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significant level » significance level (Expand Search), significance levels (Expand Search), significant gender (Expand Search)
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19521
Data for Will et al. 2025 Resting metabolic rate is repeatable, but does not affect call characteristics, in the gray treefrog <i>Hyla chrysoscelis</i>
Published 2025“…Nevertheless, RMR was significantly repeatable. We found that RMR decreased across the breeding season, which reduced the consistency in RMR measurements of the same individual over time. …”
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19522
Data Sheet 1_The ERF transcription factor TaERF13-2B functions as a negative regulator of drought tolerance in Arabidopsis and wheat.docx
Published 2025“…In wheat, overexpression of TaERF13-2B under drought stress increased malondialdehyde accumulation, decreased chlorophyll and proline levels, and reduced antioxidant enzyme activity. …”
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19523
Analysis of connexin 43 expression in mice inoculated intravenously with EVs (green) or ICs (blue).
Published 2025“…<p>Confocal microscopy revealed decreased connexin 43 synthesis in mice injected with EVs and ICs <b>(A)</b>. …”
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19524
<b>Human Milk Oligosaccharides Mitigate Infant </b><b>Diarrhea</b><b> </b><b>and </b><b>Anxiety</b><b>-like </b><b>Behaviors</b><b> via Gut Microbiota Modulation in an EPEC O127 In...
Published 2025“…Notably, HMOs reshaped the gut microbiota by increasing the relative abundance of short-chain fatty acids (SCFAs)-producing bacteria (e.g., <i>Lacrimispora</i>), thereby elevating fecal SCFAs levels while decreasing <i>Escherichia</i> and other harmful taxa. …”
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19525
Supplementary Material for: Gut microbiome composition and one-year survival outcomes among patients with reduced ejection fraction heart failure
Published 2025“…Decreased levels of Prevotella, F. prausnitzii, Firmicutes, and Bacteroides, as well as a lower Firmicutes/Bacteroidetes (F/B) ratio, were notable in HFrEF patients, with specific taxa correlating with clinical features like ascites and vitamin D levels. …”
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19526
The prognostic value of the neutrophil-percentage-to-albumin ratio for all-cause and cardiovascular mortality in chronic kidney disease stages G3a to G5: insights from NHANES 2003–...
Published 2025“…High levels NPAR exhibited a significantly elevated risk of both all-cause and CVD mortality in the fully adjusted model. …”
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19527
Image 3_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif
Published 2025“…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …”
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19528
Image 2_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif
Published 2025“…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …”
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19529
Data Sheet 1_Pinostilbene inhibits lung epithelial-mesenchymal transition and delays pulmonary fibrosis by modulating the PI3K/Akt pathway.docx
Published 2025“…Mechanistic studies identified the PI3K/Akt pathway as a target of PIN, with Western blot analysis showing decreased phosphorylation levels of PI3K and Akt. These findings suggest that PIN inhibits pulmonary EMT and delays the progression of pulmonary fibrosis by modulating the PI3K/Akt pathway, providing a promising therapeutic avenue for lung diseases associated with EMT.…”
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19530
Image 1_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif
Published 2025“…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …”
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19531
Data Sheet 1_Molecular and clinical insights into HIV-associated and HIV-negative aggressive B-cell lymphomas: prognostic quantitative biomarker analysis and therapeutic implicatio...
Published 2025“…Immunophenotyping revealed a GCB-like phenotype in HALs, characterized by elevated CD10 and BCL6 expression and decreased MUM1 and BCL2 expression. Patients with HALs had significantly shorter survival (median: 32.1 vs. 46.1 months, P < 0.001). …”
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19532
Measurement of interference efficiency of AjNLRC4 or AjCASP-1 by specific siRNA transfection.
Published 2025“…It was found that after the above treatment, the mRNA and protein levels of AjNLRC4 were significantly decreased. Results are representative of at least three independent experiments, and error bars denote the SD of triplicate wells. …”
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19533
Table 1_Network pharmacology and experimental validation to elucidate the pharmacological mechanisms of OATF against kidney stones.xlsx
Published 2025“…In vivo, OATF significantly decreased serum creatinine (SCR), serum calcium (Ca), serum phosphorus (P), and blood urea nitrogen (BUN) levels in CaOx-induced Sprague-Dawley (SD) rats, indicating its protective effects against KS.…”
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19534
Table 1_Regulation of DNA methylation in lesional tissue of children with atopic dermatitis.docx
Published 2025“…</p>Results<p>The mRNA expression levels of DNMT3A genes were significantly increased, while the mRNA expression levels of DNMT3B, TET1, and TET2 genes were statistically significantly reduced in the lesional tissue of patients compared to the control group. …”
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19535
Genetic prediction of the relationship between mitochondrial proteins and diabetic polyneuropathy risk: a Mendelian randomization study
Published 2025“…</p> <p>Elevated COA3 levels (OR = 0.5774, 95% CI: 0.4466–0.7465, <i>p</i> < 0.01) decreased DPN risk, while elevated NFU1 (OR: 1.3992, 95% CI: 1.0935–1.7904, <i>p</i> = 0.0075) and SARS2 (OR: 1.3660, 95% CI: 1.0651–1.7520, <i>p</i> = 0.0140) increased risk.…”
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19536
Table 1_Gut microbiota alterations and systemic inflammation in community-acquired pneumonia: a prospective gut-lung axis study.docx
Published 2025“…The abundance of short-chain fatty acid-producing genera in CAP patients decreased significantly, such as Blautia and Agathobacter. …”
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19537
Table 1_Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early a...
Published 2025“…Introduction<p>Postpartum sleep disturbances in women are common and can significantly affect maternal mental health and breastfeeding. …”
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19538
Point Application Therapy Targeting Feishu, Pishu and Shenshu Attenuates Asthma by Suppressing Autophagy and the AMPK-mTOR Signalling Pathway
Published 2025“…The treatment additionally decreased expression levels of mTOR, LC3, NF-κB and TGF-β1 while increasing AMPK content. …”
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19539
Table 2_Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early a...
Published 2025“…Introduction<p>Postpartum sleep disturbances in women are common and can significantly affect maternal mental health and breastfeeding. …”
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19540
Semaglutide ameliorates diabetes-associated cognitive dysfunction in mouse model of type 2 diabetes
Published 2025“…<p dir="ltr"><b>Background:</b> Type 2 diabetes mellitus (T2DM) is associated with cognitive dysfunction, which significantly impacts the quality of life. Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has shown potential neuroprotective effects. …”