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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant changes » significant challenge (Expand Search)
significant cause » significant change (Expand Search), significant gap (Expand Search), significant increase (Expand Search)
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20501
Supplementary file 2_Integrating single-cell RNA-seq, bulk RNA-seq and network pharmacology reveals protective effect of salidroside in peritoneal dialysis-associated peritoneal fi...
Published 2025“…In a murine model of peritoneal fibrosis induced by intraperitoneal injection of 4.25% PD fluid, SAL treatment significantly mitigated peritoneal fibrosis, as evidenced by reduced collagen deposition, decreased protein expression of α-smooth muscle actin and Collagen I, and a thinner peritoneum. …”
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20502
Tilmicosin inhibits the infections of currently prevalent porcine reproductive and respiratory syndrome viruses via the downregulation of CD163 expression
Published 2025“…Remarkably, the transcriptomic analysis provided the first clue that PRRSV key receptor CD163 was significantly downregulated by tilmicosin, which was further confirmed by qPCR and WB detections. …”
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20503
Image 1_Yacon root is a functional food beneficial for human health: a meta-analysis of clinical trials.pdf
Published 2025“…The pooled results showed that YR significantly reduced BMI [SMD = −0.81, 95%CI (−1.54, −0.08)], decreased stool pH [SMD = −1.12, 95%CI (−1.61, −0.62)], softened stools [SMD = 0.94, 95%CI (0.08, 1.80)], facilitated defecation [SMD = 4.03, 95% CI (0.54, 7.52)], improved fiber consumption patterns [SMD = 0.58, 95%CI (0.18, −0.99)]. …”
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20504
Data Sheet 1_Chito-oligosaccharide composites enhanced the adaptability of cotton seedlings to salinized soil by modulating photosynthetic efficiency and metabolite.doc
Published 2025“…The results showed that salt stress reduced the contents of K<sup>+</sup> and Ca<sup>2+</sup> and enhanced the content of Na<sup>+</sup> in cotton leaves compared to the control, which inhibited leaf photosynthesis and seedling growth. COS-PA application decreased leaf Na<sup>+</sup> content significantly in salt-stressed cotton seedlings by 69.70%, and increased the leaf Ca<sup>2+</sup> content, fresh weight of each plant part, transpiration rate, leaf chlorophyll concentration (Chl a), actual quantum yield, as well as stomatal conductance by 7.22%, 46.33%-96.36%, 96.65%, 44.53%, 27.15%, and 168.24%, respectively, compared with the no COS-PA application treatment. …”
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20505
Identification of multicohort-based predictive signature for NMIBC recurrence reveals SDCBP as a novel oncogene in bladder cancer
Published 2025“…Experimental procedures demonstrated that silencing SDCBP attenuated cell growth, glucose metabolism and extracellular acidification rate, accompanied by decreased expression of p-AKT, p-ERK1/2, LDHA and Vimentin.…”
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20506
Correlation coefficient matrix.
Published 2025“…Following model updates with measured data, the accumulated prediction error rapidly decreases. The proposed prediction method for shape errors during pushing exhibits high accuracy and versatility in similar projects, significantly reducing time spent on manual error handling and minimizing computational inaccuracies.…”
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20507
Actual measurement of shape errors.
Published 2025“…Following model updates with measured data, the accumulated prediction error rapidly decreases. The proposed prediction method for shape errors during pushing exhibits high accuracy and versatility in similar projects, significantly reducing time spent on manual error handling and minimizing computational inaccuracies.…”
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20508
Long-Term Outcomes of Pediatric Pars Planitis: Retrospective Cohort from a Single Tertiary Center in Turkey
Published 2025“…At the final examination, the mean BCVA of the right and left eyes improved significantly (0.08 ± 0.23 and 0.06 ± 0.17, <i>p</i> = 0.006 and <i>p</i> < 0.001, respectively). …”
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20509
Apelin deficiency exacerbates cardiac injury following infarction by accelerating cardiomyocyte ferroptosis
Published 2024“…Ferroptosis-related proteins were significantly increased post-MI in Apelin<sup>−/−</sup> mice whereas p-AMPK was greatly decreased. …”
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20510
Table 1_Ionizing radiation improves skin bacterial dysbiosis in cutaneous T-cell lymphoma.docx
Published 2024“…Both α and β-diversity differed significantly post versus pre-IR for TSEBT, but not for local IR. …”
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20511
Data Sheet 1_Peripheral circular RNAs hsa_circ_0075436 and hsa_circ_0005729 as diagnostic and prognostic biomarkers in acute ischemic stroke: expression profiles and mechanistic in...
Published 2025“…</p>Results<p>Two circRNAs, hsa_circ_0075436 and hsa_circ_0005729, significantly decreased in PBMCs of AIS patients. The expressive levels negatively correlated with NIH Stroke Scale (NIHSS) scores at admission and discharge. …”
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20512
Image 2_Age-dependent effects of H2S on post-traumatic stress disorder in adolescent and adult mice.jpeg
Published 2025“…Administration of exogenous H<sub>2</sub>S significantly improved anxiety and depression-like behavior, mitigated synaptic plasticity deficits, and activated the CREB/BDNF signaling pathway in the hippocampus of adolescent PTSD mice. …”
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20513
Table 2_Ionizing radiation improves skin bacterial dysbiosis in cutaneous T-cell lymphoma.xlsx
Published 2024“…Both α and β-diversity differed significantly post versus pre-IR for TSEBT, but not for local IR. …”
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20514
Table 1_MFN2-a multifaceted guardian against Parkinson’s pathophysiology: mitochondria, ferroptosis, inflammation and oxidative stress.docx
Published 2025“…</p>Results<p>In PD models, the expressions of DHODH, MFN1, MFN2, GPX4, and FSP1 were significantly down-regulated, and their motor coordination, self-cognitive behavior, and exploration ability were decreased. …”
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20515
Supplementary file 1_Synergistic effects of potassium and gibberellin on the yield and quality of yellow pitahaya (Hylocereus megalanthus) fruits in the Peruvian Amazon.docx
Published 2025“…The combination of 100 kg K<sub>2</sub>O ha⁻¹ and 50 mg L⁻¹ GA<sub>3</sub> significantly improved fruit performance, with fruit weight (369.5 g), yield (12 t ha⁻¹), volume (322 cm³), and soluble solids (22.8°Brix), while acidity decreased (pH 4.87 vs. 4.55 in the control). …”
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20516
Image 1_Neuroimaging and molecular mechanism of action of Cang-ai volatile oil in the treatment of vascular cognitive impairment.tif
Published 2025“…</p>Conclusion<p>This study demonstrates that CAVO therapy reduces inflammatory responses in brain regions of VCI rats, decreases apoptosis and necrosis, protects neurons in affected areas, and simultaneously enhances functional connectivity strength between brain regions in VCI rats, thereby exerting a cognitive-improving effect on VCI.…”
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20517
DataSheet1_Predicting the solubility of CO2 and N2 in ionic liquids based on COSMO-RS and machine learning.docx
Published 2024“…The results show that the COSMO-RS with correction can significantly improve the prediction of CO<sub>2</sub> solubility, and the corresponding average absolute relative deviation (AARD) is decreased from 43.4% to 11.9%. …”
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20518
Table 2_CqHKT1 and CqSOS1 mediate genotype-dependent Na+ exclusion under high salinity conditions in quinoa.xlsx
Published 2025“…By contrast, K<sup>+</sup> accumulation was slightly reduced in the aerial parts but significantly decreased in the roots of all the genotypes. …”
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20519
Image 1_Resveratrol and β-hydroxy-β-methylbutyric acid supplementation promotes ileal development and digestive function by altering microbial community abundance and metabolites i...
Published 2024“…</p>Results<p>Results indicated that dietary RES and (or) HMB supplementation significantly improved the phenotype (mucosal thickness and villus width), SCFAs concentrations, and digestive enzymes (lipase, cellulase, and α-amylase) (p < 0.05). …”
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20520
Trends and Disparities in Rates of Hypoglycemia Among Hospitalized Patients with Type II Diabetes
Published 2025“…</p><p dir="ltr">Results: Among 512,261 patients hospitalized with diabetes, 6.8% (34,918) had an episode of hypoglycemia (< 70 mg/dl). This rate decreased by 17% from 2016-2022 (7.4% to 6.3%) while the rate of discharge diagnosis among those with hypoglycemia increased. …”