Search alternatives:
significant decrease » significantly increased (Expand Search)
significance b » significance _ (Expand Search), significance set (Expand Search), significant _ (Expand Search)
b decrease » _ decrease (Expand Search), a decrease (Expand Search), b1 decreased (Expand Search)
significant decrease » significantly increased (Expand Search)
significance b » significance _ (Expand Search), significance set (Expand Search), significant _ (Expand Search)
b decrease » _ decrease (Expand Search), a decrease (Expand Search), b1 decreased (Expand Search)
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IQGAP1 is a protein that plays a critical role in regulating the level of apoptosis in endothelial cells.
Published 2025“…(B) The EdU assay reveals that Si-IQGAP1 can slightly increase EC proliferation. …”
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1527
Inhibiting IQGAP1 expression restricts atherosclerotic plaque development.
Published 2025“…(D) The TUNEL assay demonstrates that the number of apoptotic cells are significantly decreased in the AAV-Si-IQGAP1 group. (E,F) Western blot and densitometric analyses of each protein relative to β‐actin reveal decreased expression of IQGAP1, and pro-apoptotic proteins (cleaved caspase-3 and BAX), while YAP and the anti-apoptotic protein BCL-2 are increased in the aortic wall of the AAV-Si-IQGAP1 groups. …”
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Abnormal expression of IQGAP1, cleaved caspase-3, BCL‐2, and BAX in the aortic wall of HFD mice and AS plaque.
Published 2025“…(D) The TUNEL assay demonstrates significantly increased numbers of apoptotic cells in the aortas of HFD mice. …”
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Electroretinogram (ERG) recordings from 6-, 9-, and 12-month mice show deficits in 5xFAD photoreceptors.
Published 2025“…(C) Quantification of A- and B-wave amplitudes at the highest intensity stimulus (3.0000 cd * s/m<sup>2</sup>) shows the significant increase and decrease in retinal function in the 6- and 9-month 5xFAD mice, respectively, analyzed by two-way ANOVA with Tukey’s multiple comparisons. …”
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Mechanism of hydrocephalus formation involving inflammation after IVH.
Published 2025“…When NF-κB is inhibited after ventricular hemorrhage, a significant reduction in the size of the bilateral lateral ventricles is observed, along with a slowed CSF secretion rate and decreased expression of NF-κB and AQP1 proteins in CPEs. …”
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