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significant cause » significant change (Expand Search), significant gap (Expand Search), significant increase (Expand Search)
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18981
Table 1_Integrated gut microbiota and metabolomic profiling reveals key associations between amino acid levels and gut microbial composition in patients with obesity.docx
Published 2025“…Metabolomic analysis revealed that in patients with obesity, the abundance of carnosine (log2FC = 1.16, FDR = 0.0016, VIP = 0.707), creatinine (log2FC = 0.21, FDR = 0.0009, VIP = 2.02), and cystine (log2FC = 0.55, FDR = 0.009, VIP = 1.47) was significantly increased compared with that in the controls; in contrast, that of ornithine (log2FC = −0.59, FDR = 0.0009, VIP = 1.19), citrulline (log2FC = −0.59, FDR = 0.0003, VIP = 0.707), glycine (log2FC = −0.54, FDR = 0.0003, VIP = 1.41), and serine (log2FC = −0.38, FDR = 0.0019, VIP = 1.62) was significantly decreased. …”
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18982
NHR-49/80 mediated FEDUS via the peroxisomal activation.
Published 2024“…Lower population density significantly decreased palmitic acid-induced AWC maturation. …”
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18983
<b>Selective Reduction of Ca</b><sup><strong>2+</strong></sup><b>-Independent Phospholipase A</b><sub><strong>2</strong></sub><b>b</b><b> (iPLA</b><sub><strong>2</strong></sub><b>b...
Published 2024“…</p><p dir="ltr">· Reduction of myeloid-iPLA<sub>2</sub>b decreases T1D incidence.</p><p dir="ltr"><br><b>d. …”
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18984
Table 1_Immunoglobulin G N-Glycome as a biomarker of mortality risk in Escherichia coli induced sepsis.docx
Published 2025“…</p>Results<p>We identified that the fucosylation level was significantly decreased in patients. Importantly, bisecting GlcNAc, sialylation, and galactosylation have different levels between sepsis and control groups. …”
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18985
Data Sheet 3_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf
Published 2025“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”
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18986
Data Sheet 1_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf
Published 2025“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”
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18987
Data Sheet 4_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf
Published 2025“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”
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18988
Data Sheet 5_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf
Published 2025“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”
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18989
Data Sheet 2_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.docx
Published 2025“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”
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18990
Table1_The role of SIRT1-FXR signaling pathway in valproic acid induced liver injury: a quantitative targeted metabolomic evaluation in epileptic children.DOCX
Published 2024“…Only three bile acid metabolites, taurodeoxycholic acid, taurochenodeoxycholic acid, and deoxycholic acid, were significantly different between the ANLF1 and ANLF2 groups, increasing at first and then decreasing with the aggravation of liver injury. …”
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18991
Scorpion venom cytolytic peptide Smp43 induces caspase-dependent apoptosis in ovarian carcinoma cell line OVCAR-3
Published 2025“…Additionally, Smp43 significantly increased DNA fragmentation in OVCAR-3 cells and decreased antioxidant parameters. …”
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18992
Data Sheet 1_Straw return was more beneficial to improving saline soil quality and crop productivity than biochar in the short term.docx
Published 2025“…In relation to CK and CB, CS significantly improved SQI by 52% and 35%, respectively. …”
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18993
Image 2_Distribution and metabolism of iPSC-MSCs in the joint cavity of an osteoarthritis rat model.jpeg
Published 2025“…</p>Result<p>Histopathological results demonstrated that iPSC‐MSCs significantly reversed joint tissue damage of arthritic rats. …”
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18994
Image 1_Distribution and metabolism of iPSC-MSCs in the joint cavity of an osteoarthritis rat model.jpeg
Published 2025“…</p>Result<p>Histopathological results demonstrated that iPSC‐MSCs significantly reversed joint tissue damage of arthritic rats. …”
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18995
Image 3_Distribution and metabolism of iPSC-MSCs in the joint cavity of an osteoarthritis rat model.tif
Published 2025“…</p>Result<p>Histopathological results demonstrated that iPSC‐MSCs significantly reversed joint tissue damage of arthritic rats. …”
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18996
Image 8_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.pdf
Published 2025“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. The burden of ischemic stroke attributable to ambient and household PM2.5 exhibited considerable heterogeneity across 204 countries. …”
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18997
Table 5_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.xlsx
Published 2025“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. The burden of ischemic stroke attributable to ambient and household PM2.5 exhibited considerable heterogeneity across 204 countries. …”
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18998
Table 10_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.xlsx
Published 2025“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. The burden of ischemic stroke attributable to ambient and household PM2.5 exhibited considerable heterogeneity across 204 countries. …”
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18999
Image 3_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.pdf
Published 2025“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. The burden of ischemic stroke attributable to ambient and household PM2.5 exhibited considerable heterogeneity across 204 countries. …”
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19000
Image 5_Spatiotemporal trends of ischemic stroke burden attributable to PM2.5 from 1990 to 2021.pdf
Published 2025“…The age-standardized rates (ASRs) of ischemic stroke linked to ambient PM2.5 slightly declined, while those associated with household PM2.5 significantly decreased over the past 32 years. The burden of ischemic stroke attributable to ambient and household PM2.5 exhibited considerable heterogeneity across 204 countries. …”