بدائل البحث:
significant decrease » significantly increased (توسيع البحث)
significant new » significant non (توسيع البحث), significant genes (توسيع البحث), significant anti (توسيع البحث)
new decrease » nn decrease (توسيع البحث), we decrease (توسيع البحث), mean decrease (توسيع البحث)
significant decrease » significantly increased (توسيع البحث)
significant new » significant non (توسيع البحث), significant genes (توسيع البحث), significant anti (توسيع البحث)
new decrease » nn decrease (توسيع البحث), we decrease (توسيع البحث), mean decrease (توسيع البحث)
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20301
Table 2_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
منشور في 2025"…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…"
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20302
Image 1_Profiling of small RNAs derived from tomato brown rugose fruit virus in infected Solanum lycopersicum plants by deep sequencing.jpeg
منشور في 2025"…Seven potential target genes were selected for qRT-PCR analysis, confirming that their transcript accumulation significantly decreased in the leaves of tomato plants infected with ToBRFV. …"
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20303
Data Sheet 1_Menthone lowers H3K27ac levels to inhibit Fusarium proliferatum growth.docx
منشور في 2025"…</p>Results<p>This study demonstrated that menthone, the primary component of Mentha haplocalyx EO, exhibited notable antifungal activity against Fusarium proliferatum (EC50 = 6.099 mmol/L). The treatment significantly inhibited hyphal growth, reduced spore germination rates from 31.49 to 4.95%, decreased spore viability from 46.88 to 20.91%, and reduced spore production by a factor of 17.92 compared with the control group while simultaneously enhancing cell membrane permeability. …"
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20304
Table 2_Profiling of small RNAs derived from tomato brown rugose fruit virus in infected Solanum lycopersicum plants by deep sequencing.xls
منشور في 2025"…Seven potential target genes were selected for qRT-PCR analysis, confirming that their transcript accumulation significantly decreased in the leaves of tomato plants infected with ToBRFV. …"
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20305
Table 4_Mechanism of Huaiqihuang (HQH) against cyclophosphamide (CYP)-induced hippocampal neurotoxicity based on network pharmacology, molecular docking and experimental verificati...
منشور في 2025"…Experimental validation using Western blot confirmed that HQH significantly decreased the protein expression of TNF, HSP90AA1, TP53, and MAPK1 in hippocampal tissues.…"
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20306
Betulinic acid protects SH-SY5Y cells exposed to lipopolysaccharide and ferrous sulfate through p38MAPK/NF-κB/GPX4/Nrf2/keap-1/HO-1 signaling axis
منشور في 2025"…Furthermore, LPS and FeSO<sub>4</sub> significantly increased the expression of IL-6, TNF-α, and phosphorylation of p38, pMAPK, and pNFkB in the cells. …"
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20307
Supplementary Material for: Words versus strands: Reliability and stability of concordance rates of self-reported and hair-analyzed substance use of young adults over time
منشور في 2024"…Hair analysis-derived 3-month prevalence rates of cocaine (9%/23%) and ketamine (2%/6%) strongly increased over time, while decreasing for codeine (11%/8%). …"
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20308
Optimisation of read depth, DNA quantity, and unique alternate observation threshold.
منشور في 2025"…I: The CV of variant size quantitation across independent replicates, which displayed a strong negative correlation to variant size (dotted lines indicate 95% confidence interval). J-L: Increasing unique alternative observation (UAO) thresholds for variant calls increased detection rate of rare variants (J), but markedly decreased the number of variants passing the threshold (K) and therefore reduced detection of true positive variants in reference standards (L). …"
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20309
Data Sheet 1_Effects of practical models of low-volume high-intensity interval training on glycemic control and insulin resistance in adults: a systematic review and meta-analysis...
منشور في 2025"…HOMA-IR also decreased with every additional minute of weekly interval duration (β;=-0.06; 95%CI: -0.08 to -0.04; p<0.001). …"
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20310
The Effect of Chronic Stress on Apoptosis Regulation and Oncogenesis Evolution: A Theoretical Approach.
منشور في 2025"…</p><p dir="ltr">- Somatisation and Organ Response: Chronic stress is frequently somatised by increased autonomic nervous system activity, which causes malfunction in important organs, increases inflammation, and increases the risk of neoplastic diseases.…"
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20311
Impact of acute binge-like ethanol exposure during the third-trimester equivalent on subicular interneurons in mice
منشور في 2025"…Adolescent neuronal density was significantly decreased in exposed males’ distal dorsal subiculum (<i>p</i> < .0001, g = −0.8). …"
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20312
Additional file 1 of MDM2-amplified esophageal adenocarcinomas exhibit an activated metabolic and immunosuppressive phenotype with multiple potential therapeutic targets
منشور في 2025"…Volcano plot of all detected proteins comparing the proteome of neoadjuvantly treated MDM2-amplified and non-amplified tumors. Grey: not significantly different expressed, blue: significantly decreased expression in neoadjuvantly treated MDM2-amplified tumors, red: significantly increased expression in neoadjuvantly treated MDM2-amplified tumors. …"
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20313
Prognostic indicators and survival rates in vulvar cancer: insights from a retrospective study
منشور في 2025"…Additionally, a tumour size exceeding 4 cm in diameter was significantly linked with decreased OS (<i>p</i> = .001). …"
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20314
Table 1_Widely conserved miRNAs in buffalo milk extracellular vesicles survive gastrointestinal digestion and potentially target neural and immunomodulatory contexts.docx
منشور في 2025"…The miRNA cargo exhibited a similar pattern, except miR-141-3p, miR-153-3p, both increased slightly, and miR-223-3p, which increased substantially; miR-148a-3p, which decreased; and miR-33a-3p, which was no longer detectable after digestion. …"
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20315
Table 2_Widely conserved miRNAs in buffalo milk extracellular vesicles survive gastrointestinal digestion and potentially target neural and immunomodulatory contexts.docx
منشور في 2025"…The miRNA cargo exhibited a similar pattern, except miR-141-3p, miR-153-3p, both increased slightly, and miR-223-3p, which increased substantially; miR-148a-3p, which decreased; and miR-33a-3p, which was no longer detectable after digestion. …"
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20316
Data Sheet 1_Effects of Th1/Th17 and Th2 cytokines on lipid metabolism in differentiated keratinocytes.zip
منشور في 2025"…Th1/Th17 cytokines significantly inhibited the high calcium-induced synthesis of phospholipids (PCs, PEs, SMs), and short-chain ceramides, while the synthesis of ceramides with medium to long carbon chains was upregulated. …"
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20317
Phage–antibiotic interactions are determined by the antibiotic, not the phage.
منشور في 2025"…While the phage amplification rate increases with nitrofurantoin (synergy), it decreases with doxycycline (antagonism). …"
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20318
Table 1_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx
منشور في 2025"…Immune Microenvironment Profiling linked key genes to altered placental immune cell populations. qRT-PCR confirmed that GLUL and NCL expression decreased and DDX28 and RIOK1 expression increased in clinical placental samples of preeclampsia group.…"
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20319
Supplementary file 1_Single-cell transcriptomics identifies FOSL1-regulated IGFBP3+ melanoma subtype as a neuro-immunoregulatory signaling hub facilitating tumor progression.docx
منشور في 2025"…The C2 subtype was strongly linked with FOSL1 expression, which may affect gene transcription and illness progression. FOSL1 knockdown significantly increased apoptosis and decreased melanoma cell motility and proliferation in vitro.…"
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20320
Image 1_A metagenome-wide association study of gut microbiota in hepatitis B virus-related cirrhosis in northwest China.tif
منشور في 2025"…</p>Conclusion<p>HBV-LC patients in Northwest China exhibit altered clinical indicators, gut microbial composition (reduced diversity, increased opportunistic pathogens, decreased beneficial species), and metabolic function. …"