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significant decrease » significantly increased (Expand Search)
significant all » significant anti (Expand Search), significant gap (Expand Search), significant _ (Expand Search)
all decrease » small decrease (Expand Search), a decrease (Expand Search), fold decrease (Expand Search)
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20501
Data Sheet 3_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway....
Published 2025“…Antioxidant enzyme activities (SOD, CAT) increased, while oxidative stress markers (MDA) and inflammatory cytokines (IL-1β, IL-6, TNF-α) decreased (p < 0.01). …”
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20502
Table 7_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx
Published 2025“…Antioxidant enzyme activities (SOD, CAT) increased, while oxidative stress markers (MDA) and inflammatory cytokines (IL-1β, IL-6, TNF-α) decreased (p < 0.01). …”
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20503
H2AK119ub is bidirectionally dynamic within cis-regulatory elements during neurodevelopment.
Published 2025“…<b>(D)</b> Heatmaps depicting normalized H2AK119ub CUT&RUN data in the early and late cerebellum centered around loci with unchanged, increased or decreased H2AK119ub, as defined by DiffBind. …”
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20504
Table 1_Associations between gut microbiota and diet composition of three arid-adapted rodent species from the Inner Mongolia grassland.doc
Published 2025“…In contrast, the consumption of animal-based foods significantly decreased microbial diversity. This finding suggests a potential link between the host’s genetic background, dietary composition, and the gut microbiota.…”
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20505
Table 1_A population database analysis to describe the residual burden of varicella in Italy—a high vaccination coverage area—from 2004 to 2022.docx
Published 2025“…In the Veneto Region, following the implementation of VV in 2006, the IR significantly decreased by 20.5 annually (95% CI: −23.4, −17.5), ranging from 50.2 per 1,000 person-years in 2006 to 1.2 per 1,000 person-years in 2022.…”
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20506
Supplementary Material for: Alpinia galanga essential oil mitigates gentamycin-induced renal injury: in silico and in vivo studies
Published 2025“…Results: Network Pharmacology suggested Toll-like receptors 4 (TLR4), and Interleukin-1beta (IL-1β) as potential targets of Gal EO components in Genta induced renal toxicity. Gal EO significantly decreased Cr, uric acid, BUN, CysC, NGAL and Kim-1 and the urine albumin/creatinine ratio. …”
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20507
Data Sheet 1_Physical activity of moderate-intensity optimizes myocardial citrate cycle in a murine model of heart failure.pdf
Published 2025“…Interestingly, 8-sWR significantly decreased myocardial citrate content in the presence of unchanged myocardial [BCAAs], ETC proteins content and mtDNA copy number.…”
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20508
DataSheet1_Clinical associations of complement-activating collectins, collectin-10, collectin-11 and mannose-binding lectin in preterm neonates.pdf
Published 2024“…An important finding was the decreased concentrations of CL-10, CL-11 and MBL in respiratory distress syndrome (RDS). …”
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20509
Image2_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …”
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20510
DataSheet1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer...
Published 2024“…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …”
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20511
Image1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …”
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20512
Supplementary data.xlsx
Published 2025“…However, recent studies have indicated that the telomere length of somatic cells can be drastically decreased in the offspring receiving in vitrofertilization (IVF) therapy, however, the underlying molecular mechanism remains unknown. …”
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20513
TNC promotes bone regeneration via inflammatory macrophage
Published 2024“…Transplantation of macrophages derived from injured periosteum is able to rescue the decreased skeletal stem cells and impaired bone regeneration caused by TNC deficiency. …”
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20514
Glycogen synthase kinase 3 promotes the proliferation of porcine epidemic diarrhea virus by phosphorylating the nucleocapsid protein
Published 2025“…The phosphorylation level significantly decreased after mutation of threonine (Thr) to serine (Ser). …”
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20515
Image 2_ATG16L1 promotes cell migration and invasion in high glucose–induced retinal capillary endothelial cells.tif
Published 2025“…The migration ability and invasion rate of RCECs were significantly higher in the HG group than in the NG group but decreased markedly after transfection with ATG16L1 siRNA, compared with those in the control group (p < 0.01).…”
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20516
Image 1_ATG16L1 promotes cell migration and invasion in high glucose–induced retinal capillary endothelial cells.tif
Published 2025“…The migration ability and invasion rate of RCECs were significantly higher in the HG group than in the NG group but decreased markedly after transfection with ATG16L1 siRNA, compared with those in the control group (p < 0.01).…”
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20517
Data Sheet 1_Lethal and sublethal effects of chemical and bio-insecticides on Spodoptera frugiperda adults: new perspectives for “attract-and-kill” control strategies.pdf
Published 2025“…Sublethal exposure to chlorantraniliprole significantly reduced larval and pupal development durations, decreased pupal weights, and shortened adult longevity in the offspring, without significantly affecting larval mortality, pupation rate, or emergence rate. …”
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20518
Data Sheet 2_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf
Published 2025“…It ameliorated MAMs ultrastructure and function, enhancing CypD, MCU, Sig-1R, and NOGO-B expression while reducing IP3R2, GRP75, and VDAC1. in vitro, YQHX significantly increased viability, reduced oxygen-glucose deprivation-induced mPTP opening and Ca<sup>2+</sup> levels, upregulated CypD, MCU, Sig-1R, and NOGO-B, and downregulated IP3R2, GRP75, and VDAC1. …”
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20519
Data Sheet 1_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf
Published 2025“…It ameliorated MAMs ultrastructure and function, enhancing CypD, MCU, Sig-1R, and NOGO-B expression while reducing IP3R2, GRP75, and VDAC1. in vitro, YQHX significantly increased viability, reduced oxygen-glucose deprivation-induced mPTP opening and Ca<sup>2+</sup> levels, upregulated CypD, MCU, Sig-1R, and NOGO-B, and downregulated IP3R2, GRP75, and VDAC1. …”
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20520
Image1_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif
Published 2024“…The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”