Table 2_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.xlsx by Zhenyu Zhao (737165)

“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”

Data Sheet 2_Astragalus polysaccharide modulates the gut microbiota and metabolites of patients with major depressive disorder in an in vitro fermentation model: a pilot study.xlsx by Yuwei Mi (18003969)

“…APS fermentation increased the abundance of Bifidobacterium and decreased the abundance of Lachnoclostridium (p < 0.05). …”

Table 2_High humidity environment increases FBG by impairing the intestinal barrier.docx by Yao Wang (102387)

“…Introduction<p>Climate and environmental changes pose significant threats to human metabolic health; however, the specific effects of individual environmental factors on metabolic diseases remain poorly understood. …”

Table 2_Association of hypertensive disorders of pregnancy with offspring cardiometabolic indicators: a systematic review and meta-analysis.docx by Hong Xu (71477)

“…No significant differences were observed in other indicators.…”

<b>Efficacy of strength and conditioning training on dance injury, physical fitness and dance performance in Chinese pre-professional dancers</b> by Matthew Wyon (11437009)

“…Results: The intervention group demonstrated significant increases in physical fitness (p<0.001), but their dance performance data remained statistically unchanged (p>0.05). …”

Table 3_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.xlsx by Zhenyu Zhao (737165)

“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”

Image 3_Mitochondrial metabolism is rapidly re-activated in mature neutrophils to support stimulation-induced response.tif by Jorgo Lika (21189020)

“…Treatment with these inhibitors also impacts neutrophil redox status, migration, and apoptosis without significantly changing overall bioenergetics.</p>Conclusions<p>Together, these results demonstrate that mitochondrial metabolism is dynamically remodeled and plays a significant role in neutrophils. …”

Image 3_The global burden of hypertension and its epidemiological impacts on adolescents and young adults: projections to 2050.jpeg by Chaofeng Niu (17746406)

“…</p>Results<p>From 1990 to 2021, the absolute numbers of hypertension-related deaths, Disability-Adjusted Life Years (DALYs), and Years Lived with Disability (YLDs) increased significantly globally. The age-standardized mortality rate and DALY rate decreased to some extent, while the YLDs rate increased slightly. …”

Table 3_High humidity environment increases FBG by impairing the intestinal barrier.xlsx by Yao Wang (102387)

“…Introduction<p>Climate and environmental changes pose significant threats to human metabolic health; however, the specific effects of individual environmental factors on metabolic diseases remain poorly understood. …”

Table 3_Inequalities and age-period-cohort effects of global and regional burden for interstitial lung disease and pulmonary sarcoidosis: based on Global Burden of Disease study 20... by Lei Zhang (38117)

“…Background<p>Interstitial lung disease (ILD) and pulmonary sarcoidosis pose significant disease burdens on a global scale.</p>Methods<p>The underlying data was derived from the Global Burden of Disease (GBD) 2021 database. …”

Table 6_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv by Zhenyu Zhao (737165)

“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”

Image 3_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Burden o... by Yangtian Jiao (21725018)

“…</p>Conclusion<p>Despite significant global progress, disparities persist, particularly in low- and middle-income regions. …”

Table 3_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx by Mattia Dalle Nogare (22696022)

“…</p>Results<p>CIBERSORTx demonstrated the highest sensitivity (r > 0.85) for detecting pituitary cell types, although accuracy decreased for TME components. Application to ten GH-secreting PitNETs with known histological contamination and to public datasets consistently revealed residual normal tissue across hormone-secreting subtypes, excluding silent tumors. …”

Table 5_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv by Zhenyu Zhao (737165)

“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”

Table 8_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv by Zhenyu Zhao (737165)

“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”

Table 3_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx by Thibaud Dauphin (21196820)

“…Compared to a monolayer reference process, sEV yield decreased two-fold in SpF, but increased two-fold in STBr. …”

Image 5_The global burden of hypertension and its epidemiological impacts on adolescents and young adults: projections to 2050.jpeg by Chaofeng Niu (17746406)

“…</p>Results<p>From 1990 to 2021, the absolute numbers of hypertension-related deaths, Disability-Adjusted Life Years (DALYs), and Years Lived with Disability (YLDs) increased significantly globally. The age-standardized mortality rate and DALY rate decreased to some extent, while the YLDs rate increased slightly. …”

Workflow of the study. by Hongliang Chen (538815)

“…Enrichment and immune infiltration analyses revealed significant differences in mitochondrial structure and function, immune cell disorders, and signaling pathway activation between the high- and low-mitochondrial gene expression UC groups. …”

Supplementary Material for: The effectiveness of regionalization of perinatal care and specific facility-based interventions: A systematic review by Ali A.A. (19754238)

“…Results: Implementation of regionalization programs significantly decreased maternal and perinatal mortality. …”

Minimum data set used in the article. by Shizhen Xu (4474321)

“…<div><p>The dynamics and balance of soil carbon, nitrogen, and phosphorus significantly affect soil microbial activity and plants’ nutrient absorption and utilization. …”