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significantly increased » significant increase (Expand Search)
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19041
Image 1_Elevated miR-17-5p facilitates mycobacterial immune evasion by targeting MAP3K2 in macrophages.jpeg
Published 2025“…Introduction<p>Tuberculosis (TB) rema\ins a major global health challenge. Mycobacterium avium (M. avium), a non-tuberculosis mycobacterium, causes pulmonary infections and can evade host immune surveillance by persisting within macrophages. …”
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19042
Data Sheet 2_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.pdf
Published 2025“…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …”
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19043
Data Sheet 1_miR-223 alleviates DSS-induced colitis by prompting macrophage M2 polarization through PPAR-γ/FOXO1 signaling.pdf
Published 2025“…</p>Results<p>Histopathological analysis showed that miR-223 agomir significantly attenuated DSS-induced colon damage. Proinflammatory cytokines (TNF-α, IL-1β, IL-6) increased in DSS mice, while anti-inflammatory IL-10 decreased—trends reversed by miR-223 supplementation at mRNA/protein levels. …”
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19044
Image 1_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.tiff
Published 2025“…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …”
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19045
Variance of the first 20 principal components from the essential dynamics analysis of the unbiased MD simulation of GumK in the membrane-bound state.
Published 2025“…The cumulative variance shows that the first few principal components account for a significant percentage of the total variance.…”
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19046
Differences between patients and controls.
Published 2024“…Both averaged matrices reveal a plausible pattern wherein positive items (cheerfulness and contentedness) increase each other while decreasing negative items (anxiety and sadness), and vice versa. …”
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19047
The association of piR-651 and piR-823 on metastatic and invasive characteristics of triple negative breast cancer cells
Published 2024“…The expressions of Ki-67, HIF-1α, MMP-2, and MMP-9 genes were measured at 48 h, when both cell lines exhibited the most significant effects of inhibition. The optimal time for proliferation of anti-piR-651 and anti-piR-823 transfected MDA-MB-231 cells was determined to be at 48 h, as indicated by decreased motility and invasion assay results (<i>p</i> < 0.001). …”
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19048
Supplementary file 1_Mechanical properties of 3D voxel-printed materials for cardiovascular tissue imitation.docx
Published 2025“…In the second step, varying the orientation of the structures had a significant influence on the elastic modulus, which was measured. …”
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19049
Table 1_The association between dietary creatine intake and cancer in U.S. adults: insights from NHANES 2007–2018.docx
Published 2025“…For each standard deviation (SD) increase in dietary creatine intake, cancer risk decreased by 5% (adjusted odds ratio (OR) = 0.95, 95% CI: 0.91–0.99, p = 0.025). …”
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19050
Table1_Gut microbiota and metabolomics unveil the mechanisms of Lomatogonium rotatum in ameliorating visceral fat and serum lipids in high-fat diet-induced obese mice.XLSX
Published 2024“…In addition, 16S rRNA sequencing results indicated that the LR intervention remodeled microbial diversity and composition, increased the relative abundance of gut microbes Bacteroidetes and Porphyromonadaceae in HFD-induced obese mice, and decreased the Deferribacteres, Firmicutes and the Firmicutes/Bacteroidetes ratio. …”
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19051
Data Sheet 1_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.pdf
Published 2025“…Monocytes of adjuvant-induced arthritis rats and RA patients expressed less IGFBP5 than normal controls, but its blood levels increased significantly. Adipocytes secreted large amounts of IGFBP5. …”
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19052
Data Sheet 1_Chrysin sensitizes glioblastoma cells and spheroids to temozolomide treatment by reducing EMT and stemness phenotypes, as well as targeting multidrug resistance protei...
Published 2025“…</p>Results<p>The combined treatment was more effective in reducing cell proliferation than either agent alone, in a dose- and time-dependent manner. CHR increased TMZ cytotoxicity by promoting mitochondrial dysfunction, ER stress, autophagy, and apoptosis, and further decreased motility, clonogenicity, EMT status, and stem-like traits. …”
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19053
Table 5_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.docx
Published 2025“…Monocytes of adjuvant-induced arthritis rats and RA patients expressed less IGFBP5 than normal controls, but its blood levels increased significantly. Adipocytes secreted large amounts of IGFBP5. …”
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19054
Table 3_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.xlsx
Published 2025“…Monocytes of adjuvant-induced arthritis rats and RA patients expressed less IGFBP5 than normal controls, but its blood levels increased significantly. Adipocytes secreted large amounts of IGFBP5. …”
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19055
Data Sheet 1_Effects of low-temperature stress during rice heading stage on carbon and nitrogen allocation in paddy eco-system of northeastern China.docx
Published 2025“…</p>Results and Discussion<p>Low-temperature stress significantly reduced rice grain yield of JN809 (sensitive to low-temperature stress) and J88 (tolerant to low-temperature stress) varieties by 27.6% and 21.4%, respectively, This stress tendency increased C and N accumulation in rice stems and leaves, while concurrently decreasing C and N accumulation in panicles. …”
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19056
Table 1_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.docx
Published 2025“…Monocytes of adjuvant-induced arthritis rats and RA patients expressed less IGFBP5 than normal controls, but its blood levels increased significantly. Adipocytes secreted large amounts of IGFBP5. …”
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19057
Table 2_Interaction with IGF1 overrides ANXA2-mediated anti-inflammatory functions of IGFBP5 in vivo.xlsx
Published 2025“…Monocytes of adjuvant-induced arthritis rats and RA patients expressed less IGFBP5 than normal controls, but its blood levels increased significantly. Adipocytes secreted large amounts of IGFBP5. …”
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19058
Data Sheet 1_Effect of surface roughness on the microbiologically influenced corrosion (MIC) of copper 101.docx
Published 2024“…However, a statistically significant reduction in the corrosion rate was recorded when the surface roughness was decreased from ∼2.71 μm to ∼0.006 μm.…”
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19059
Table 4_Distribution and environmental drivers of macrofaunal nematode communities across gradients of methane seepage at cold seeps on Hikurangi Margin (New Zealand) and potential...
Published 2025“…However, a consistent spatial pattern in nematode abundance was observed within all the seep areas on the Hikurangi Margin: abundance was highest at or near the seep centre, decreased steeply away from the centre and was low in the periphery. …”
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19060
Table 6_Global burden of amputation among children and adolescents from 1990 to 2021: systematic analysis of the Global Burden of Disease study 2021.xlsx
Published 2025“…Introduction<p>Amputation among children and adolescents, with its substantial physical, psychological, and economic impacts, remains a significant global health issue.</p>Objectives<p>This study uses data from the Global Burden of Disease (GBD) to examine trends in amputation burden among youth aged 0–19 from 1990 to 2021.…”