Effect of ex vivo treatment with rhTGFβ1 or a TGFβ1 inhibitor on monocyte responses to rgE stimulation. Monocytes and NK cells purified from PBMC collected from 10 RZV recipients (demographics in S4 Table) before vaccination (D0) and 90 days post-vaccination (D90) were combined ex vivo and stimulated with VZV-rgE. A subset of D0 monocyte & NK cocultures was also treated with the TGFβ1 inhibitor LY (D0 LY), and a subset of D90 cocultures were supplemented with rhTGFβ1. The graph shows individual data points, means and p values calculated by Friedman test for repeated measures with FDR correction. LY treatment of cells collected on D0 significantly increased their activation to levels similar to D90. Conversely, treatment of D90 cells with rhTGFβ1 significantly decreased their activation to levels similar to D0. حسب Michael J. Johnson (5818168)

"…Conversely, treatment of D90 cells with rhTGFβ1 significantly decreased their activation to levels similar to D0.…"

Cohort characteristics. حسب Vincent Pey (21433304)

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Quantification of bacterial adhesion revealed a significant decrease in the adhesion of <i>S. aureus</i>, <i>S. epidermidis</i>, and <i>P. aeruginosa</i> on blotted corneas of mice treated with 0.5% bupivacaine (BUP) combined with topical (TOP) application, following subconjunctival injection (SCI) of CGRP, 24 hours before the final BUP treatment (day 14) and again one hour prior to the final bupivacaine injection on day 15. حسب Ananya Datta (19932144)

A, Uncropped image of gel in Fig 1B. حسب Tomokazu Yamaguchi (8284989)

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Cnot4 haploinsufficiency impairs rosiglitazone-induced transcriptional activity of PPAR حسب Tomokazu Yamaguchi (8284989)

الموضوعات:

Cnot4 mediates differentiation into adipocytes from mouse embryonic fibroblasts. حسب Tomokazu Yamaguchi (8284989)

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Cnot4 heterozygosity confers resistance to high fat diet-induced obesity. حسب Tomokazu Yamaguchi (8284989)

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Cnot4 Het does not affect mRNA expression of metabolic genes as well as serum lipid levels or glucose tolerance. حسب Tomokazu Yamaguchi (8284989)

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Cnot4 homozygous knockout mice are embryonic lethal. حسب Tomokazu Yamaguchi (8284989)

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Trends in full immunization coverage among two-year-olds in Sierra Leone, 2008-2019. حسب Umaru Sesay (18982263)

الموضوعات:

Inequalities in full immunization coverage among two-year-olds in Sierra Leone, 2008-2019. حسب Umaru Sesay (18982263)

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Trends in full immunization coverage among two-year-olds in Sierra Leone, 2008-2019. حسب Umaru Sesay (18982263)

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Adult <i>Shroom3</i>^<i>+</i>^<i>/Gt</i> hearts show decreased cardiomyocyte cross-sectional area. حسب Jennifer L. Carleton (22208916)

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Data Sheet 1_Prehospital tranexamic acid decreases early mortality in trauma patients: a systematic review and meta-analysis.docx حسب Yi Li (1144)

"…</p>Conclusion<p>Prehospital TXA decreases early (24-h) mortality in trauma patients without a significant increase in the risk of VTE and other complications, and further studies are still needed to improve and optimize its management strategy.…"

Hypothesis 3: The mean difference between “Class 1” (a school attack happens within <i>k</i> kms. of a given school) and “Class 0” (no school attack happens within <i>k</i> kms. of... حسب Lirika Sola (21560710)

S2 File - Factors influencing effective decrease of controlled attenuation parameters in metabolic-associated steatotic liver disease: A multilevel linear regression analysis at Va... حسب Sonsawan Sangprasert (22772538)

Data Sheet 1_Decreased brain-derived neurotrophic factor expression in chronic kidney disease: integrated clinical and experimental evidence.docx حسب Juan Chen (61123)

"…</p>Conclusion<p>This study integrated meta-analysis, murine model validation, and single-cell transcriptomic profiling to demonstrate a significant reduction of BDNF in CKD. Furthermore, renal BDNF expression decreased locally, predominantly originating from proximal tubule cells, macrophages, and podocytes, possibly epigenetically inhibited by the upregulation of lnc RNA Bdnf-as.…"

Image1_Association between mental health and male fertility: depression, rather than anxiety, is linked to decreased semen quality.tif حسب Yi Zhang (9093)

"…</p>Results<p>Status of depression was negatively associated with semen quality parameters, whereas no statistically significant association was recognized between anxiety and semen quality except that sperm concentration was decreased by 25.60 (95% CI, 1.226 to 49.965, P=0.040) ×10⁶/ml in moderate to severe anxiety group referring to normal group. …"

This is the raw data used for this study. حسب James M. Friedman (22522150)

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Pre-operative versus post-operative symptoms. حسب James M. Friedman (22522150)

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