Image 1_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair... حسب Ulrike Gimsa (9730208)

"…Unlike other mouse lines, DU6 mice do not develop diabetes despite significant obesity. We performed a series of behavioral tests on male mice because obesity is often associated with cognitive and emotional impairment. …"

Table 2_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.docx حسب Fuxing Lin (7418234)

"…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"

Table 3_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa... حسب Jiaochen Luan (9704384)

"…Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …"

Table8_Use of non-specific immunoglobulins in Catalonia in three third-level hospitals: a descriptive analysis of a hospital-prescribed medication registry.docx حسب J. Riera-Arnau (20431328)

"…In the sensitivity analysis, the A-level usage rate decreased to one-third and the B-level usage rate increased by 2–3 times. …"

Data Sheet 2_Integrating single-cell RNA-seq and bulk RNA-seq to explore prognostic value and immune landscapes of methionine metabolism-related signature in breast cancer.docx حسب Yanxian Gao (20555714)

"…Subsequent in vitro experiments demonstrated that silencing APOC1 reduced the generation of tumor-associated macrophages (TAMs) with an M2 phenotype while significantly decreasing the proliferation, invasion, and migration of MDA-MB-231 and MDA-MB-468 breast cancer cell lines.…"

Image 1_Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retrospective cohort study.jpeg حسب Khalaf Kridin (7523390)

"…Introduction<p>Chronic, non-communicable inflammatory diseases (CIDs) affect a large portion of the population, imposing a significant morbidity, encompassing a substantial mortality. …"

Data Sheet 1_Case Report: A case of first-line treatment for rare ROS1 fusion mutation lung adenocarcinoma with entrectinib.pdf حسب Yifan Yang (170387)

"…Subsequently, the patient underwent whole-brain radiotherapy. Significant improvements were noted in her headache and insomnia symptoms. …"

Quantitative results on DRPD dataset. حسب Dunlu Lu (19964225)

"…At the same time, the model size was reduced by 9.3%, and the number of model layers was decreased, reducing computational costs and storage requirements. …"

Data Sheet 1_Integrating single-cell RNA-seq and bulk RNA-seq to explore prognostic value and immune landscapes of methionine metabolism-related signature in breast cancer.csv حسب Yanxian Gao (20555714)

"…Subsequent in vitro experiments demonstrated that silencing APOC1 reduced the generation of tumor-associated macrophages (TAMs) with an M2 phenotype while significantly decreasing the proliferation, invasion, and migration of MDA-MB-231 and MDA-MB-468 breast cancer cell lines.…"

Data Sheet 1_Associations between obesity and arterial stiffness assessed by cardio-ankle vascular index in healthy children and adolescents.docx حسب Yuko Horikoshi (12202859)

"…In contrast, CAVI showed no significant correlation with blood pressure or body weight. …"

Data Sheet 1_Reduced hemolytic complement activity in the classical pathway (CH50) is a risk factor for poor clinical outcomes of patients with infections: a retrospective analysis... حسب Hiroyuki Koami (3878434)

"…</p>Results<p>Of 2,726 patients who met the inclusion criteria, logistic regression models demonstrated that decreased CH50 is a significant predictor of 180-day mortality (OR: 0.98-0.99). …"

Image 1_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa... حسب Jiaochen Luan (9704384)

"…Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …"

CLAD_sequence_files حسب Ryan Hunter (21714311)

"…Association with CLAD severity was driven by changes in phosphoethanolamine and phosphocholine lipids that increased and decreased, respectively, and metabolites from the bacterial pathogen <i>Pseudomonas aeruginosa</i>. …"

Data Sheet 1_Divergent trends and regional disparities in PM2.5 and O3 health economic burdens in China, 2013–2023: an integrated assessment with policy implications.zip حسب Ziqi Tang (10904159)

"…With 0 and 15 μg/m³ taken as the reference concentrations, all-cause mortality decreased by 47.41% (233,173 cases) and 65.55% (240,448 cases), respectively. …"

Table 7_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx حسب Fuxing Lin (7418234)

"…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"

Architecture of MAR-YOLOv9. حسب Dunlu Lu (19964225)

"…At the same time, the model size was reduced by 9.3%, and the number of model layers was decreased, reducing computational costs and storage requirements. …"

Image 4_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa... حسب Jiaochen Luan (9704384)

"…Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …"

Data Sheet 1_Post-COVID syndrome patients show reduced anti-Spike antibodies compared to COVID-recovered controls, but enhanced IgG4/IgG1 switch after the third vaccine dose.pdf حسب Nineth Rossi (22355524)

"…Introduction<p>Long COVID and post-COVID syndromes represent a significant global health crisis and a substantial societal challenge. …"

Data Sheet 1_Global, regional, and national burdens of endometriosis from 1990 to 2021: a trend analysis.docx حسب Hailan Yan (18174379)

"…Background<p>Endometriosis is a common, chronic, estrogen-dependent gynecological disorder that significantly affects patients’ quality of life. However, the disease burden and its trends may be undergoing significant changes, and comprehensive data on this issue are currently lacking. …"

Table 1_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx حسب Wenjun Wang (314231)

"…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…"