Hypoxia-inducible factor-1α promotes tubulointerstitial fibrosis via the upregulation of <i>Muc4</i> by Zhong-Tang Li (21183172)

“…Then, the results of transcriptomic analysis and <i>in vivo</i> and <i>in vitro</i> experiments revealed that expression of Mucin 4 (MUC4) was significantly decreased at the transcriptional and protein levels in tubular HIF-1α-knockout mice. …”

Data_Sheet_2_Association of glymphatic system dysfunction with cognitive impairment in temporal lobe epilepsy.docx by Jiajia Wang (157207)

“…Linear regression analyses showed that increased CPV and decreased DTI-ALPS index were independent risk factors for semantic fluency impairment (all p < 0.05). …”

Table_2_Association of glymphatic system dysfunction with cognitive impairment in temporal lobe epilepsy.docx by Jiajia Wang (157207)

“…Linear regression analyses showed that increased CPV and decreased DTI-ALPS index were independent risk factors for semantic fluency impairment (all p < 0.05). …”

Table_3_Association of glymphatic system dysfunction with cognitive impairment in temporal lobe epilepsy.docx by Jiajia Wang (157207)

“…Linear regression analyses showed that increased CPV and decreased DTI-ALPS index were independent risk factors for semantic fluency impairment (all p < 0.05). …”

Data Sheet 1_The effects and mechanism of urease inhibitor and its combination with nitrification inhibitor on nitrous oxide emission across four soil types.docx by Churong Liu (11174070)

“…<p>Nitrogen (N) fertilization is essential for ensuring crop productivity, while excessive N application significantly increases greenhouse gases (GHGs) emissions, particularly nitrous oxide (N₂O). …”

Table_1_Association of glymphatic system dysfunction with cognitive impairment in temporal lobe epilepsy.docx by Jiajia Wang (157207)

“…Linear regression analyses showed that increased CPV and decreased DTI-ALPS index were independent risk factors for semantic fluency impairment (all p < 0.05). …”

Data_Sheet_1_Association of glymphatic system dysfunction with cognitive impairment in temporal lobe epilepsy.docx by Jiajia Wang (157207)

“…Linear regression analyses showed that increased CPV and decreased DTI-ALPS index were independent risk factors for semantic fluency impairment (all p < 0.05). …”

Cows' BHB impacts on calf BAT growth and metabolic health by Yanting Chen (20532152)

“…The results showed that although high BHB levels had no effect on calf birth weight or growth, they significantly impaired glucose sensitivity, increased stress genes and decreased brown adipose tissue mass, thermogenic proteins and mitochondrial density. …”

Data Sheet 1_Biochar and Bacillus subtilis co-drive dryland soil microbial community and enzyme responses.doc by Tao Zheng (146941)

“…Meanwhile, except for the YJ treatment, the richness of the fungal community decreased, while the diversity index increased. The experimental results showed that the application of rapeseed straw biochar or the compound microbial inoculant alone significantly increased soil urease activity, reaching 40.34 µg of NH⁺₄-N g⁻¹ of soil h⁻¹ and 40.29 µg of NH⁺₄-N g⁻¹ of soil h⁻¹ at the end of the incubation period, respectively.…”

Data Sheet 1_Serum metabolomics reveal the mechanisms by which fermented brewer’s spent grains promote intestinal development in white-feathered broilers.zip by Yuanfeng Li (217864)

“…Specifically, key DEMs involved in amino acid metabolism included significantly increased phenylalanine levels and decreased 4-HPA and 3-HPA levels (p < 0.05). …”

DataSheet1_Apolipoprotein A-I attenuates peritoneal fibrosis associated with peritoneal dialysis by inhibiting oxidative stress and inflammation.ZIP by Jing Lu (120666)

“…In this study, by analyzing PD patients (n = 81), we found that decreased apoA/HDL-C ratio is significantly associated with rapid decline in peritoneal function. …”

Supplementary file 1_First exposure to second-generation antipsychotics alters gut microbiota and metabolic profiles in patients with glucose-lipid metabolism disorders.docx by Yuexia Wu (10755903)

“…</p>Results<p>Firstly, Gut microbial diversity differed significantly between groups. At genus level, the abundances of Escherichia and Bifidobacterium were increased significantly in the post-medication patients, while the abundances of Faecalibacterium and Blautia were decreased. …”

Image 1_Insights into the alteration of vaginal microbiota and metabolites in pregnant woman with preterm delivery: prospective cohort study.tif by Lihua Wang (14548)

“…In addition, vaginal metabolomics-based LC-Orbitrap-MS/MS revealed that the contents of 2-Piperidone, Melphalan, N-acetylputrescine, Obatoclax, Eurostoside, Pregnanediol 3-O-glucuronide, O-Phospho-L-serine, 1-Kestose and N-arachidonylglycine were significantly decreased in the PrPG group compared with the PrTG group, while Acenocoumarol, Isopyrazam, Pentosidine, hexose, 7-Hydroxymitragynine, PE, Tamoxifen and 1-Deoxynojirimycin contents were significantly increased. …”

Supplementary file 1_Ecosystem carbon storage and carbon metabolizing microorganisms in three types of grasslands on the Qinghai-Tibet Plateau.docx by Qian Liu (135614)

“…The relative abundance of carbon-fixing microorganisms Thiobacillus, Mesorhizobium, Azospirillum, and Methylibium significantly increased grassland carbon storage, while the relative abundance of chitinase-producing microorganisms Cellulomonas and Stenotrophomonas significantly decreased it.…”

Table 1_Insights into the alteration of vaginal microbiota and metabolites in pregnant woman with preterm delivery: prospective cohort study.docx by Lihua Wang (14548)

“…In addition, vaginal metabolomics-based LC-Orbitrap-MS/MS revealed that the contents of 2-Piperidone, Melphalan, N-acetylputrescine, Obatoclax, Eurostoside, Pregnanediol 3-O-glucuronide, O-Phospho-L-serine, 1-Kestose and N-arachidonylglycine were significantly decreased in the PrPG group compared with the PrTG group, while Acenocoumarol, Isopyrazam, Pentosidine, hexose, 7-Hydroxymitragynine, PE, Tamoxifen and 1-Deoxynojirimycin contents were significantly increased. …”

Identification of Alzheimer’s disease susceptibility genes by the integration of genomics and transcriptomics by Chenghong OuYang (13521682)

“…Through Mendelian randomization (MR) analysis, it was found that the risk of AD was significantly increased when VASP expression increased (OR = 0.1.046), while the risk of AD was significantly decreased when SURF2 (OR = 0.897) and TARBP1(OR = 0.920) expression increased. …”

Supplementary file 1_Association between olfactory dysfunction and gustatory dysfunction: evidence from the National Health and Nutrition Examination Survey.docx by Yi Yang (116183)

“…Similarly, the questionnaire data revealed that OD significantly increased the odds of GD. However, hyposmia OD decreased the odds of hypogeusia GD using the tongue-tip taste measurement.…”

Image2_Overexpression of vacuolar H+-pyrophosphatase from a recretohalophyte Reaumuria trigyna enhances vegetative growth and salt tolerance in transgenic Arabidopsis thaliana.tif by Ningning Li (566420)

“…Catalase enzyme activity, proline content, relative water content, and soluble sugar content were significantly increased in transgenic Arabidopsis under salt stresses, but the malondialdehyde content was dramatically decreased. …”

Image1_Overexpression of vacuolar H+-pyrophosphatase from a recretohalophyte Reaumuria trigyna enhances vegetative growth and salt tolerance in transgenic Arabidopsis thaliana.tif by Ningning Li (566420)

“…Catalase enzyme activity, proline content, relative water content, and soluble sugar content were significantly increased in transgenic Arabidopsis under salt stresses, but the malondialdehyde content was dramatically decreased. …”

Table 2_Prognostic alternative mRNA splicing in lung adenocarcinoma.xlsx by Panke Su (22636301)

“…High-risk patients, identified by the signature, showed significantly decreased stromal, immune, and combined scores; increased tumor purity (P< 0.001); a reduced prevalence of various immune cell types; diminished immune cell activity; and decreased expression of immune checkpoint genes. …”