Data Sheet 1_IL-10 to lymphocyte ratio (ILR) and lactate in the prognosis prediction and risk stratification of sepsis: a pilot study.docx حسب Yuan Yan (1501603)

"…Based on stratification by ILR (cutoff value 97.4) and Lac (cutoff value 4.1 mmol/L), the four risk stratification levels (Levels I–IV) exhibited progressively decreasing 28-day mortality rates: Level I (78.95%), Level II (50.00%), Level III (15.38%), and Level IV (7.69%). …"

Data Sheet 1_Post-COVID syndrome patients show reduced anti-Spike antibodies compared to COVID-recovered controls, but enhanced IgG4/IgG1 switch after the third vaccine dose.pdf حسب Nineth Rossi (22355524)

"…Introduction<p>Long COVID and post-COVID syndromes represent a significant global health crisis and a substantial societal challenge. …"

Data Sheet 1_Global, regional, and national burdens of endometriosis from 1990 to 2021: a trend analysis.docx حسب Hailan Yan (18174379)

"…Background<p>Endometriosis is a common, chronic, estrogen-dependent gynecological disorder that significantly affects patients’ quality of life. However, the disease burden and its trends may be undergoing significant changes, and comprehensive data on this issue are currently lacking. …"

Table 1_Global, regional, and national disease burden and economic costs of cervical cancer (1991–2021): a multidimensional data synthesis analysis.docx حسب Yidi Ma (9507153)

"…Objectives<p>Cervical cancer remains a significant global health concern, particularly in less developed regions. …"

Data Sheet 1_Comparison of intravascular imaging, physiological assessment and angiography for coronary revascularization in acute coronary syndrome: a systematic review and networ... حسب Xuan-Yan Liu (19362096)

"…Patients who received quantitative flow ratio (QFR)-guided PCI experienced lower all-cause mortality (RR: 0.25; 95%CI: 0.07–0.92) vs. those receiving angiography. Similarly, the RR decreased to 0.64 after using FFR-guided PCI vs. angiographic procedures (95% CI: 0.44–0.91). …"

<b><i>N</i></b>^{<strong>6</strong>}<b>-Methyladenosine demethylase FTO controls</b><b>macrophage homeostasis in diabetic vasculopathy</b> حسب Siguo Feng (19924429)

"…</p><p><br></p><p><br></p><p><br></p><p><br></p><p><br></p><p><br></p><p><br></p><p><br></p><p><br></p><p dir="ltr"><b>ARTICLE HIGHLIGHTS</b></p><p dir="ltr">Ÿ FTO is a key regulator for decreased m⁶A modification in diabetes-induced macrophage polarization.…"

Table 1_Association of the ROX index with mortality in sepsis patients: a retrospective study.docx حسب Jiali Wu (701228)

"…Restricted cubic spline analysis revealed a nonlinear “L”-shaped association, with the 28-day mortality risk decreasing until reaching a plateau at a ROX index of approximately 10.50. …"

Data Sheet 1_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.zip حسب Li Cui (37567)

"…ART effectively reduced BMI, improved glycemic control, and decreased inflammatory markers through mechanisms involving AMPK and mTOR pathways. …"

Identification of novel pathogenic mutations in <i>ATP6V0A4</i> associated with distal renal tubular acidosis and analysis of wild-type expression in glomerular disease حسب Yaru Jiang (17458815)

"…If untreated, it can result in a significant electrolyte imbalance and progressive chronic kidney disease (CKD). …"

Data Sheet 1_CD44 knockdown alters miRNA expression and their target genes in colon cancer.pdf حسب Diana Maltseva (11678641)

"…Collectively, these effects decreased the metastatic potential of the CRC xenograft tumors under investigation. …"

Data Sheet 1_An alternative structured weight management protocol to rapid weight loss in mixed martial arts: a prospective interventional study of pre-competition weight managemen... حسب Clóvis Albuquerque Maurício (22389121)

"…Starting 7 days before the weigh-in, athletes consumed 7 liters of fluids per day, with intake gradually decreasing. On the day before the weigh-in, they consumed only 0.5 liters. …"

Table 1_Outcomes of mini-monovision with monofocal, enhanced monofocal and extended depth-of-focus intraocular lenses.docx حسب Issac Levy (20762594)

"…</p>Conclusion<p>While enhanced monofocal and EDOF IOLs may provide slightly better binocular intermediate visual outcomes and higher spectacle independence compared to monofocal lenses with regards to mini-monovision and intermediate vision performance, the differences are not statistically significant. All three IOL types exhibit high patient satisfaction rates when choosing a mini-monovision approach with decreased dependence on spectacles.…"

CRISPR/Cas9-mediated editing of barley lipoxygenase genes promotes grain fatty acid accumulation and storability حسب Zhanghui Zeng (3571331)

"…Compared to the wild-type, all mutants displayed normal plant height, tiller number, and grain size, although the <i>loxC1</i> and <i>loxAloxC1</i> mutants exhibited significantly lower thousand grain weights. Notably, the total LOX activity in mature grains decreased by 36–42% in <i>loxC1</i> mutants and by 94% in <i>loxAloxC1</i> mutants, with no significant change observed in <i>loxB</i> mutants. …"

Baseline characteristics of the study population. حسب Vatsala Rajendram (20691806)

"…Widespread use of the measles vaccine has decreased measles antibody potency in the United States plasma supply. …"

Supplementary file 2_Exploring dupilumab for asthma: from mechanistic insights to clinical outcomes, safety, and cost-effectiveness.docx حسب Omar Z. Ameer (8900039)

"…Clinical trials have demonstrated significant reductions in asthma exacerbation rates, improvements in forced expiratory volume in one second (FEV₁), and decreased oral corticosteroid (OCS) dependence in adults and children with moderate-to-severe asthma. …"

Supplementary file 1_Bioinformatics analysis combined with experimental validation reveals the novel mechanisms of multi-targets of dapagliflozin attenuating diabetic liver injury.... حسب Pengyu Wang (6680312)

"…</p>Results<p>Dapagliflozin alleviated diabetic liver injury by decreasing lipid deposition, oxidative stress levels, the inflammatary and apoptosis-related proteins and mRNA levels, while it also reducing blood glucose. …"

Image 1_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.png حسب Li Cui (37567)

"…ART effectively reduced BMI, improved glycemic control, and decreased inflammatory markers through mechanisms involving AMPK and mTOR pathways. …"

Data Sheet 1_Sex differences in burnout and work-family conflict among Chinese emergency nurses: a cross-sectional study.docx حسب Dongmei Diao (447916)

"…</p>Conclusion<p>Reducing depersonalization among emergency department male nurses and emotional exhaustion and depersonalization for female emergency department nurses, are crucial for decreasing work–family role behavior conflicts. Future studies should explore differences in burnout level among male and female nurses for a long time.…"

Data Sheet 2_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.pdf حسب Christina Stevens (9737867)

"…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. However, only age, hindlimb joint pain, and hindlimb muscle atrophy had statistically significant effects on physical activity.…"

Table 1_Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia.docx حسب Yu Zhou (89766)

"…Extending these findings in vivo, MK-801–treated mice exhibited behavioral and neuronal deficits, reduced ATP5A fluorescence intensity, and decreased ATP concentrations; expression of all four hub genes was significantly altered, with three (MALAT1, PPIL3, and ITM2A) concordant with transcriptomic results. …"