PRISMA flowchart of the study selection process. حسب Yohannis Derbew Molla (16471771)

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Fer-1 alleviated liver lesions caused by <i>C. sinensis.</i> حسب Haoyang Zhang (1706815)

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Inhibition of ferroptosis alleviated liver fibrosis caused by <i>C. sinensis.</i> حسب Haoyang Zhang (1706815)

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ALKG1202R –ABT199 interactions. حسب Richard Junior Zapata Dongo (17912565)

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ALKC1156Y –ABT199 interactions. حسب Richard Junior Zapata Dongo (17912565)

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S1 Data - حسب Richard Junior Zapata Dongo (17912565)

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Combination therapy exhibited apoptosis in Ba/F3 EML4-ALKmutant cell models. حسب Richard Junior Zapata Dongo (17912565)

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Ba/F3 EML4-ALK^mutants exhibit variable dose-response to ABT-199 treatment. حسب Richard Junior Zapata Dongo (17912565)

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Molecular docking showed that ABT-199 can fit into active site of ALK^Mutant. حسب Richard Junior Zapata Dongo (17912565)

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The binding energy values of ATP, ALK inhibitors and ABT-199 to ALK were obtained from AlphaFold and modeled protein structures. حسب Richard Junior Zapata Dongo (17912565)

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Amino acids interactions and binding energy describe that ABT-199 binds to ALK^Mutant. حسب Richard Junior Zapata Dongo (17912565)

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Western blot analysis of drug combinations. حسب Richard Junior Zapata Dongo (17912565)

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ALKL1196M –ABT199 interactions. حسب Richard Junior Zapata Dongo (17912565)

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ALK^wt–ABT199 interactions. حسب Richard Junior Zapata Dongo (17912565)

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BCL2 protein keeps their expression in different conditions treatment nevertheless each EML4-ALK cell modells exhibit variable expression. حسب Richard Junior Zapata Dongo (17912565)

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ALK inhibitors (Positive control) and ABT199 (Proposed binding) in complex with the ALK active side. حسب Richard Junior Zapata Dongo (17912565)

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BCL2 antiapoptotic protein exhibits heterogeneous expression in Ba/F3 EML4-ALK^mutants. حسب Richard Junior Zapata Dongo (17912565)

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Loewe synergy-antagonism score analysis shows additive and synergistic effects after ALKi and ABT-199 combination treatment. حسب Richard Junior Zapata Dongo (17912565)

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Negative (Prednisone) and basal (ATP) control compounds binding to ALK protein. حسب Richard Junior Zapata Dongo (17912565)

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Scatter plots of the relationships between age and the proportions of cells which statistically significantly correlated with age. حسب Arttu Autio-Kimura (20454681)

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