Determinants of lipid lowering therapy intensification in very high risk patients with dyslipidaemia eligible for PCSK9 monoclonal antibodies: 1-year outcomes of the PERI-DYS study by Klaus G. Parhofer (12280424)

“…</p> <p>Among 1565 patients, LDL-C levels decreased from 91.0 mg/dL at baseline to 73.5 mg/dL at 6 months and 71.5 mg/dL at 12 months. …”

Image1_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.tif by Chao Bai (4428472)

“…Objective<p>Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. …”

Evaluating the effectiveness of safety countermeasures at highway–railway grade crossing based on a machine learning framework by Mohammadali Zayandehroodi (19746176)

“…The CMF results demonstrated that bells achieved superior safety compared to other countermeasures in clusters with sharper track angles and high maximum train speeds. Implementing bells decreased collisions across Clusters 1 and 4, with reductions of 53% (CMF = 0.47) and 46% (CMF = 0.54), respectively.…”

Soil plant available silicon from a bamboo forest on karst mountain in southwest China differs between wet and dry seasons by Bin Xu (10691)

“…The citric-Si content of soils and drip water Si was in the range of 24.6–164 mg·kg⁻¹ and 3.63–13.6 mg·kg⁻¹, respectively, and decreased in the following order: A and AB horizon, O horizon, and drip water. …”

Data Sheet 1_Radiomics reveals the biological basis for non-small cell lung cancer prognostic stratification by reflecting tumor immune microenvironment heterogeneity.docx by Qing Huang (240196)

“…Immune microenvironment profiling showed significantly reduced immune scores and decreased proportions of naive B cells in high-risk patients, indicating impaired immune activity. …”

<b>Precursor and Mature miRNA Sequences from the Hepatopancreas of Macrobrachium rosenbergii under Low-Temperature Stress</b> by jinlin gong (21467675)

“…The prawns were housed in a 4 m² indoor tank, where water temperature was gradually decreased from 26 °C to 0 °C at a rate of approximately 1 °C every 4 hours by incremental addition of ice. …”

Table 1_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.docx by Yi Shen (152956)

“…</p>Results<p>In the multivariable logistical regression analysis, maintenance of CRF was significantly and inversely associated with PAA, demonstrating a decreased risk of 42% in the high CRF group [OR (95% CI): 0.58 (0.36, 0.96), p = 0.033]. …”

Table 1_Perception of health and illness and quality of life after total thyroidectomy for differentiated thyroid carcinoma: the PERSAM study.docx by Elena Groff (7446932)

“…Mental health: more information to patients decreases the degree of stress and promotes ‘positive’ emotions. …”

Image 1_The effects of antioxidant supplementation on pain, oxidative stress markers, and clinical pregnancy rate in women with endometriosis: a systematic review and meta-analysis... by Yuchan Zhong (22518395)

“…The results showed that antioxidant supplementation significantly alleviated pelvic pain (continuous outcomes: SMD = −2.68; p < 0.00001; binary outcomes: RR = 9.31; p < 0.0001), dysmenorrhea (SMD = −1.77; p = 0.01; RR = 2.39; p = 0.03), and dyspareunia (SMD = −2.33; p = 0.01; RR = 5.40; p = 0.003), and significantly decreased peripheral blood malondialdehyde (MDA) levels (SMD = −7.58; p = 0.001). …”

Table 1_Proton therapy achieves high-dose tumor control with organ preservation in complex metastatic adenoid cystic carcinoma: a case report of a refractory patient with 16 pulmon... by Zejun Lu (2279458)

“…<p>Adenoid Cystic Carcinoma (ACC) is characterized by its aggressive nature, high propensity for perineural invasion, and significant risk of distant metastasis, particularly to the lungs. …”

Figure 7 from Activation of Cell-Intrinsic Signaling in CAR-T Cells via a Chimeric IL7R Domain by Stamatia C. Vorri (19563842)

“…<p>Single-chain proximal IL7Rα CAR-T cells have decreased <i>in vivo</i> antileukemia activity. <b>A,</b> Schematic of the xenograft model. …”

Table 1_Serum neurotransmitter analysis of motor and non-motor symptoms in Parkinson’s patients.docx by Yichun Fan (14295492)

“…Analysis of neurotransmitter metabolism revealed significant changes in the tryptophan (Trp) metabolic pathway in PD patients. …”

Image 2_The effects of antioxidant supplementation on pain, oxidative stress markers, and clinical pregnancy rate in women with endometriosis: a systematic review and meta-analysis... by Yuchan Zhong (22518395)

“…The results showed that antioxidant supplementation significantly alleviated pelvic pain (continuous outcomes: SMD = −2.68; p < 0.00001; binary outcomes: RR = 9.31; p < 0.0001), dysmenorrhea (SMD = −1.77; p = 0.01; RR = 2.39; p = 0.03), and dyspareunia (SMD = −2.33; p = 0.01; RR = 5.40; p = 0.003), and significantly decreased peripheral blood malondialdehyde (MDA) levels (SMD = −7.58; p = 0.001). …”

Data Sheet 1_# Language processing characteristics in normal pressure hydrocephalus: insights from eye-tracking analysis of incorrect responses.docx by Ji-Yeong Kim (3390539)

“…Introduction<p>In patients with Normal Pressure Hydrocephalus (NPH), the aging process results in decreased efficiency of cerebrospinal fluid circulation, leading to ventricular enlargement. …”

Association between Lyn tyrosine kinase and renal injury in patients with systemic lupus erythematosus by Jian Sun (27858)

“…ROC curve analysis suggested Lyn as a reliable predictor for SLE, LN, and lupus activity, with histopathological examination revealing that decreased Lyn expression correlated negatively with the renal pathology index (<i>r</i> = −0.8016, <i>p</i> = 0.0016).…”

Low-speed Rear-end Collisions: Kinematic and Clinical Responses (Video, MRI findings, EMG/NCS results) by Hee Young Lee (22195417)

“…While 58.3% of participants reported immediate post-collision pain, this decreased to 25% within a week, primarily affecting the cervical spine and lower back.…”

Table 2_Dihydromyricetin attenuates age-related macular degeneration: pharmacological effects and exploration of putative targets.docx by Hongyu Zhou (352858)

“…Western blot analysis further confirmed DHM-mediated suppression of apoptosis through regulation of p53, Bax, cleaved caspase-3, and Bcl-2 expression. High-dose DHM significantly attenuated retinal thinning (10.7% reduction), decreased pigment loss, and ameliorated structural disorganization in the outer nuclear layer (ONL). …”

Data Sheet 1_Effects of plant extracts on patients with heart failure: a network meta-analysis of randomized controlled trials.pdf by Jieyin Deng (22563188)

“…Shenfu extract exhibited superior efficacy in decreasing B-type natriuretic peptide (BNP) values (SUCRA: 68.2%) and enhancing the quality of life (QL) (SUCRA: 77.0%). …”

Table 1_Effects and safety of Salvia miltiorrhiza on the improvement of renal function, inflammatory factors, and vascular endothelium in patients with diabetic kidney disease: a m... by Shuyu Zheng (5570231)

“…</p>Conclusion<p>These results indicate that SM preparations could considerably improve renal and vascular endothelial function while simultaneously decreasing harmful inflammatory markers in patients with DKD, which allow it serve as a safe and effective therapeutic option.…”

Table 1_Influence of indigenous non-Saccharomyces yeast strains on the physicochemical and sensory properties of wine fermentation: a promising approach to enhancing wine quality.d... by Sathivel Thivijan (20393742)

“…High-Performance Liquid Chromatography analysis revealed that while tartaric acid levels remained constant, malic acid content decreased, and acetic acid was produced by all strains. …”