Image1_Inhibition of CISD2 enhances sensitivity to doxorubicin in diffuse large B-cell lymphoma by regulating ferroptosis and ferritinophagy.JPEG by Chaofeng Zhang (845343)

“…Silencing CISD2 significantly reduced cell proliferation, increased iron accumulation, depleted glutathione (GSH), and elevated malondialdehyde (MDA) levels, alongside the accumulation of ROS and increased MMP. …”

Image2_Inhibition of CISD2 enhances sensitivity to doxorubicin in diffuse large B-cell lymphoma by regulating ferroptosis and ferritinophagy.JPEG by Chaofeng Zhang (845343)

“…Silencing CISD2 significantly reduced cell proliferation, increased iron accumulation, depleted glutathione (GSH), and elevated malondialdehyde (MDA) levels, alongside the accumulation of ROS and increased MMP. …”

Table 1_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.xlsx by Lillia A. Baird (10575941)

“…</p>Results<p>Low-dose, but not high-dose, tofacitinib significantly increased survival and delayed weight loss. …”

DataSheet1_Global burden of chronic kidney disease in adolescents and young adults, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.docx by Ping Sun (59933)

“…However, the global age-specific death rate significantly decreased from 2.96 (2.76, 3.15) to 2.86 (2.61, 3.11), and the age-specific DALY rate remained stable. …”

Integrating legumes into cropping systems enhances soil carbon and nitrogen content while reduces the soil carbon-to-nitrogen ratio: A global meta-analysis by Zhiqiang Lu (20145192)

“…Moreover, SOC and STN increased when legumes replaced fallow or gramineous soil, whereas SCN significantly decreased only when legumes replaced gramineous systems. …”

Supporting information Abou-Kandil et al. by Olaf Kniemeyer (8561361)

“…Deletion of <i>rtaA</i> did not significantly change the ergosterol content of <i>A. fumigatus</i>, but decreased fluorescence intensity of the sterol-binding stain filipin. …”

Data Sheet 1_Herbal essential oils improve growth, antioxidant response, and gene expression in Nile Tilapia fingerlings.pdf by Malik Khalafalaa (22225135)

“…Hematological parameters increased, while serum cholesterol and triglyceride levels decreased. …”

Data Sheet 1_Formononetin promotes porcine oocytes maturation and improves embryonic development by reducing oxidative stress.zip by Na Wang (193263)

“…Moreover, FMN significantly decreased autophagy and apoptosis levels in blastocyst cells, potentially via regulation of the Nrf2/Keap1 pathway. …”

Data Sheet 1_Preparation and characteristics of carboxymethyl cellulose-based films embedding cinnamon essential oil and their application on mutton preservation.pdf by Han Wang (254423)

“…When the CEO concentration was 1.5 g/L, the oxygen permeability of the film was the lowest, and mechanical properties were the highest. When the CEO increased, the thickness of the films increased, and the moisture absorption and water solubility of the film decreased. …”

DataSheet1_Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo.PDF by Huan Yu (140826)

“…</p>Results<p>In vitro experiments demonstrated that the survival rate of R28 cells after glutamate treatment dropped to 33.4%, while 10 μM baicalin significantly inhibited glutamate-induced damage in RGCs (P < 0.001) and enhanced cell viability through decreasing ROS levels, increasing antioxidant enzyme activity, and suppressing the expression of inflammatory factors iNOS, TNF-α, IL-6, and IL-1β (P < 0.001). …”

Data Sheet 1_BAM8-22 targets spinal MrgC receptors to modulate UPRmt activity in the mechanism of bone cancer pain.docx by Mingming Xie (20963636)

“…Additionally, the paw withdrawal mechanical threshold in BCP mice increased, while the number of spontaneous foot lifts decreased. …”

Image 2_Apolipoprotein C1 -317H1/H2 and the rs4420638 genetic variations and risk of gestational diabetes mellitus in Chinese women: a case-control study.jpeg by Wandi Ma (17295430)

“…H2 allele correlated with decreased levels of low-density lipoprotein cholesterol (LDL-C), apoB and lower atherogenic index (AI) in both groups, in addition to the GDM group also with lower total cholesterol (TC), whereas the G allele of rs4420638 correlated with increased triglyceride and decreased apoA1 levels.…”

DataSheet1_Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo.PDF by Huan Yu (140826)

“…</p>Results<p>In vitro experiments demonstrated that the survival rate of R28 cells after glutamate treatment dropped to 33.4%, while 10 μM baicalin significantly inhibited glutamate-induced damage in RGCs (P < 0.001) and enhanced cell viability through decreasing ROS levels, increasing antioxidant enzyme activity, and suppressing the expression of inflammatory factors iNOS, TNF-α, IL-6, and IL-1β (P < 0.001). …”

Image 1_Apolipoprotein C1 -317H1/H2 and the rs4420638 genetic variations and risk of gestational diabetes mellitus in Chinese women: a case-control study.jpeg by Wandi Ma (17295430)

“…H2 allele correlated with decreased levels of low-density lipoprotein cholesterol (LDL-C), apoB and lower atherogenic index (AI) in both groups, in addition to the GDM group also with lower total cholesterol (TC), whereas the G allele of rs4420638 correlated with increased triglyceride and decreased apoA1 levels.…”

DataSheet1_Identification of osmotic stress resistance mediated by MdKAI2 in apple.docx by Hongyang Guo (9466516)

“…KAR1, a highly active form of KAR, markedly promoted the root growth of Gala cultivar tissue culture‒generated plants, possibly through increases in ABA and TZR contents and decreases in the GA3 content. …”

DataSheet2_Identification of osmotic stress resistance mediated by MdKAI2 in apple.docx by Hongyang Guo (9466516)

“…KAR1, a highly active form of KAR, markedly promoted the root growth of Gala cultivar tissue culture‒generated plants, possibly through increases in ABA and TZR contents and decreases in the GA3 content. …”

Effect of TRPML1 on inflammation in lymphedema mice. by Lijie Yang (694492)

“…Compared with that of the SHAM group, the expression of IL-1β/IL-6/TGF-β1/col-1/vimentin/α-SMA genes in the WT group was significantly increased. Compared with that in the WT group, the expression of IL-1β/IL-6/TGF-β1/col-1/vimentin/α-SMA genes was significantly decreased in the TRPML1^−/− group (*<i>p</i> < 0.05, **<i>p</i> < 0.01, ***<i>p</i> < 0.001).…”

Data Sheet 1_Refinement of the novel tank diving test: toward standardized and robust analysis of anxiety-like behavior in zebrafish.docx by Takuro Shinkai (22518659)

“…Furthermore, we demonstrated that net-chasing during fish handling significantly increased the freezing time, suggesting the adoption of funnel-based transfers to reduce stress artifacts. …”

Data Sheet 1_The role of neutrophils and NETosis in lipopolysaccharide exacerbated asthmatic airway inflammation.docx by Qian Qian (45749)

“…Neutrophil-related markers like IL6, IL8, and neutrophil extracellular traps (NETs) were significantly elevated in this model. Inhibiting neutrophils production significantly improved airway inflammation and lung function. …”

Supplemental Materials by Ying Wang (15199117)

“…Compared to lean male mice, obese male mice had significantly increased accumulation of fluorescein-conjugated dextran in multiple organs, higher levels of soluble VE-cadherin, impaired systolic function with decreased ejection fraction post-AP and lipolysis. …”