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significant decrease » significantly increased (Expand Search)
significant fold » significant force (Expand Search), significant co (Expand Search), significant all (Expand Search)
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18941
Data Sheet 1_Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.zip
Published 2025“…Objective<p>Previous research has demonstrated that the hypoxic environment at high altitudes significantly alters the pharmacokinetics of many drugs, reducing their efficacy and increasing adverse effects. …”
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18942
Data Sheet 6_Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.zip
Published 2025“…Objective<p>Previous research has demonstrated that the hypoxic environment at high altitudes significantly alters the pharmacokinetics of many drugs, reducing their efficacy and increasing adverse effects. …”
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18943
Data Sheet 7_Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.zip
Published 2025“…Objective<p>Previous research has demonstrated that the hypoxic environment at high altitudes significantly alters the pharmacokinetics of many drugs, reducing their efficacy and increasing adverse effects. …”
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18944
Data Sheet 1_Polydatin combined with hawthorn flavonoids alleviate high fat diet induced atherosclerosis by remodeling the gut microbiota and glycolipid metabolism.pdf
Published 2025“…</p>Results<p>Polydatin combined with hawthorn flavonoids administration significantly reduced lipid and inflammatory cytokine levels, meanwhile, the atherosclerotic lesions in a high-fat diet-induced ApoE<sup>−/−</sup> mice were significantly decreased. …”
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18945
Table 1_The improvement effect of insoluble dietary fiber of Polygonatum sibiricum on hyperlipidemia in high-fat diet mice via gut microbiota and metabolites.docx
Published 2025“…In addition, PIDF supplements also decreased the ratio of Bacillota to Bacteroidota, increasing the relative abundance of Alistipes and Akkermansia. …”
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18946
Data Sheet 1_Desulfovibrio vulgaris exacerbates sepsis by inducing inflammation and oxidative stress in multiple organs.pdf
Published 2025“…Phosphorylation of MAPK and NF-κB pathways in peritoneal macrophages was significantly enhanced. Additionally, D. vulgaris amplified oxidative stress across multiple organs, as indicated by increased ROS levels and decreased antioxidant enzyme activity.…”
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18947
Graphical Abstract.
Published 2025“…Peak VO<sub>2</sub> (p < 0.001), MET (p < 0.001), oxygen pulse (p = 0.006), knee extensor (p < 0.001) and handgrip strength decreased significantly within CG (p = 0.009). MET (p < 0.001) and %handgrip strength increased significantly in ACG compared to AG and CG (p = 0.021). …”
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18948
PONE-Dataset.
Published 2025“…Peak VO<sub>2</sub> (p < 0.001), MET (p < 0.001), oxygen pulse (p = 0.006), knee extensor (p < 0.001) and handgrip strength decreased significantly within CG (p = 0.009). MET (p < 0.001) and %handgrip strength increased significantly in ACG compared to AG and CG (p = 0.021). …”
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18949
Demographic characteristics of groups.
Published 2025“…Peak VO<sub>2</sub> (p < 0.001), MET (p < 0.001), oxygen pulse (p = 0.006), knee extensor (p < 0.001) and handgrip strength decreased significantly within CG (p = 0.009). MET (p < 0.001) and %handgrip strength increased significantly in ACG compared to AG and CG (p = 0.021). …”
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18950
<b>Nonlinear and Sex-Specific Associations of Vitamin D Metabolites with Inflammatory Blood Markers in 455,000 Adults</b>
Published 2025“…Neutrophil counts were lowest at 25(OH)D levels of ~40–60 nmol/L and increased significantly at both lower and higher extremes (p < 0.001). …”
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18951
<b>Nonlinear and Sex-Specific Associations of Vitamin D Metabolites with Inflammatory Blood Markers in 455,000 Adults</b>Item
Published 2025“…Neutrophil counts were lowest at 25(OH)D levels of ~40–60 nmol/L and increased significantly at both lower and higher extremes (p < 0.001). …”
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18952
Table 1_Organic fertilizer in combination with zeolite enhanced maize yield with lower greenhouse gas emissions in sandy loam soil in North China.docx
Published 2025“…</p>Results<p>Results showed that, compared with the SF treatment, the ZOF treatment significantly increased yield by 14.72–23.61% in each of the 3 years, ZSF by 13.91–15.59% in 2022 and 2023, and OF by 16.92% in 2023. …”
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18953
Data Sheet 1_Virus-like particles containing the extracellular domain of G protein in combination with a CTL peptide of M2 elicit protection against respiratory syncytial virus inf...
Published 2025“…Compared with the UV-RSV control group, both G<sub>ECD</sub>/M2<sub>82-90</sub>-VLPs and G<sub>ECD</sub>-VLPs groups exhibited significantly increased Th1-type cytokine levels and decreased Th2-type cytokine concentrations (P<0.05, P<0.001). …”
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18954
Image 1_Subepicardial adipose genes contribute to the deterioration of heart failure preserved ejection fraction.tif
Published 2025“…Additionally, FOS, ALOX5 and OGN expressions were increased at follow up 1 year recurrence, while decreased at follow up 2 year recurrence. …”
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18955
Data Sheet 1_Subepicardial adipose genes contribute to the deterioration of heart failure preserved ejection fraction.pdf
Published 2025“…Additionally, FOS, ALOX5 and OGN expressions were increased at follow up 1 year recurrence, while decreased at follow up 2 year recurrence. …”
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18956
Image 2_Subepicardial adipose genes contribute to the deterioration of heart failure preserved ejection fraction.tiff
Published 2025“…Additionally, FOS, ALOX5 and OGN expressions were increased at follow up 1 year recurrence, while decreased at follow up 2 year recurrence. …”
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18957
Data Sheet 1_Bryostatin-1 enhances the proliferation and functionality of exhausted CD8+ T cells by upregulating MAP Kinase 11.docx
Published 2025“…</p>Results<p>We found that bryostatin-1 improved the expansion and decreased PD-1 expression of HIV-specific CD8+ T cells. …”
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18958
Table1_Mechanism of abscisic acid in promoting softening of postharvest ‘Docteur Jules Guyot’ pear (Pyrus communis L.).docx
Published 2024“…The contents of water-soluble pectin (WSP) and ionic-soluble pectin (ISP) increased, and covalent binding pectin (CBP) decreased under ABA treatment. …”
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18959
DataSheet1_Morphological, physiological, and biochemical responses of three different soybean (Glycine max L.) varieties under salinity stress conditions.docx
Published 2024“…The concentrations of chlorophyll a and b decreased with increasing salinity. In addition, salinity significantly increased leaf electrolyte leakage (EL), lipid peroxidation, proline accumulation, and phenol and flavonoid content. …”
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18960
Table2_Mechanism of abscisic acid in promoting softening of postharvest ‘Docteur Jules Guyot’ pear (Pyrus communis L.).xlsx
Published 2024“…The contents of water-soluble pectin (WSP) and ionic-soluble pectin (ISP) increased, and covalent binding pectin (CBP) decreased under ABA treatment. …”