Table 1_LpxR and PagL expression in live attenuated auxotrophic Pseudomonas aeruginosa vaccines modulates lipid A reactogenicity in vitro while preserving immunogenicity.docx by Miriam Moscoso (345679)

“…Both mutant strains showed decreased TLR4 activation in vitro as compared to the wild type. …”

Image 3_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..jpeg by Felicia Menicucci (7495508)

“…</p>Results<p>The PS II efficiency decreased in response to red LEDs treatment only. The highest levels of polyphenol and chlorophyll content were registered in response to blue LEDs exposure in both cultivars. …”

Data Sheet 1_Dynamic stability of gut microbiota in elite volleyball athletes: microbial adaptations during training, competition and recovery.pdf by Junior Carlone (22173565)

“…The Firmicutes/Bacteroidetes ratio fluctuated in response to training intensity and competition 6:1 during T0 and T1, decreasing to 3:1 during T2 and returning to 5:1 during T3. …”

Data Sheet 2_Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway.docx by Xin Zhou (54275)

“…Mechanistically, rutin demonstrated dual suppression: 1) inhibiting cGAS-STING activation through decreased expression of cGAS, STING, and phosphorylation of TBK1/IRF3 (P<0.05), and 2) attenuating NLRP3-mediated pyroptosis via downregulation of NLRP3-ASC-caspase1-GSDMD signaling (P<0.05). …”

Table 2_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx by Wenjun Wang (314231)

“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”

Data Sheet 1_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.xlsx by Christina Stevens (9737867)

“…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. However, only age, hindlimb joint pain, and hindlimb muscle atrophy had statistically significant effects on physical activity.…”

Table 11_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx by Wenjun Wang (314231)

“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”

Table 1_Brown adipocyte exosome - derived C22:6 inhibits the IL-1β signaling pathway to alleviate rheumatoid arthritis.docx by Rui Jiang (264894)

“…In the CIA mouse model, transdermal application of hcBAC-exos led to notable decreases in ankle swelling and the serum levels of IL-1β and TNFα (P < 0.5). …”

Data Sheet 5_CD44 knockdown alters miRNA expression and their target genes in colon cancer.zip by Diana Maltseva (11678641)

“…Collectively, these effects decreased the metastatic potential of the CRC xenograft tumors under investigation. …”

Table 1_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..docx by Felicia Menicucci (7495508)

“…</p>Results<p>The PS II efficiency decreased in response to red LEDs treatment only. The highest levels of polyphenol and chlorophyll content were registered in response to blue LEDs exposure in both cultivars. …”

Table 7_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx by Wenjun Wang (314231)

“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”

Table 1_An alternative structured weight management protocol to rapid weight loss in mixed martial arts: a prospective interventional study of pre-competition weight management str... by Clóvis Albuquerque Maurício (22389121)

“…Starting 7 days before the weigh-in, athletes consumed 7 liters of fluids per day, with intake gradually decreasing. On the day before the weigh-in, they consumed only 0.5 liters. …”

Image 1_Lower hippocampal volumes at baseline are associated with higher volume loss in healthy elderly.png by Vivian Schultz (17379235)

“…</p>Results<p>Hippocampal volumes decreased from baseline to follow-up [mean APC (SD): right −1.34% (0.94), left: −1.79% (1.00)]. …”

Table 2_Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia.docx by Yu Zhou (89766)

“…Extending these findings in vivo, MK-801–treated mice exhibited behavioral and neuronal deficits, reduced ATP5A fluorescence intensity, and decreased ATP concentrations; expression of all four hub genes was significantly altered, with three (MALAT1, PPIL3, and ITM2A) concordant with transcriptomic results. …”

Renal Tubule-Specific Angiotensinogen Deletion Attenuates SGLT2 Expression and Ameliorates Diabetic Kidney Disease in Murine Models of Type 1 Diabetes by Wen-Xia Yang (20485041)

“…Urinary Agt, Angiotensin II (Ang II) and oxidative stress were decreased in <a href="" target="_blank">Akita RT-<i>Agt</i>^<em>-/-</em> </a>mice cf. …”

Table 1_Research on the effect of LAMP1 in the development and progression of ccRCC and its potential mechanism with LC3C-mediated autophagy.docx by Xiongbao Wang (12508462)

“…LAMP1 expression remained unchanged during autophagy modulation but decreased with LC3C knockdown and vice versa. Notably, VHL(+) cells expressed less LAMP1 than VHL(-) cells.…”

Data Sheet 1_Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway.docx by Xin Zhou (54275)

“…Mechanistically, rutin demonstrated dual suppression: 1) inhibiting cGAS-STING activation through decreased expression of cGAS, STING, and phosphorylation of TBK1/IRF3 (P<0.05), and 2) attenuating NLRP3-mediated pyroptosis via downregulation of NLRP3-ASC-caspase1-GSDMD signaling (P<0.05). …”

Image1_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tiff by Khushbu Priya (11863559)

“…In PIL mouse model, DW and IW treatments reduced NETosis, ROS generation, as evidenced by decreased NET-associated protein expression in vital organs.…”

Supplementary file 1_Exploring dupilumab for asthma: from mechanistic insights to clinical outcomes, safety, and cost-effectiveness.docx by Omar Z. Ameer (8900039)

“…Clinical trials have demonstrated significant reductions in asthma exacerbation rates, improvements in forced expiratory volume in one second (FEV₁), and decreased oral corticosteroid (OCS) dependence in adults and children with moderate-to-severe asthma. …”

Data Sheet 1_Reduced hemolytic complement activity in the classical pathway (CH50) is a risk factor for poor clinical outcomes of patients with infections: a retrospective analysis... by Hiroyuki Koami (3878434)

“…</p>Results<p>Of 2,726 patients who met the inclusion criteria, logistic regression models demonstrated that decreased CH50 is a significant predictor of 180-day mortality (OR: 0.98-0.99). …”