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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant changes » significant challenge (Expand Search)
significant based » significant cause (Expand Search), significant barrier (Expand Search), significant burden (Expand Search)
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19381
Data_Sheet_1_Association of systemic immune-inflammation index with malnutrition among Chinese hospitalized patients: a nationwide, multicenter, cross-sectional study.docx
Published 2024“…Both lower and higher SII levels (either continuous or categorical variable) were significantly associated with an increased risk of malnutrition.…”
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19382
Table 1_Danggui Buxue Decoction attenuates 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone—induced lung cancer growth in A/J mice by suppressing HIF-1α/VEGF-mediated angiogenesis.do...
Published 2025“…By week 20, progressive multifocal opacities emerged alongside reduced pulmonary artery flow, impaired lung function, elevated TNF-α/VEGF, and decreased WBC, lymphocytes, and platelets. Compared to untreated controls, 10-week DBD treatment significantly suppressed lung tumor growth, reduced lesion microvessel density, downregulated HIF-1α and VEGF expression, and ameliorated hematological dysregulation.…”
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19383
Table 1_Effect of compound kushen injection on immune function in patients with colorectal cancer: a systematic review and meta-analysis.docx
Published 2025“…Chemotherapy and radiotherapy remain cornerstone treatments; however, they often lead to significant immune suppression and an increased risk of infection. …”
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19384
Supporting data for <b>Drivers, Composition and Potential for Innovative Vector Control Approaches in the mosquito</b>
Published 2025“…While most Bacteria and Viruses studied showed correlations with decreased immune gene expression, some, such as Doliuvirus or Siphonobacter, were associated with increased immune gene expression. …”
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19385
Uncovering the mechanistic basis of <i>Rheum palmatum</i> L. (rhubarb) in the treatment of chronic kidney disease: an integrative approach using network pharmacology, molecular doc...
Published 2025“…MR analysis demonstrated a statistically significant causal association between TNF and CKD (OR = 1.02, <i>p</i> < 0.05), with positive trends for IL6 and CASP3. …”
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19386
Image 2_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpeg
Published 2025“…Isolated lung trNK cells of the ALI mice exhibited reduced CD107a and NKp46 markers and cytotoxicity potentials and were correlated through significantly 2.1-fold higher levels of PD-1 and diminished VDR expressions as compared to naïve mice. …”
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19387
Image 3_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpeg
Published 2025“…Isolated lung trNK cells of the ALI mice exhibited reduced CD107a and NKp46 markers and cytotoxicity potentials and were correlated through significantly 2.1-fold higher levels of PD-1 and diminished VDR expressions as compared to naïve mice. …”
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19388
Table 1_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.docx
Published 2025“…Isolated lung trNK cells of the ALI mice exhibited reduced CD107a and NKp46 markers and cytotoxicity potentials and were correlated through significantly 2.1-fold higher levels of PD-1 and diminished VDR expressions as compared to naïve mice. …”
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19389
Table1_Clinical efficacy of Fufang Yinhua Jiedu (FFYH) granules in mild COVID-19 and its anti-SARS-CoV-2 mechanism by blocking autophagy through inhibiting the AKT/mTOR signaling p...
Published 2024“…</p>Conclusion<p>Our results indicate that FFYH not only has good anti-viral activity against SARS-CoV-2 but also has significant efficacy against COVID-19, indicating that FFYH may be a novel complementary option for treating COVID-19.…”
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19390
Table 1_Studies on fatty acids and microbiota characterization of the gastrointestinal tract of Tianzhu white yaks.docx
Published 2025“…Introduction<p>The gut microbiota significantly influences the host’s production performance and health status, with different gastrointestinal tissues exhibiting functional diversity reflected in their microbial diversity.…”
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19391
AjMLKL is involved in 10<sup>8</sup> CFU/mL AJ01 induced lytic coelomocyte death independent on its phosphorylation.
Published 2025“…Coelomocyte viability was significantly increased (L), and coelomocytes plasma membrane disruption (M) and the percentage of Annexin V+/PI+ coelomocytes significantly decreased (N). …”
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19392
Data Sheet 1_Workplace harassment is associated with differences in personality traits, coping strategies and work ability: cross sectional study among healthcare professionals.pdf
Published 2025“…Exposure to WPH is associated with decreased work ability. Low rate of formal reporting reveals systemic gaps in institutional responses. …”
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19393
Table2_Clinical efficacy of Fufang Yinhua Jiedu (FFYH) granules in mild COVID-19 and its anti-SARS-CoV-2 mechanism by blocking autophagy through inhibiting the AKT/mTOR signaling p...
Published 2024“…</p>Conclusion<p>Our results indicate that FFYH not only has good anti-viral activity against SARS-CoV-2 but also has significant efficacy against COVID-19, indicating that FFYH may be a novel complementary option for treating COVID-19.…”
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19394
Effects of extracorporeal shock wave therapy on motor function in patients with cerebral palsy: a systematic review and meta-analysis
Published 2025“…In addition, spasticity significantly decreases, particularly with focused ESWT or ESWT targeting the upper limbs.…”
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19395
SNAP-25 (1-197) binds to syntaxin-1A, and the interaction is enhanced by Ser187 phosphorylation.
Published 2025“…<b>(C and D)</b> PMA treatment further decreases neurotransmitter release when a low level of SNAP-25 cleavage is present. …”
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19396
The role of SLMO in the PSS/PISD pathway.
Published 2024“…(C) SLMO overexpression failed to reverse decreased mitochondrial size from <i>pisd</i><sup><i>RNAi</i></sup> lines. …”
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19397
Image 1_Restoring natural killer cell activity in lung injury with 1,25-hydroxy vitamin D3: a promising therapeutic approach.jpg
Published 2025“…Isolated lung trNK cells of the ALI mice exhibited reduced CD107a and NKp46 markers and cytotoxicity potentials and were correlated through significantly 2.1-fold higher levels of PD-1 and diminished VDR expressions as compared to naïve mice. …”
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19398
Data Sheet 1_Preclinical evidence and potential mechanisms of tanshinone ⅡA on cognitive function in animal models of Alzheimer’s disease: a systematic review and meta-analysis.doc...
Published 2025“…Additionally, it exhibited antiapoptotic effects by increasing the B-cell lymphoma-2/Bcl-2-associated X protein (Bcl-2/Bax) ratio and decreasing Caspase-3 expression. Moreover, treatment improved neuronal/synaptic plasticity by upregulating postsynaptic density-95 (PSD-95) and brain-derived neurotrophic factor (BDNF) levels.…”
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19399
Data Sheet 1_Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.docx
Published 2025“…The serum metabolic profile of IAV patients was significantly changed, and the purine metabolism was destroyed. …”
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19400
Image 2_Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.jpeg
Published 2025“…The serum metabolic profile of IAV patients was significantly changed, and the purine metabolism was destroyed. …”