Table 1_Conditional knockdown of hepatic PCSK9 ameliorates high-fat diet-induced liver inflammation in mice.docx حسب Xue-Ying Zhang (144147)

"…Moreover, the findings were verified in vitro using HepG2 cells.</p>Results and Discussion<p>Conditional knockdown of hepatic PCSK9 remarkably decreased plasma levels of total cholesterol and alleviated hyperlipidemia-induced liver injury. …"

DataSheet1_Enhancing resistant starch fraction in modified elephant foot yam starch: optimizing preparation conditions and exploring tribological properties.pdf حسب Sreejani Barua (13810723)

"…However, this retention decreased significantly to 1.08% after 10 min of cooking. …"

<b>Metabolic Improvements with Tirzepatide in Lipodystrophy: A Novel Option?</b> حسب Rasimcan Meral (5022425)

"…After a median 8.7 months of follow-up, BMI (medianΔ -1.7; range -5.9 to 0.9 kg/m2; p=0.008), HbA1c (medianΔ -1.1%; range -6.3 to -0.1%; p<0.001), triglycerides [medianΔ -65 mg/dL (-0.73 mmol/L); range -3820 to 43 mg/dL (-43.2 to 0.49 mmol/L); p=0.003] and total daily insulin requirements (medianΔ -109; range -315 to 0 units/day; p=0.002) were significantly reduced. …"

Effect of HPC silencing on phase-locking of PFC neurons to local theta. حسب Susanne S. Babl (21169261)

"…<p><b>(AB)</b>. Percentage of neurons significantly phase-locked to PFC theta oscillations (4–12 Hz) in the sample <b>(A)</b> and choice phase <b>(B)</b> during light-off and light-on trials. …"

Data Sheet 1_A novel short-course, low-intensity blood-flow-restricted exercise (BFRE) regimen to study satellite cell function in critical illness survivors with sustained muscle... حسب Sunita Mathur (759075)

"…Decreased satellite cell content is reported in the atrophic muscle of critical illness survivors, suggesting that the sustained muscle wasting results from satellite cell dysfunction and impaired muscle regeneration. …"

Graphic abstract of the study. حسب Donglin Yang (490406)

"…The results showed that the expression of circRNAs in serum exosomes of DN patients was significantly down-regulated, and hsa_circ_0006382 and hsa_circ_0019539 targeted the expression of FGF9 by binding to miR-34a-5p, miR-766-3p, miR-147a and miR-27a-3p. …"

Raw data. حسب Donglin Yang (490406)

"…The results showed that the expression of circRNAs in serum exosomes of DN patients was significantly down-regulated, and hsa_circ_0006382 and hsa_circ_0019539 targeted the expression of FGF9 by binding to miR-34a-5p, miR-766-3p, miR-147a and miR-27a-3p. …"

Unraveling the immunosuppressive role of Elastase B produced by cystic fibrosis isolates of <i>Pseudomonas aeruginosa</i> in an organotypic 3D lung epithelial cell model حسب Merel Wauters (21333023)

"…Therefore, we determined the contribution of LasB to the observed reduction in cytokine levels by utilizing <i>P. aeruginosa lasB</i> knockout mutants. Compared to the <i>lasB</i> mutant, the wild-type strain significantly decreased inflammation by degrading MCP-1, IL-1β, GM-CSF, and IL-8. …"

Matched data. حسب Feng Zhang (6548)

"…Decision curve analysis indicated that the net benefit of predicting false-negative IGRA results using this nomogram model was greater than 0 when the threshold probability ranged from 0.15 to 0.95.</p><p>Conclusion</p><p>Decreased RBC/ALB and elevated NLR may be pivotal factors contributing to false-negative IGRA results in PTB patients. …"

Nomogram model. حسب Feng Zhang (6548)

"…Decision curve analysis indicated that the net benefit of predicting false-negative IGRA results using this nomogram model was greater than 0 when the threshold probability ranged from 0.15 to 0.95.</p><p>Conclusion</p><p>Decreased RBC/ALB and elevated NLR may be pivotal factors contributing to false-negative IGRA results in PTB patients. …"

Flowchart of Study Design and Analysis. حسب Feng Zhang (6548)

"…Decision curve analysis indicated that the net benefit of predicting false-negative IGRA results using this nomogram model was greater than 0 when the threshold probability ranged from 0.15 to 0.95.</p><p>Conclusion</p><p>Decreased RBC/ALB and elevated NLR may be pivotal factors contributing to false-negative IGRA results in PTB patients. …"

Multivariate Binary Logistic Regression Analysis. حسب Feng Zhang (6548)

"…Decision curve analysis indicated that the net benefit of predicting false-negative IGRA results using this nomogram model was greater than 0 when the threshold probability ranged from 0.15 to 0.95.</p><p>Conclusion</p><p>Decreased RBC/ALB and elevated NLR may be pivotal factors contributing to false-negative IGRA results in PTB patients. …"

ROC curve. حسب Feng Zhang (6548)

"…Decision curve analysis indicated that the net benefit of predicting false-negative IGRA results using this nomogram model was greater than 0 when the threshold probability ranged from 0.15 to 0.95.</p><p>Conclusion</p><p>Decreased RBC/ALB and elevated NLR may be pivotal factors contributing to false-negative IGRA results in PTB patients. …"

Unmatched data. حسب Feng Zhang (6548)

"…Decision curve analysis indicated that the net benefit of predicting false-negative IGRA results using this nomogram model was greater than 0 when the threshold probability ranged from 0.15 to 0.95.</p><p>Conclusion</p><p>Decreased RBC/ALB and elevated NLR may be pivotal factors contributing to false-negative IGRA results in PTB patients. …"

Calibration curve. حسب Feng Zhang (6548)

"…Decision curve analysis indicated that the net benefit of predicting false-negative IGRA results using this nomogram model was greater than 0 when the threshold probability ranged from 0.15 to 0.95.</p><p>Conclusion</p><p>Decreased RBC/ALB and elevated NLR may be pivotal factors contributing to false-negative IGRA results in PTB patients. …"

Decision curves. حسب Feng Zhang (6548)

"…Decision curve analysis indicated that the net benefit of predicting false-negative IGRA results using this nomogram model was greater than 0 when the threshold probability ranged from 0.15 to 0.95.</p><p>Conclusion</p><p>Decreased RBC/ALB and elevated NLR may be pivotal factors contributing to false-negative IGRA results in PTB patients. …"

Data Sheet 1_Investigating the spatial limits of somatotopic and depth-dependent sensory discrimination stimuli in rats via intracortical microstimulation.docx حسب Thomas J. Smith (224833)

"…We demonstrate that the rats were able to reliably discriminate between the most superficial (450–750 μm) and deepest (1650–1950 μm) single-shank patterns with 90% accuracy, whereas discrimination between the most superficial and next adjacent pattern (650–950 μm) significantly dropped to 53% (p < 0.05). Similarly, in the four-shank group, discrimination accuracy was 88% for the furthest pattern pairs (375 μm difference) but significantly fell to 62% (p < 0.05) for the closest pairs (125 μm difference). …"

Supplementary Material for: Protein inhibitor of activated STAT 2 (PIAS2) protects against podocyte injury in diabetic nephropathy via inhibiting JAK2/STAT3 pathway حسب figshare admin karger (2628495)

"…Overexpression of PIAS2 significantly reversed high glucose-induced human podocytes injury, evidenced by increased cell viability, reduced cell apoptosis, decreased expression of pro-apoptotic proteins Bax and cleaved-Caspase3, increased expression of the anti-apoptotic protein Bcl-2, and reduced secretion of pro-inflammatory cytokines IL-1β, IL-6, and TNF-α. …"

<i>Edwardsiella piscicida</i> employs C3 derivative to mediate internalization and infection via the teleost-specific receptor حسب Mo-Fei Li (21624535)

"…When PoCD18 was knocked down or blocked, bacterial infection and tissue lesions were significantly decreased. Mechanistically, the intracellular domain of PoCD18 subsequently interacted with PoCytohesin and triggered the phosphorylation of the phosphatidylinositol 3-kinase (PI3K)/serine-threonine protein kinase (Akt) signalling pathway. …"

Supplementary file 2_Integrating single-cell RNA-seq, bulk RNA-seq and network pharmacology reveals protective effect of salidroside in peritoneal dialysis-associated peritoneal fi... حسب Shuting Li (6552)

"…In a murine model of peritoneal fibrosis induced by intraperitoneal injection of 4.25% PD fluid, SAL treatment significantly mitigated peritoneal fibrosis, as evidenced by reduced collagen deposition, decreased protein expression of α-smooth muscle actin and Collagen I, and a thinner peritoneum. …"