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significant event » significant level (Expand Search), significant effects (Expand Search), significant amount (Expand Search)
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18921
Data Sheet 9_Assessing the disease burden of lower respiratory infections attributable to particulate matter pollution: trends from 1990 to 2021 and projections for 2022-2050.pdf
Published 2025“…Children under 5 years of age group still accounted for the most PMP-related deaths, with the number decreasing from 851,458 (95% UI: 211,026 to 1,363,810) in 1990 to 201,078 (95% UI:61,817 to 337,232). …”
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18922
Supplementary Material for: Identification of risk factors associated with metabolic dysfunction-associated steatotic liver disease in psoriatic patients
Published 2024“…There was no significant difference between the mean age of both patient groups (50.4 vs 47.3 years, p=0.26). …”
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18923
Data Sheet 2_LncRNA NRIR inhibits osteogenesis by promoting macrophage M1 polarization through RSAD2/NF-κB axis in peri-implantitis.docx
Published 2025“…However, our previous studies revealed significant upregulation of NRIR in peri-implantitis, suggesting its potential role in peri-implantitis. …”
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18924
Table 1_Impact of short-term (24 h) blood pressure variability on 30-days clinical outcomes of acute strokes at two tertiary hospitals in Dar-es-Salaam.docx
Published 2025“…Functional outcomes improved significantly by day 30: the Barthel Index increased, and mRS scores decreased. …”
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18925
Data Sheet 4_Assessing the disease burden of lower respiratory infections attributable to particulate matter pollution: trends from 1990 to 2021 and projections for 2022-2050.pdf
Published 2025“…Children under 5 years of age group still accounted for the most PMP-related deaths, with the number decreasing from 851,458 (95% UI: 211,026 to 1,363,810) in 1990 to 201,078 (95% UI:61,817 to 337,232). …”
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18926
Data Sheet 1_Unveiling causal immune cell–gene associations in multiple myeloma: insights from systematic reviews and Mendelian randomization analyses.docx
Published 2025“…NCAM1 also exhibited a significant methylation-level association with disease.…”
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18927
Data Sheet 1_MIKC-type MADS-box transcription factor OsMADS31 positively regulates salinity tolerance in rice.pdf
Published 2025“…Conversely, compared with WT plants, 3,3’-diaminobenzidine (DAB) and nitroblue tetrazolium (NBT) staining intensities as well as malondialdehyde (MDA) content were significantly higher in osmads31 mutants and significantly lower in OE lines. …”
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18928
Summertime bedroom overheating in un-airconditioned UK urban apartments: factors influencing subjective and objective sleep outcomes
Published 2025“…</p><p dir="ltr">Results: Night-time (22.00-07.00) bedroom temperatures rose significantly during HN (range BL = 17.5-26.4°C; HN = 22.0-29.3°C, p<0.001) with thermal comfort (p<0.001), ‘restfulness’ (p<0.001) and TST (p<0.05) significantly decreasing, while heat-related sleep disturbance significantly increased (p<0.001). …”
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18929
Image 1_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.tiff
Published 2025“…Healthy control also showed globally increased [<sup>18</sup>F]SMBT-1 uptake. There was no significant correlation between the degree of [<sup>18</sup>F]FDOPA uptake and [<sup>18</sup>F]SMBT-1 uptake in any brain region.…”
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18930
Internal states adjust the Brp compartmental heterogeneity through octopamine.
Published 2025“…*<i>P</i> < 0.05 and ns = not significant. The data underlying this Figure can be found in S1 Data.…”
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18931
Data Sheet 1_Clinical pharmacist interventions in medication review for medication optimization in older hospitalized adults with mental disorders and somatic comorbidities: eviden...
Published 2025“…The number of PIMs also significantly decreased (p < 0.001), with reductions of 29.5% (from 308 to 217) based on the Priscus List and 17.5% (from 343 to 283) according to the Beers Criteria. …”
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18932
30-year trends in incidence of acute STEMI and NSTEMI in the Belgian Province of Luxembourg. A long-term follow-up of the MONICA-BELLUX registry
Published 2025“…The overall AMI incidence decreased by 5.3 events per 100,000 inhabitants annually, from 314 per 100,000 in 1986 to 116 per 100,000 in 2014. …”
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18933
<b>Soil C mineralization and C-Fe coupling: a trade-off between Fenton reaction and </b><b>microbial activity</b><b> under straw mulching in banana orchards</b>
Published 2025“…Although straw mulching negatively impacted soil C mineralization via reducing ROS, it also promoted soil C mineralization through enhancing microbial activity and decreasing Fe-OC, resulting in significantly increased soil C mineralization. …”
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18934
Evolutionarily conserved and functionally important amino acids in Artemis.
Published 2025“…<i>P</i> values were analyzed with Student <i>t</i> test. ns, not significant.</p>…”
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18935
Additional file 2 of Single-cell profiling reveals periosteal signatures of impaired periosteal cells proliferation in a drill-hole model of type 2 diabetes
Published 2025“…Osteoblasts were treated with vehicle or varying concentrations of FGL2 (50, 200 ng/mL) under normal (vehicle) and high glucose (4.5 mg/mL) conditions, and relative cell proliferation was assessed after 48 h to compare the effects under these different conditions. Statistical significance was assessed using one-way ANOVA with Sidak’s multiple comparison test. …”
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18936
Figure 5 from Functional Profiling of p53 and RB Cell Cycle Regulatory Proficiency Suggests Mechanism-Driven Molecular Stratification in Endometrial Carcinoma
Published 2025“…<p>Aurora kinase B inhibitor sensitive endometrial carcinoma cells show more rapidly decreasing percentages of mitotic cells than resistant models in the setting of nocodazole-induced microtubule instability. …”
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18937
FLEXI interactions with RNA-binding proteins.
Published 2024“…RNA-binding sites: I, within introns corresponding to FLEXIs; SS-I and SS-E, bimodally enriched across the 5’- and 3’ splice sites in unspliced pre-mRNAs with the midpoints in the intron or flanking exon (SS-I and SS-E, respectively; Figs <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.g004" target="_blank">4A</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s011" target="_blank">S11</a>). mRNA levels, RBPs whose knockdown resulted in significant difference in mRNA levels (increased or decreased, DESeq2 |LFC|≥1, adjusted p≤0.05) from host gene of FLEXIs with a binding site for that RBP compared to those genes whose transcripts lacked a binding site for the same RBPs based on ENCODE RBP-knockdown datasets (p≤0.05 calculated by Fisher’s exact test; <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s013" target="_blank">S13 Fig</a>). …”
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18938
Ybx1 regulation of its target mRNAs is m<sup>5</sup>C-depdendent (Related to Fig 5).
Published 2025“…<p><b>(A)</b> RT-qPCR confirmed the decreased expression levels of Ybx1 target mRNAs in neural stem cells with Ybx1 knockdown using siRNA. …”
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18939
Supplementary Material for: Camrelizumab combined with Lenvatinib and RALOX-HAIC for unresectable hepatocellular carcinoma (Cal Era): a prospective, single-arm, phase II trial
Published 2025“…Grade 3-4 treatment-related adverse events occurred in 79.5% of the subjects, with the most common being decreased neutrophil count (41%), decreased platelet count (30.8%), and increased aspartate aminotransferase (23.1%). …”
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18940
Table 2_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.docx
Published 2025“…In the comparison between the endoscopic management (EM) and RNU groups, EM was associated with worse overall survival outcomes (HR,1.40; 95%CI,1.08-1.82; P=0.01) based on multivariable Cox regression analysis, and the upper tract recurrence rate (OR,39.06; 95%CI, 14.55-104.85; P<0.00001) was significantly higher in the EM group. On the other hand, in patients treated with KSS, postoperative renal function as measured by eGFR increased by 0.4ml/min/1.73 m<sup>2</sup>, while it decreased by 11.4ml/min/1.73 m<sup>2</sup> in the RNU group (WMD, 11.81 ml/min/1.73 m<sup>2</sup>; 95%CI,9.06-14.56; P<0.0001).…”