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19021
Table 4_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx
Published 2025“…The primary outcomes included relapse rates, Expanded Disability Status Scale (EDSS) scores, and survival outcomes.</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”
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19022
Table 3_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx
Published 2025“…The primary outcomes included relapse rates, Expanded Disability Status Scale (EDSS) scores, and survival outcomes.</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”
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19023
<b>Identification and Validation of LOXL2 as a Prognostic Biomarker and Therapeutic Target in Lung Adenocarcinoma through Multi-Omics and Functional Analysis</b>
Published 2025“…LOXL2 knockdown led to decreased tumor cell proliferation, enhanced apoptosis, and cell cycle arrest. …”
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19024
Thermodynamic properties of non-azeotropic refrigerant heat pumps under full operating conditions with non-phase-change heat sinks and heat soucres
Published 2025“…A comprehensive thermodynamic assessment = across all operating conditions indicated that <i>COP</i> of all configurations decreases markedly as heat production diminishes below 50% of full load. …”
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19025
Supplementary Material for: High serum phosphate promotes cognitive impairment in uremia rats via mediating vascular calcification
Published 2025“…Results: The results showed that both the learning and memory abilities and the spatial exploration ability of the rats in Uremia + Pi group were significantly decreased with enhanced expressions of ALP and Runx2, calcium content and ALP activity, however, STP supplementation significantly alleviated the spatial learning and memory damage, reduced the ALP and Runx2 expressions, calcium content and ALP activity. …”
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19026
Table 2_Association of inflammatory biomarkers with new functional morbidity at hospital discharge in children who survive severe sepsis.docx
Published 2025“…</p>Results<p>New functional morbidity occurred in 38 children (32%) and was associated with increased plasma levels of interleukin (IL)-6, IL-18, sIL-2Ra, MCP1, IL-8 (CXCL8), sIL-1RII, IL-10, MIP1a, and IL-2r and decreased RANTES (CCL5) (p < .001) at all three timepoints. …”
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19027
Data - developmental timing.
Published 2025“…In this study, we examined the function of Trus during <i>Drosophila</i> development. CRISPR/Cas9 generated null mutations in <i>trus</i> lead to partial embryonic lethality, significant larval developmental delay, and complete pre-pupal lethality. …”
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19028
<b>White</b><b>-shouldered starlings </b><b>prefer</b><b> nest boxes with smaller entrance to </b><b>avoid</b><b> nest usurpation</b>
Published 2025“…However, due to large areas of land being utilized for aquaculture and livestock farming, the availability of natural tree cavities in the area has significantly decreased. This scarcity of natural nest sites provided ideal experimental conditions for attracting birds using artificial nest boxes (see Liu et al., 2023). …”
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19029
Supporting data for <b>Drivers, Composition and Potential for Innovative Vector Control Approaches in the mosquito</b>
Published 2025“…</p><p dir="ltr">Brief project description</p><p dir="ltr">Mosquito-borne diseases kill more humans than humans do and have done so for a long time. The most significant diseases transmitted by mosquitoes currently lack effective vaccines, and existing control methods face increasing resistance. …”
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19030
Experiences communicating in noise with aphasia (Harmon et al., 2024)
Published 2024“…“Competing noises”: How background noise impacts the communication experiences of people with mild-to-moderate aphasia. <i>American Journal of Speech-Language Pathology</i>, <i>33</i>(6S), 3393–3409. …”
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19031
Sex-specific brain volume changes in ECM.
Published 2025“…The color code used in the brain views inserted in the graphs indicates whether the brain structure represented is increasing (green), decreasing (red) or remaining unchanged (blue). …”
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19032
Supplementary file 3_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx
Published 2025“…Post-intervention outcomes showed significant improvements: 6MWD increased from 510.07 ± 31.96 to 539.27 ± 44.52 m (P < 0.001); forced expiratory volume in 1 s (FEV1)% predicted increased from 76.87 ± 5.63 to 87.61 ± 7.24 (P < 0.001); and C-ACT score increased from 17.60 ± 1.76 to 22.13 ± 1.46 (P < 0.001).…”
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19033
Supplementary file 2_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx
Published 2025“…Post-intervention outcomes showed significant improvements: 6MWD increased from 510.07 ± 31.96 to 539.27 ± 44.52 m (P < 0.001); forced expiratory volume in 1 s (FEV1)% predicted increased from 76.87 ± 5.63 to 87.61 ± 7.24 (P < 0.001); and C-ACT score increased from 17.60 ± 1.76 to 22.13 ± 1.46 (P < 0.001).…”
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19034
Supplementary file 6_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx
Published 2025“…Post-intervention outcomes showed significant improvements: 6MWD increased from 510.07 ± 31.96 to 539.27 ± 44.52 m (P < 0.001); forced expiratory volume in 1 s (FEV1)% predicted increased from 76.87 ± 5.63 to 87.61 ± 7.24 (P < 0.001); and C-ACT score increased from 17.60 ± 1.76 to 22.13 ± 1.46 (P < 0.001).…”
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19035
Supplementary file 5_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx
Published 2025“…Post-intervention outcomes showed significant improvements: 6MWD increased from 510.07 ± 31.96 to 539.27 ± 44.52 m (P < 0.001); forced expiratory volume in 1 s (FEV1)% predicted increased from 76.87 ± 5.63 to 87.61 ± 7.24 (P < 0.001); and C-ACT score increased from 17.60 ± 1.76 to 22.13 ± 1.46 (P < 0.001).…”
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19036
Supplementary file 4_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx
Published 2025“…Post-intervention outcomes showed significant improvements: 6MWD increased from 510.07 ± 31.96 to 539.27 ± 44.52 m (P < 0.001); forced expiratory volume in 1 s (FEV1)% predicted increased from 76.87 ± 5.63 to 87.61 ± 7.24 (P < 0.001); and C-ACT score increased from 17.60 ± 1.76 to 22.13 ± 1.46 (P < 0.001).…”
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19037
Long-term changes in macronutrients, micronutrients, and potentially toxic elements under 33 years of continuous chemical fertilizer and organic matter application
Published 2025“…The content of macronutrient elements (Ca, Mg, P, and K) remained stable with organic matter added treatments, with Ca and P significantly correlating with C and N (<i>p</i> < 0.05). …”
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19038
Data Sheet 2_Prognostic value of lymph node ratio in patients with non-small cell lung cancer: a systematic review and meta-analysis.zip
Published 2025“…</p>Results<p>This meta-analysis included 11 studies. High LNR was significantly associated with decreased overall survival (OS) (multivariable HR=1.76, 95% CI=1.36-2.27; univariable HR=2.26, 95% CI=1.95-2.63) and increased risk of shorter disease-free survival (DFS) (multivariable HR=1.66, 95% CI=1.48-1.88). …”
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19039
Results of parallel mediation effect test.
Published 2025“…</p><p>Results</p><p>The results confirmed that emotional exhaustion and organizational identification are crucial mediators. Three significant indirect pathways were identified: (1) a simple mediation path through emotional exhaustion; (2) a simple mediation path through organizational identification; and (3) a chained mediation path where job insecurity increased emotional exhaustion, which in turn decreased organizational identification, ultimately leading to lower OCB. …”
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19040
Hypothetical relationship diagram.
Published 2025“…</p><p>Results</p><p>The results confirmed that emotional exhaustion and organizational identification are crucial mediators. Three significant indirect pathways were identified: (1) a simple mediation path through emotional exhaustion; (2) a simple mediation path through organizational identification; and (3) a chained mediation path where job insecurity increased emotional exhaustion, which in turn decreased organizational identification, ultimately leading to lower OCB. …”