Image 2_Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics.tif by Asma Bibi (12057986)

“…The KEGG enrichment analysis of serum and brain samples showed that amino acid metabolism pathways, such as tryptophan metabolism, threonine metabolism, serotonergic synapsis, methionine metabolism, and neuroactive ligand-receptor interaction, were significantly decreased in antibiotic-treated mice. Our study demonstrates that long-term antibiotic use induces gut dysbiosis and alters metabolic responses, leading to the dysregulation of brain signaling molecules and anxiety-like behavior. …”

Image 4_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.jpeg by Dang Li (16400478)

“…<p>Keloid scarring is a fibroproliferative disease of the skin, which can significantly impact one’s quality of life through cosmetic concerns, physical discomfort (itchy; painful), restricted movement, and psychological distress. …”

Data_Sheet_1_miR-124 Alleviates Ischemic Stroke-Induced Neuronal Death by Targeting DAPK1 in Mice.docx by Yan Shi (166398)

“…</p>Results<p>In vivo and in vitro results demonstrated that levels of miR-124 were significantly decreased following stroke, whereas changes in death-associated protein kinase 1 (DAPK1) levels exhibited the converse pattern. …”

Table 1_Autophagy crosstalk with the immune microenvironment in chronic myeloid leukemia and serves as a biomarker for diagnosis and progression.xlsx by Fangmin Zhong (17415318)

“…</p>Results<p>Compared with normal samples, CML samples had significantly lower autophagy scores and more downregulated ARGs. …”

Table 1_Associations between systemic inflammatory indices and the risk of renal function decline in patients with type 2 diabetes mellitus: a retrospective cohort study.docx by Zhi Shang (4849129)

“…Renal function decline was defined as an estimated glomerular filtration rate decreasing by ≥ 40% from baseline. All participants were categorized into tertiles according to the systemic inflammatory indices. …”

Data Sheet 1_Effect of music therapy on children with autism spectrum disorders in the Chinese population: a systematic review and meta-analysis.docx by Yajing Yang (2105431)

“…The results showed that MT significantly decreased the total ATEC (autism treatment evaluation checklist) score (SMD = -2.52, 95% CI: -3.69 ~ -1.35, P < 0.001), ABC (autism behavior checklist) (SMD = -1.07, 95% CI: -1.52 ~ -0.61, P < 0.001), and CARS (childhood autism rating scale) score (SMD = -1.50, 95% CI: -2.26 ~ -0.74, P < 0.001). …”

Data Sheet 1_Higher soil nitrous oxide production in landscape depressions linked to soil and hydrological legacy effects.docx by Yujia Liu (318262)

“…Depression soils exhibited 3,000- and 4,000-fold higher 16S rRNA and nosZ clade I abundances, respectively, compared to upland soils. Cu addition significantly decreased 16S rRNA abundance, eliminated AOB amoA in upland soils, and slightly reduced the tested gene abundances in depression soils. …”

Data Sheet 1_Iron modulates barrier integrity and stem cell function of small intestine during experimental colitis.docx by Shubin Wang (3105348)

“…</p>Results<p>It was shown that during DSS-induced colitis, small intestine underwent a serious injury process, including dysregulated integrity and decreased proliferation of ISCs. Iron overload significantly exacerbated intestinal injury in tissues, epithelial cell line, and intestinal organoids. …”

Data Sheet 1_Factors associated with cognitive flexibility in people with opioid-use disorder: a pilot study.docx by Paul S. Regier (8277792)

“…Impulsiveness, social function, and depressive symptoms were highly inter-related; however, only higher impulsiveness (r = -.48, p = 0.006) and more social impairment (r = -.47, p = 0.007) significantly correlated with decreased CET (but not n-Back) performance. …”

Data Sheet 1_Reduction of orexin-expressing neurons and a unique sleep phenotype in the Tg-SwDI mouse model of Alzheimer’s disease.pdf by Yan Wu (70890)

“…<p>Sleep disturbances are common in Alzheimer’s disease (AD) and AD-related dementia (ADRD). We performed a sleep study on Tg-SwDI mice, a cerebral amyloid angiopathy (CAA) model, and age-matched wild-type (WT) control mice. …”

Initial transport rate of [³H]-hypoxanthine of PhZ mutants (V%). by Mariana Barraco-Vega (19996318)

“…Mutants with measurements equivalent to those obtained with the ΔZAC strain are marked in red; mutants with decreased hypoxanthine uptake, equivalent to or higher than PhZwt, are indicated in blue, black or green, respectively. …”

Image 1_Exogenous prostaglandin D2 as a modulator in bovine endometritis: implications for reducing antibiotic use in dairy cattle.pdf by Xiaolin Yang (276496)

“…Introduction<p>Bovine endometritis is a common postpartum uterine infection that significantly impacts the health and production performance of dairy cows, leading to economic losses for farms. …”

Osseointegration of an innovative functionally gradient biomimetic scaffold based on Voronoi-Tessellation for the design of orthopaedic implants by Yuzhu Wang (845659)

“…The results showed that the gradient structure designed by this method had decreasing thickness and pore size from top to bottom. …”

The effect of cognitive behavioral therapy-based psychoeducation on substance abuse proclivity in adolescent smokers by Behiye Dilmen Bayar (19133390)

“…The SAPS total score average of the individuals in the experimental group decreased after psychoeducation compared to before psychoeducation. …”

Data Sheet 1_Alpine steppe vegetation communities are more sensitive to plateau pika disturbance than alpine meadows.docx by Rui Hua (127074)

“…</p>Results<p>The results showed that the alpine steppe was more sensitive to pika disturbance, with significant decreases in biomass, vegetation height, and coverage even at low disturbance levels. …”

<b>Two therapeutic approaches for vancomycin-induced acute kidney injury: urinary acidification or inhibition of organic anion transporters with probenecid</b> by Thibault Le Moulec (20854373)

“…Urinary acidification decreased plasma urea and improved histological scores of acute tubular necrosis (ATN) and cast formation on the third day. …”

Light avoidance requires the cGMP-dependent pathway in <i>P</i>. <i>pacificus</i>. by Kenichi Nakayama (2354653)

“…<p>(A) Blue light avoidance assay for light-unresponsive mutants that were isolated by forward genetic screening. These mutants had decreased light-induced avoidance response. (B) List of predicted causal genes. …”

Data Sheet 1_A multimodal approach for establishing ACTL6A and ERCC1 as chemoresistance genes in locally advanced head and neck cancer.docx by Raushan Kumar Chaudhary (15664043)

“…The median expressions of ERCC1 were significantly increased (p < 0.001) after 50% (0.19) and 100% CRT (0.23) compared to the baseline value (0.14), whereas ACTL6A expression decreased from 4.77 to 3.87 after 50% CRT (p < 0.05) and increased to 5.43 after 100% CRT. …”

Effect of curcumin on methotrexate-induced ovarian damage and follicle reserve in rats: the role of PARP-1 and P53 by Mete Keçeci (20479508)

“…In the MTX+Cur group, atretic follicle count decreased (<i>p</i> < 0,05), however, primordial follicle count increased (<i>p</i> < 0,01). …”

Experiences communicating in noise with aphasia (Harmon et al., 2024) by Tyson G. Harmon (11450904)

“…</p><p dir="ltr"><b>Results: </b>Quantitative findings showed that people with aphasia reported significantly greater perceived effort and stress than controls. …”