Supplementary Material for: From childhood to adolescence: Long-term trends in severe obesity in German youth (2002–2023) by figshare admin karger (2628495)

“…Results Pre-pandemic, SO remained stable or declined in children under 12 until 2010: OR5: 0.8-1, p<0.001) but rose significantly afterward (OR5: 1.1-1.2, p<0.001). Children between 12-16 years of age showed a continuous increase, especially boys (boys12-16: OR5: 1.3, girls12-16: OR5: 1.1, p<0.001). …”

Supplementary file 1_Effects of aging and valence on emotional response inhibition: conclusions from a novel stop-signal task.xlsx by Jill D. Waring (6652103)

“…Aging is associated with decreasing cognitive control and inhibition alongside improvements in emotional control and regulation. …”

Image1_Neutrophil-activating protein in Bacillus spores inhibits casein allergy via TLR2 signaling.jpeg by Zhuwei Liang (8762337)

“…</p>Results<p>NAP recombinant spore treatment significantly reduced allergic symptoms and intestinal inflammation. …”

Data Sheet 6_Beyond salt tolerance: SOS1-13’s pivotal role in regulating the immune response to Fusarium oxysporum in Solanum phureja.docx by Liqin Liang (652560)

“…Conversely, silencing the ortholog gene NbSOS1-13 in Nicotiana benthamiana showed more accumulation of ROS, serious cell necrosis, reduced activities of SOD and CAT, significantly increased MDA level, obvious leaf wilting, decreased tolerance to infection, and reduced leaf stomatal closure rate and accelerated stomatal area. …”

Image2_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG by Wen Zhou (49050)

“…</p>Results<p>The results showed that C16 significantly improved the clinical score and cortical somatosensory/motor evoked potential. …”

Image6_Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model.JPEG by Wen Zhou (49050)

“…</p>Results<p>The results showed that C16 significantly improved the clinical score and cortical somatosensory/motor evoked potential. …”

Data Sheet 1_Brain-derived uroguanylin as a regulator of postprandial brown adipose tissue activation: a potential therapeutic approach for metabolic disorders.docx by Nikola Habek (21178259)

“…In this study, we aim to determine the expression of uroguanylin (UGN) in the mouse and human brain, its regulatory mechanisms, and its significance to patients with obesity and type 2 diabetes (T2D).…”

Table 6_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.xlsx by Miguel Ângelo-Dias (20936444)

“…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …”

Supplementary Material for: Role of Raf Kinase Inhibitor Protein in Modulating Echinococcal Cyst Fluid-induced Degranulation in Bone Marrow-Derived Mast Cells by figshare admin karger (2628495)

“…Following sensitization, BMMCs from the KO group demonstrated significantly higher degranulation rates compared to the WT group (p < 0.05). …”

Data Sheet 1_Phyllosphere microbiome responses to nano-berberine and chemical fungicides in powdery mildew infected strawberry.pdf by Meng Yang (162251)

“…The results showed that nano-fungicide application significantly reduced the disease index of powdery mildew and markedly decreased its incidence in field-grown strawberries, ultimately lowering leaf disease incidence to 5.06% with a control efficacy of 96.81%. …”

Effect of HPC silencing on phase-locking of PFC neurons to local theta. by Susanne S. Babl (21169261)

“…Percentage of neurons significantly phase-locked to PFC theta oscillations (4–12 Hz) in the sample <b>(A)</b> and choice phase <b>(B)</b> during light-off and light-on trials. …”

Table 7_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx by Linling Du (22827035)

“…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…”

pH sensitive lipid polymeric hybrid nanoparticle (LPHNP) of paclitaxel and curcumin for targeted delivery in breast cancer by Hrishikesh Sarma (14827761)

“…MTT-assay studies revealed enhanced cytotoxicity of CUR and PTX as LPHNPs showing IC₅₀ value of free CUR & PTX 480.06 µg/mL decreasing to 282.97 µg/mL for CS-CUR-PTX-LPHNPs. <i>In vivo</i> pharmacokinetic evaluations in rats confirmed significantly improved bioavailability, with a 3.8-fold increase in AUC for CUR and a 6.6-fold increase for PTX. …”

Data Sheet 2_Identification of novel gut microbiota-related biomarkers in cerebral hemorrhagic stroke.zip by Fengli Ye (22123540)

“…Machine learning identified four hub genes—LEF1, ITGAX, BLVRB, and ATF4. All were significantly upregulated in ICH tissues and plasma, correlating with immune cell infiltration. …”

Image 2_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.tif by Linling Du (22827035)

“…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…”

Supplementary file 2_Effects of Lactiplantibacillus plantarum DSM 33464 in children with elevated blood lead levels: a randomized, double-blind, placebo-controlled study.docx by Wenjing Ji (720509)

“…Introduction<p>Approximately one-third of the world’s children have elevated blood lead levels (BLLs), which may lead to often-irreversible decreased intelligence, behavioral difficulties, and learning problems. …”

Data Sheet 1_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.pdf by Sadia Hamera (22524803)

“…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …”

Table 2_Slavs in the closet: computational genomic analysis reveals cryptic slavic signatures in the Avar Khaganate and their contribution to medieval Croatian population formation... by Todor Chobanov (22288636)

“…This approach revealed substantial Baltic genetic components in early Slavic populations (57% in Slovakia/Slovenia) decreasing to 39%–51% in medieval Croatian samples. …”

Data Sheet 1_A novel bioactive peptide-peptoid hybrid of alpha-calcitonin gene-related peptide protects against pressure-overload induced heart failure.docx by Ambrish Kumar (558337)

“…NMEG-CGRP administration significantly attenuated these TAC-induced adverse cardiac effects in the HF mice.…”

Data Sheet 4_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.pdf by Sadia Hamera (22524803)

“…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …”