Information of core targets. by Guobing Wang (288885)

“…The difference between the single drug group and the corresponding low dose group was significant (P<0.001). After Hela cells were cultured for 72 h, the mRNA and protein expressions corresponding to EGFR, TNF-α, VEGFA, PI3K, AKT and MDM2 were decreased in the experimental group compared with the control group as confirmed by RT-PCR and Western blot, and the extent of the decrease was more obvious with the increase of the drug concentration, and under the condition of the same drug dosage, the effect of the Baicalein group was more pronounced than that of the Wogonin group, and the effect was more obvious in the two-drug group compared with the single-drug group (P<0.05).…”

Composition of Scutellaria Barbata. by Guobing Wang (288885)

“…The difference between the single drug group and the corresponding low dose group was significant (P<0.001). After Hela cells were cultured for 72 h, the mRNA and protein expressions corresponding to EGFR, TNF-α, VEGFA, PI3K, AKT and MDM2 were decreased in the experimental group compared with the control group as confirmed by RT-PCR and Western blot, and the extent of the decrease was more obvious with the increase of the drug concentration, and under the condition of the same drug dosage, the effect of the Baicalein group was more pronounced than that of the Wogonin group, and the effect was more obvious in the two-drug group compared with the single-drug group (P<0.05).…”

GO function enrichment analysis. by Guobing Wang (288885)

“…The difference between the single drug group and the corresponding low dose group was significant (P<0.001). After Hela cells were cultured for 72 h, the mRNA and protein expressions corresponding to EGFR, TNF-α, VEGFA, PI3K, AKT and MDM2 were decreased in the experimental group compared with the control group as confirmed by RT-PCR and Western blot, and the extent of the decrease was more obvious with the increase of the drug concentration, and under the condition of the same drug dosage, the effect of the Baicalein group was more pronounced than that of the Wogonin group, and the effect was more obvious in the two-drug group compared with the single-drug group (P<0.05).…”

KEGG functional enrichment analysis. by Guobing Wang (288885)

“…The difference between the single drug group and the corresponding low dose group was significant (P<0.001). After Hela cells were cultured for 72 h, the mRNA and protein expressions corresponding to EGFR, TNF-α, VEGFA, PI3K, AKT and MDM2 were decreased in the experimental group compared with the control group as confirmed by RT-PCR and Western blot, and the extent of the decrease was more obvious with the increase of the drug concentration, and under the condition of the same drug dosage, the effect of the Baicalein group was more pronounced than that of the Wogonin group, and the effect was more obvious in the two-drug group compared with the single-drug group (P<0.05).…”

Land-use change in Quetta from (a) 1992, (b) 2002, (c) 2013 and (d) 2022. by Naveed Ahmed (2433958)

“…It is evident from the results that barren land in Quetta increased in 2022, whereas build-up area significantly decreased, as shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0317342#pone.0317342.g006" target="_blank">Fig 6</a>. …”

Table 1_Remimazolam used for sedation during spinal anesthesia puncture provides faster sedation effect and increase recovery rate compared to midazolam: a randomized controlled tr... by Peipei Sun (416208)

“…Remimazolam was not associated with an increased risk of adverse events.</p>Conclusion<p>Remimazolam demonstrated superior recovery in sedation depth, with a significantly shorter time to regain consciousness (RASS –4 to −1), compared with midazolam in patients undergoing ultrasound-guided spinal anesthesia. …”

Oligonucleotide primers for gene expression. by Cian Reid (17274007)

“…In response to TLR ligands LPS, Pam3CSK4 and R848, protein analysis of supernatant collected from all calves with BRD revealed significantly increased IL-6, but not IL-1β or IL-8, compared to healthy controls. …”

Calf health information. by Cian Reid (17274007)

“…In response to TLR ligands LPS, Pam3CSK4 and R848, protein analysis of supernatant collected from all calves with BRD revealed significantly increased IL-6, but not IL-1β or IL-8, compared to healthy controls. …”

Design, Synthesis, and Biological Evaluation of New PDE4 Inhibitors for the Treatment of Pressure Ulcers by Xudong Qian (13182676)

“…In a rat PU model, <b>G1</b> exhibited the capability to reduce the expression levels of inflammatory markers in skin tissue, diminish the thickness of the epidermal layer, decrease the number of dermal inflammatory cells, and significantly enhance the quantity of fibroblasts, which effectively expedited the wound healing process. …”

Ranking position of feature importance for each cluster in the post-vaccination period. by Jéssica Villar (21453137)

Ranking position of feature importance for each cluster in the pre-vaccination period. by Jéssica Villar (21453137)

Changes in cytokine production over the second week of culture. by Nils Ågren (21474419)

Predicted behavioural expression of young (orange) and old (blue) individuals that do (treatment) or do not (control) receive an immune challenge. by Antoine Bour (20489426)

“…If an immune-challenged individual’s sickness remains stable (i.e. there is no recovery or increased illness) between behavioural tests then we do not expect to find significant within-individual variation within either age category. …”

Modeling method used. by Claire Teillet (18986264)

“…Additionally, the combination of vegetation and urban structures plays a crucial role in determining the presence of <i>Ae. albopictus</i> larvae in public spaces, where small, organized urban objects and large patches of vegetation increase the likelihood of larval presence. …”

Raw data underlying the findings in this study. by Andrew Mvula (20161161)

“…The relative bone density significantly decreased as standard length and condition factor (<i>K</i>) increased in both sexes. …”

SHAP Values per cluster in the pre-vaccination period show each feature’s importance on COVID-19 mortality. by Jéssica Villar (21453137)

SHAP Values per cluster in the post-vaccination period show each feature’s importance on COVID-19 mortality. by Jéssica Villar (21453137)

Demographics by Country and Gender. by Deeviya Francis Xavier (21485043)

“…We focus on two key aspects: job autonomy, the level of control and discretion employees have over their tasks, and creative self-efficacy, the confidence in one’s ability to generate innovative ideas. Our findings revealed a significant increase in job autonomy following AI integration across all participants. …”

Study Data. by Deeviya Francis Xavier (21485043)

“…We focus on two key aspects: job autonomy, the level of control and discretion employees have over their tasks, and creative self-efficacy, the confidence in one’s ability to generate innovative ideas. Our findings revealed a significant increase in job autonomy following AI integration across all participants. …”

Contribution of each risk factor to the spatial distribution of the risk of overweight or obesity in women aged between 15 and 49 years for DHS 2010 (column 1), DHS 2015−16(column... by Angelina Mageni Lutambi (22097223)

“…<p>Contour line indicates areas of significantly increased or decreased prevalence ratios. …”