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18721
Scarless excision of an insertion sequence in the OmpK36 promoter restores meropenem susceptibility in a non-carbapenemase-producing <i>Klebsiella pneumoniae</i>
Published 2025“…<p>Carbapenem-resistant <i>Klebsiella pneumoniae</i> (CRKP) poses a significant global health challenge due to its limited treatment options and high mortality rates. …”
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18722
Table 1_Predicting ventilator-associated lower respiratory tract infection outcomes using sequencing-based early microbiological response: a proof-of-concept prospective study.doc
Published 2025“…The RQR was calculated as the quantification of A. baumannii determined by QtNGS after treatment to pretreatment. RQR significantly increased on day 4 in the non-survival group (median 5.285), and decreased in the survival group (median 0.1864). …”
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18723
Supplementary file 2_Gut microbiome and serum metabolome alterations in osteosarcoma patients.xlsx
Published 2025“…</p>Results<p>The gut microbial diversity decreased in osteosarcoma patients compared to healthy individuals. …”
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18724
Table 1_The impact of environmental and health messaging, pulse prevalence, and filtering tools on pulse-based food choice and nutrient profiles: a randomized online experiment.doc...
Published 2025“…</p>Discussion<p>Combining messaging with filtering resulted in larger relative increases in pulse choices, suggesting that decreasing product search and identification costs may be an important component of interventions. …”
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18725
Raw Data.
Published 2025“…Enrichment and immune infiltration analyses revealed significant differences in mitochondrial structure and function, immune cell disorders, and signaling pathway activation between the high- and low-mitochondrial gene expression UC groups. …”
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18726
Image 1_Genome-wide identification of GDPD gene family in foxtail millet (Setaria italica L.) and functional characterization of SiGDPD14 under low phosphorus stress.png
Published 2025“…Under low phosphorus stress, the expression levels of SiGDPD3 and SiGDPD14 significantly increased, while SiGDPD1, SiGDPD5, SiGDPD6, and SiGDPD11 showed significant decreases.To identify the function of SiGDPD14, an over-expressed transgenic Arabidopsis was generated. …”
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18727
Image 2_The global burden of hypertension and its epidemiological impacts on adolescents and young adults: projections to 2050.jpeg
Published 2025“…</p>Results<p>From 1990 to 2021, the absolute numbers of hypertension-related deaths, Disability-Adjusted Life Years (DALYs), and Years Lived with Disability (YLDs) increased significantly globally. The age-standardized mortality rate and DALY rate decreased to some extent, while the YLDs rate increased slightly. …”
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18728
Table 1_Sex disparities in the risk of intracranial aneurysm rupture: a case–control study.docx
Published 2024“…In the subgroups based on the covariates used in this study, we only identified statistically significant interaction between sex and age. Although ruptured IAs were most common in males and females aged 50–59 and 60–69 years, respectively, risk of IA rupture peaked at ages 30 and 30–50 years in females and males, respectively, and decreased with age in both sexes.…”
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18729
Data Sheet 1_Preoperative geriatric nutritional risk index as a predictor of postoperative delirium in revision arthroplasty: a 10-year retrospective cohort study.docx
Published 2025“…For each 1-unit increase in GNRI, the risk of POD decreased by 4% (OR = 0.96, 95% CI: 0.94–0.99, p = 0.011). …”
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18730
Data Sheet 1_Using a co-created checklist to improve on-farm biosecurity: an observational pilot intervention with pig farmers and livestock field officers in Sumbawanga, Tanzania....
Published 2025“…<p>The Tanzanian pig sector has the capacity to become market-oriented but it is constrained by significant factors like poor husbandry, management practices and disease, like African swine fever (ASF). …”
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18731
Table 4_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.docx
Published 2025“…Fusobacterium, Prevotella 9, Parvimonas, and Holdemanella were significantly enriched in pre-surgical samples and declined after surgery (p < 0.01). …”
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18732
Table 1_Proteomic profiling of peripheral blood mononuclear cells reveals immune dysregulation and metabolic alterations in kidney transplant recipients with COVID-19.docx
Published 2024“…<p>The COVID-19 pandemic has significantly impacted global health, especially in vulnerable populations like kidney transplant recipients (KTRs). …”
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18733
Image 2_Hippocampus-sparing volume-modulated arc therapy in patients with World Health Organization grade II glioma: a feasibility study.jpeg
Published 2025“…Notably, HS VMAT plans markedly decreased doses to the ipsilateral hippocampus and the contralateral hippocampus, demonstrating its efficacy in hippocampal dose reduction.…”
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18734
Table 1_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx
Published 2025“…</p>Results<p>CIBERSORTx demonstrated the highest sensitivity (r > 0.85) for detecting pituitary cell types, although accuracy decreased for TME components. Application to ten GH-secreting PitNETs with known histological contamination and to public datasets consistently revealed residual normal tissue across hormone-secreting subtypes, excluding silent tumors. …”
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18735
Table 1_Evolving landscape of female cancers along with attributable risk factors in China from 1990 to 2021, and projections to 2040.xlsx
Published 2025“…Background<p>Female cancers pose a significant health burden in China, and this study identified and projected epidemiological trends of these cancers.…”
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18736
Table 1_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.docx
Published 2025“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”
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18737
Table 1_Intergenerational education mobility in India: nonlinearity and the Great Gatsby Curve.docx
Published 2024“…</p>Results<p>Our analysis reveals a high degree of intergenerational persistence in education, although this persistence has decreased over time. Employing quantile regressions, we observe significant nonlinearities in the relationship between fathers’ and sons’ educational outcomes across the educational distribution. …”
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18738
Data Sheet 6_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di...
Published 2025“…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”
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18739
DPOAE differences (in dB SPL), delayed observation minus baseline, as a function of the F2 frequency.
Published 2025“…For each participant, graphs on the top row are for the left ear, while graphs on the bottom row are for the right ear. Significant amplitude decreases [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0309513#pone.0309513.ref049" target="_blank">49</a>] are highlighted with a red background. …”
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18740
Table 2_Human umbilical cord mesenchymal stem cells recover chemotherapy-induced premature ovarian failure.xlsx
Published 2025“…</p>Results<p>After hUC-MSCs therapy, the number of follicles recovered significantly and the atretic follicles decreased significantly. …”