fat diet-induced obesity via SCAP downregulation and miR-146a-associated mechanisms.pdf by Monika Jürgenson (14030901)

“…</p>Results<p>It was demonstrated that co-administration of elocalcitol in the doses 15 ug/kg (i.p.) twice a week for 16 weeks prevented body weight gain by approximately 15%. The significant retardation in the body weight gain was observed already on the second week of elocalcitol treatment. …”

Data Sheet 2_Assessing the disease burden of lower respiratory infections attributable to particulate matter pollution: trends from 1990 to 2021 and projections for 2022-2050.pdf by Erman Wu (19021269)

“…Children under 5 years of age group still accounted for the most PMP-related deaths, with the number decreasing from 851,458 (95% UI: 211,026 to 1,363,810) in 1990 to 201,078 (95% UI:61,817 to 337,232). …”

Video 4_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

Data Sheet 1_Different interventions in preventing sufentanil-induced cough: a systematic review and network meta-analysis.pdf by Hao Liu (12832)

“…Pairwise meta-analysis results indicate that the intervention group significantly decreases the overall incidence of SIC (7.6% vs. 34.8%; OR 0.13; 95% CI 0.09 to 0.18; P < 0.0001; I² = 53.0%), the incidence of mild SIC (4.0% vs. 13.0%; OR 0.28; 95% CI 0.22 to 0.35; P = 0.369; I² = 5.7%), and the incidence of moderate to severe SIC (3.4% vs. 21.7%; OR 0.13; 95% CI 0.10 to 0.16; P = 0.040; I² = 30.6%). …”

Table 1_Oral supplementation with Lactobacillus fermentum MC018 improves intestinal health, immune response, and growth performance of Zi geese infected with Escherichia coli XH197... by Yang Li (7082)

“…Introduction<p>Escherichia coli infection causes severe diarrhea, decreases growth performance, and increases mortality of poultry, which imposes a significant economic burden on the poultry industry and severely limits its growth.…”

Data Sheet 1_Identification of potential biomarkers for lung adenocarcinoma: a study based on bioinformatics analysis combined with validation experiments.zip by Chuchu Zhang (2562154)

“…Meanwhile, TGFBR2 expression was decreased in LUAD group through immunohistochemistry. …”