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21281
Image 3_NLRP3 deficiency aggravated DNFB-induced chronic itch by enhancing type 2 immunity IL-4/TSLP-TRPA1 axis in mice.tif
Published 2025“…In Nlrp3<sup>-/-</sup> mice, IL-18 expression was downregulated, whereas markers of type 2 immunity, such as IL-4 and thymic stromal lymphopoietin (TSLP), were significantly upregulated in the skin. Furthermore, TRPA1 and its colocalization with the IL-4 receptor were increased in the DRG. …”
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21282
Image 2_NLRP3 deficiency aggravated DNFB-induced chronic itch by enhancing type 2 immunity IL-4/TSLP-TRPA1 axis in mice.tif
Published 2025“…In Nlrp3<sup>-/-</sup> mice, IL-18 expression was downregulated, whereas markers of type 2 immunity, such as IL-4 and thymic stromal lymphopoietin (TSLP), were significantly upregulated in the skin. Furthermore, TRPA1 and its colocalization with the IL-4 receptor were increased in the DRG. …”
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21283
Image 5_NLRP3 deficiency aggravated DNFB-induced chronic itch by enhancing type 2 immunity IL-4/TSLP-TRPA1 axis in mice.tif
Published 2025“…In Nlrp3<sup>-/-</sup> mice, IL-18 expression was downregulated, whereas markers of type 2 immunity, such as IL-4 and thymic stromal lymphopoietin (TSLP), were significantly upregulated in the skin. Furthermore, TRPA1 and its colocalization with the IL-4 receptor were increased in the DRG. …”
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21284
Image 6_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.jpeg
Published 2024“…However, pretreatment with SBP followed by H<sub>2</sub>O<sub>2</sub> inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H<sub>2</sub>O<sub>2</sub>–induced cells. …”
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21285
Image 4_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.jpeg
Published 2024“…However, pretreatment with SBP followed by H<sub>2</sub>O<sub>2</sub> inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H<sub>2</sub>O<sub>2</sub>–induced cells. …”
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21286
Image 3_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.jpeg
Published 2024“…However, pretreatment with SBP followed by H<sub>2</sub>O<sub>2</sub> inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H<sub>2</sub>O<sub>2</sub>–induced cells. …”
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21287
Image 5_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.jpeg
Published 2024“…However, pretreatment with SBP followed by H<sub>2</sub>O<sub>2</sub> inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H<sub>2</sub>O<sub>2</sub>–induced cells. …”
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21288
Image 2_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.jpeg
Published 2024“…However, pretreatment with SBP followed by H<sub>2</sub>O<sub>2</sub> inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H<sub>2</sub>O<sub>2</sub>–induced cells. …”
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21289
Table 1_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.docx
Published 2024“…However, pretreatment with SBP followed by H<sub>2</sub>O<sub>2</sub> inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H<sub>2</sub>O<sub>2</sub>–induced cells. …”
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21290
Image 1_Protective effects of soybean peptides on H2O2-induced oxidative injury in IPEC-J2 cells.jpeg
Published 2024“…However, pretreatment with SBP followed by H<sub>2</sub>O<sub>2</sub> inducement significantly increased cell viability to 72.99%, decreased cell apoptosis, increased SOD, CAT and GSH-Px activity (p < 0.05), down-regulated Bax and Caspase-3 gene expressions (p < 0.05), and up-regulated the gene expressions of ZO-1, Claudin-1, Occludin, catalase, glutathione GPX1, SOD1, HO-1, NQO1 and Nrf2, compared with the single H<sub>2</sub>O<sub>2</sub>–induced cells. …”
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21291
Supplementary file 1_Integrated transcriptomic analysis of COVID-19 stages and recovery: insights into key gene signatures, immune features, and diagnostic biomarkers through machi...
Published 2025“…., B cells and T cells) decreased, while innate immune cells (e.g., monocytes and neutrophils) increased, particularly in ICU patients. …”
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21292
Table 1_Integrated transcriptomic analysis of COVID-19 stages and recovery: insights into key gene signatures, immune features, and diagnostic biomarkers through machine learning.x...
Published 2025“…., B cells and T cells) decreased, while innate immune cells (e.g., monocytes and neutrophils) increased, particularly in ICU patients. …”
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21293
Table 1_Human beta defensin-2 protects the epithelial barrier during methicillin-resistant Staphylococcus aureus infection in chronic rhinosinusitis with nasal polyps.docx
Published 2025“…The presence of hBD-2 significantly reduced the invasive ability of MRSA in HNECs. …”
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21294
Image 3_Human beta defensin-2 protects the epithelial barrier during methicillin-resistant Staphylococcus aureus infection in chronic rhinosinusitis with nasal polyps.tif
Published 2025“…The presence of hBD-2 significantly reduced the invasive ability of MRSA in HNECs. …”
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21295
Image 1_Human beta defensin-2 protects the epithelial barrier during methicillin-resistant Staphylococcus aureus infection in chronic rhinosinusitis with nasal polyps.tif
Published 2025“…The presence of hBD-2 significantly reduced the invasive ability of MRSA in HNECs. …”
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21296
Image 2_Human beta defensin-2 protects the epithelial barrier during methicillin-resistant Staphylococcus aureus infection in chronic rhinosinusitis with nasal polyps.tif
Published 2025“…The presence of hBD-2 significantly reduced the invasive ability of MRSA in HNECs. …”
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21297
Data_Sheet_1_Long-term sheep grazing reduces fungal necromass carbon contribution to soil organic carbon in the desert steppe.pdf
Published 2024“…Our findings indicate that MNC decreased under moderate and heavy grazing, while light grazing did not significantly differ from no grazing. …”
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21298
<b>Concurrent initiation of treadmill exercise protects against angiotensin II-induced renal injury by modulating oxidative stress and autophagy in mice</b>
Published 2025“…The 4-week AngII group exhibited significantly increased fibrosis (~2-fold vs. Veh, p < 0.01), elevated TGF-β and iNOS expression, and disrupted autophagic flux, including increased LC3-II/I ratio and ATG expression, alongside decreased p62 levels. …”
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21299
Data Sheet 1_Elevated SerpinB2 regulates MUC5AC expression via STAT6 signaling in nasal epithelial cells in allergic rhinitis.docx
Published 2025“…</p>Results<p>SerpinB2 expression was significantly increased in both intermittent and persistent AR compared to normal mucosa from HC. …”
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21300
Data Sheet 1_Soil microbiome dysbiosis and rhizosphere metabolic dysfunction drive continuous cropping obstacles of Codonopsis tangshen.docx
Published 2025“…However, their abundance decreased significantly under continuous cropping, ultimately disrupting soil carbon cycling. …”