Video 7_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

“…Multi-omics analysis revealed that TPC2 KO disrupted amino acid metabolism, glycolysis, and protein translation, resulting in reduced ERK1/2 expression and impaired MAPK signalling. These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”

RNA quality photo by zahra seifi (20804762)

“…Moreover, although the expression of the GRP78 gene increased in the sinus tissue of diabetic patients with mucormycosis, it significantly decreased in the same patients after treatment. …”

Image 2_Effects of phospholipase C inhibition on the regulation of membrane lipid metabolism in maize leaves.jpeg by Yulei Wei (4840461)

“…Under NS treatment, MGDG decreased significantly, while DGDG increased.</p>Discussion<p>Our results indicate that NS treatment may cause damage to photosynthetic membrane lipids, whereas the increase in bilayer lipid DGDG may provide a kind of protection to maintain the stability of chloroplasts. …”

Supplementary file 2_Efficacy and safety of the commercial Chinese polyherbal preparation Liu Shen Wan as an adjunctive treatment for herpes zoster and postherpetic neuralgia: a sy... by Yajing Li (1394572)

“…</p>Results<p>A total of 21 RCTs (n = 1,478) were included. Meta-analysis demonstrated that LSW plus conventional treatment significantly outperformed conventional treatment alone in shortening vesicle cessation time [MD = −1.44, 95% CI (−1.66, −0.93), p < 0.00001, I² = 70%], accelerating scab formation (MD = −1.72, 95% CI (−2.09, −1.35), p < 0.00001, I² = 38%), reducing scab shedding time (MD = −2.22, 95% CI (−3.64, −0.80), p = 0.002, I² = 36%), decreasing time to pain resolution (MD = −2.46, 95% CI (−3.52, −1.39), p < 0.00001, I² = 0%), and shortening pain persistence duration (MD = −1.97, 95% CI (−2.49, −1.46), p < 0.00001, I² = 86%). …”

Neural lamella remodeling is needed for macrophage invasion. by Bente Winkler (20760273)

“…(<b>C</b>) Panglial expression of <i>Pvf2</i> and concomitant knockdown of <i>STAT92E</i> decreases the number of invaded macrophages by ~ 10-fold. …”

Figure 4 from Impact of Glucocorticoids on Immune Checkpoint Inhibitor Efficacy and Circulating Biomarkers in Non–Small Cell Lung Cancer Patients by Lauren Polyakov (21672045)

“…Ab, antibody; dex, dexamethasone; i.p., intraperitoneal; NS, not significant; αPD-L1, anti–PD-L1.…”

Image 3_Efficacy and safety of Jianpi Qinghua granules for non-erosive reflux disease with spleen deficiency and damp-heat syndrome: a multicenter, randomized, double-blind, placeb... by Tai Zhang (1398820)

“…Total TCM syndrome scores significantly decreased in both groups, with the JQ group showing greater improvement trends. …”

Image 4_Efficacy and safety of Jianpi Qinghua granules for non-erosive reflux disease with spleen deficiency and damp-heat syndrome: a multicenter, randomized, double-blind, placeb... by Tai Zhang (1398820)

“…Total TCM syndrome scores significantly decreased in both groups, with the JQ group showing greater improvement trends. …”

Image 2_Efficacy and safety of Jianpi Qinghua granules for non-erosive reflux disease with spleen deficiency and damp-heat syndrome: a multicenter, randomized, double-blind, placeb... by Tai Zhang (1398820)

“…Total TCM syndrome scores significantly decreased in both groups, with the JQ group showing greater improvement trends. …”

Relations between action changes post-exposure and pre-exposure behaviors and motives for participants of Experiment 4. by Claire Lugrin (21156528)

“…In the lenient judgment environment, the stricter participants were in their baseline judgment (the further off from the lenient normative environment), the more their prosocial action decreased. Participants who had a perception of the prescriptive norm far from the one displayed during the exposure phase changed their behavior the most. …”

Trivalent chromium ion removal from synthetic wastewater using graphene oxide nanocollector by various flotation mechanisms by Mohammad Sadatipour (20575527)

“…<p>The scarcity of freshwater resources for industrial applications poses a significant global concern. Therefore, wastewater treatment is vital for industrial reuse and decreases environmental damage. …”

Shikonin promotes ferroptosis though NSUN2-mediated m⁵C methylation modification of TFRC in acute myelocytic leukemia by Shuyu Chen (4579207)

“…Overexpression of NSUN2 similarly decreased cell viability and increased cell death and ferroptosis, effects that were mitigated upon silencing of TFRC. …”

Raw data_(Submission ID 247694791) by Shengan Zhu (18242155)

“…Deletion of <i>BbNoxB</i> or <i>BbNoxR</i> decreased fungal virulence compared to the WT strain in topical inoculation experiments. …”

Defective autophagy in vascular smooth muscle cells promote uremic accelerated atherosclerosis by Jianan Feng (11178007)

“…The result showed that the autophagy level and the phosphorylation levels of PI3K and PKB were decreased in the UAAS group. <i>In vitro</i>, uremic serum induced vascular smooth muscle cells (VSMCs) autophagy dysfunction and reduced phosphorylation of PI3K and PKB. …”

Image 6_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg by Xiao Chen (260187)

“…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …”

Image 7_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg by Xiao Chen (260187)

“…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …”

Image 10_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg by Xiao Chen (260187)

“…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …”

Image 8_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg by Xiao Chen (260187)

“…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …”

Image 3_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg by Xiao Chen (260187)

“…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …”

Image 2_SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis.jpeg by Xiao Chen (260187)

“…The sarZ psmβ double mutant was further generated and displayed a significantly decreased hemolytic activity compared with the sarZ mutant. …”