بدائل البحث:
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
significant changes » significant challenge (توسيع البحث)
significant gender » significant concern (توسيع البحث), significant burden (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
significant changes » significant challenge (توسيع البحث)
significant gender » significant concern (توسيع البحث), significant burden (توسيع البحث)
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19981
Table 2_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin...
منشور في 2025"…In vitro experiments validated CA9 as a promising therapeutic target, with its knockdown significantly inhibiting OSCC cell proliferation and migration.…"
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19982
Friedman statistic and p-value across iterations.
منشور في 2025"…However, the model’s robustness decreased when the data structure was shuffled, indicating limited generalization to unseen data. …"
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19983
Table 1_Evaluation of mesenchymal stem cells as an in vitro model for inherited retinal diseases.docx
منشور في 2024"…In the preclinical research phase, in vitro models complement in vivo models by reducing animal studies, decreasing costs, and shortening research timelines. …"
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19984
YOLOv8n detection results diagram.
منشور في 2025"…Significantly, deploying YOLOv8n-BWG on drones yielded promising outcomes in smoke detection, offering innovative approaches and insights for effective smoke monitoring practices.…"
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19985
Glutamate dehydrogenase 2 is required for virulence by facilitating fungal growth in the host hemocoel
منشور في 2025"…Loss of <i>MrGDH2</i> function resulted in significantly reduced virulence during both cuticle-passing and cuticle-bypassing infections but did not affect appressorium formation or cuticle penetration. …"
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19986
Image 1_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif
منشور في 2025"…</p>Results<p>3KO-hiPSC-NSC treatment significantly ameliorated VPA-induced ASD-like behaviors. …"
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19987
Dynamic window based median filtering algorithm.
منشور في 2025"…The computational complexity of the improved model decreased dramatically, but the average classification accuracy was only 1.6% lower than that before the improvement. …"
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19988
Image 7_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.tif
منشور في 2025"…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…"
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19989
YOLOv8n-BWG model structure diagram.
منشور في 2025"…Significantly, deploying YOLOv8n-BWG on drones yielded promising outcomes in smoke detection, offering innovative approaches and insights for effective smoke monitoring practices.…"
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19990
Image 2_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif
منشور في 2025"…</p>Results<p>Behavioral tests revealed that low-frequency EA significantly alleviated depressive-like behaviors and cognitive impairment. …"
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19991
Image 1_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.jpeg
منشور في 2025"…</p>Conclusion<p>Our findings elucidate the molecular mechanism that PCP4 downregulation promotes PCa progression via Ca<sup>2+</sup>/CAMKK2/AMPK/AR pathway, highlighting its significance in CRPC development.</p>…"
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19992
Table 2_Clinical features and genetic analysis of acrodermatitis enteropathica in an ethnic minority infant from Western China: a case report and literature review.xlsx
منشور في 2025"…Her serum zinc level significantly decreased (0.19 mg/L). Whole-exome sequencing revealed a homozygous c.197G > T(p. …"
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19993
Navigation error analysis.
منشور في 2025"…Results show that SIDFM reduces navigation errors by 12.09% at low acceleration and 11.43% at high acceleration while also significantly decreasing positioning errors. These improvements enhance the stability, precision, and safety of AGVs in dynamic manufacturing environments. …"
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19994
Image 6_RBM15-mediated metabolic reprogramming boosts immune response in colorectal cancer.jpeg
منشور في 2025"…In vivo, RBM15 depletion significantly delayed tumor progression and enhanced CD8⁺ T cell infiltration and activation in the tumor microenvironment.…"
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19995
Raw data WB.pdf
منشور في 2025"…Moreover, miR-369-3p significantly decreased the release of pro-inflammatory cytokine IL-8. …"
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19996
Image 2_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.tif
منشور في 2024"…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …"
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19997
Base-case results.
منشور في 2024"…Clinical findings have showed that deprescribing service significantly decreased inappropriate PPIs utilization. …"
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19998
Supplementary file 1_IGF-1 secreted by mesenchymal stem cells affects the function of lymphatic endothelial progenitor cells: a potential strategy for the treatment of lymphedema.d...
منشور في 2025"…These results suggest that MSCs significantly promote the proliferation of LEPCs through the activation of the PI3K/Akt/mTOR pathway in LEPCs by secreting IGF-1, and that IGF-1 also inhibits apoptosis and regulates cell metabolism. …"
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19999
Table 1_Multi-omics analysis reveals that low cathepsin S expression aggravates sepsis progression and worse prognosis via inducing monocyte polarization.xlsx
منشور في 2025"…Inflammatory markers (p < 0.05) and migration ability of LPS-activated monocytes were significantly reduced after CTSS agonist. In addition, CTSS agonist decreased the pulmonary tissue monocyte/macrophages infiltration in septic mice.…"
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20000
DataSheet1_Study on the effects of laser shock peening on the microstructure and properties of 17-7PH stainless steel.docx
منشور في 2024"…The microhardness of the specimens shows a decreasing trend with increasing power density. When the power density is 2.79 GW/cm<sup>2</sup>, the microhardness of the specimen significantly increases to 462.94 HV0.5, which is 22.26% higher than that of the non-peened specimen.…"