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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant i » significant _ (Expand Search), significant co (Expand Search), significant 17 (Expand Search)
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20381
Image 5_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif
Published 2025“…It reduced hippocampal neuroinflammation (decreased IL-6 and TNF-α) and attenuated microglial overactivation (reduced Iba1+ cells), correcting synaptic pruning abnormalities. …”
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20382
Image 4_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif
Published 2025“…It reduced hippocampal neuroinflammation (decreased IL-6 and TNF-α) and attenuated microglial overactivation (reduced Iba1+ cells), correcting synaptic pruning abnormalities. …”
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20383
Image 2_Immunomodulatory effects of probiotic Lactobacillus brevis ZG2488 on SARS-CoV-2 vaccine responses in mice.tif
Published 2025“…</p>Results<p>ZG2488 intervention significantly enhanced local mucosal humoral immunity in the respiratory tract (increased SARS-CoV-2-specific IgG in BALF) and systemic Th1 cellular immunity (increased IFN-γ secretion by splenocytes). …”
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20384
<b>Collapsin response mediator protein 2 modulates synaptic function by stabilizing the surface expression of phosphorylated AMPA receptor GluA2 subunits</b>
Published 2025“…Upon phorbol myristate acetate (TPA) induced activation of protein kinase C (PKC), the surface expression of GluA2 decreased significantly, as phosphorylation of GluA2 at the S880 site is known to promote its internalization. …”
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20385
Image 6_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif
Published 2025“…It reduced hippocampal neuroinflammation (decreased IL-6 and TNF-α) and attenuated microglial overactivation (reduced Iba1+ cells), correcting synaptic pruning abnormalities. …”
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20386
Image 2_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif
Published 2025“…It reduced hippocampal neuroinflammation (decreased IL-6 and TNF-α) and attenuated microglial overactivation (reduced Iba1+ cells), correcting synaptic pruning abnormalities. …”
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20387
Model inputs.
Published 2024“…Clinical findings have showed that deprescribing service significantly decreased inappropriate PPIs utilization. …”
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20388
Simultaneous Determination of the Bioavailable Fraction of Eight Elements in Soil Using an Automated Extraction Device and Inductively Coupled Plasma - Optical Emission Spectrometr...
Published 2025“…Compared with manual methods, the relative standard deviation (RSD) of element detection has been significantly reduced, with values decreasing from 2.01%–23.5% to 1.54%–9.69%. …”
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20389
Data Sheet 2_Dendritic cells in the human vaginal mucosa can direct CD4+ T cell responses by expressing surface OX40L.pdf
Published 2025“…Neutralizing OX40L with anti-OX40L antibody significantly decreased the frequency of Th2-type CD4<sup>+</sup> T cells with a reduction of CD4<sup>+</sup> T cell proliferation, while increasing the frequency of IL - 10-producing CD4<sup>+</sup> T cell responses. …”
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20390
Image 2_Hyodeoxycholic acid modulates gut microbiota and bile acid metabolism to enhance intestinal barrier function in piglets.tif
Published 2025“…Additionally, HDCA significantly upregulated ileal gene expression of CYP7A1 (cytochrome P450 family 7 subfamily A member 1) and TGR5 (G protein-coupled bile acid receptor 1) in both SPF-HDCA and OPM-HDCA groups compared to their respective controls (p < 0.05). …”
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20391
Image 3_Hyodeoxycholic acid modulates gut microbiota and bile acid metabolism to enhance intestinal barrier function in piglets.tif
Published 2025“…Additionally, HDCA significantly upregulated ileal gene expression of CYP7A1 (cytochrome P450 family 7 subfamily A member 1) and TGR5 (G protein-coupled bile acid receptor 1) in both SPF-HDCA and OPM-HDCA groups compared to their respective controls (p < 0.05). …”
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20392
Flow Chart of the Study Steps.
Published 2025“…</p><p>Results</p><p>The IP-GBL intervention significantly improved students’ self-efficacy in the intervention group compared to the control group (F = 26.51, df = 1.57, p-value = 0.0001, Partial Eta Squared = 0.31). …”
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20393
Supplementary Material for: Seizure Burden Before and After Lidocaine as Add-on Therapy in (a)EEG-Confirmed Neonatal Seizures
Published 2025“…After LDC administration, median TSB decreased significantly from 31 (interquartile range, IQR 16–68) to 0 minutes (IQR 0–0, p<0.01), and MSB from 10 (IQR 6–41) to 0 min/hour (IQR 0–0, p<0.01). …”
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20394
Table 3_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx
Published 2024“…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”
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20395
Table 2_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx
Published 2024“…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”
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20396
Fasting inhibits glycolysis and migration/invasion in gallbladder cancer via PCBP2/ANGPTL4 signaling
Published 2025“…Knockdown and overexpression of PCBP2, combined with in vitro and in vivo assays using fasting mimic medium or diets, were conducted to provide functional significance. The effect of PCBP2 on glycolysis was assessed by glucose uptake, lactate production, oxygen consumption rate, and limiting glycolytic-associated enzymes (PDK1, PKM2, and HK-2). …”
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20397
Supplementary Material for: MicroRNA-4497 is Downregulated in Pediatric Allergic Diseases and Suppresses Th2 Inflammation in an Animal Model
Published 2025“…Furthermore, levels of IL-4, MDC and methacholine Penh were significantly decreased in a miR-4497 treated mouse model. …”
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20398
Table 4_Gut microbiota alterations in golden snub-nosed monkeys during food shortage and parturition-nursing periods.doc
Published 2025“…We found that in adult males, gut microbiota diversity significantly decreased in food shortages and parturition-nursing period. …”
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20399
Table 3_Gut microbiota alterations in golden snub-nosed monkeys during food shortage and parturition-nursing periods.doc
Published 2025“…We found that in adult males, gut microbiota diversity significantly decreased in food shortages and parturition-nursing period. …”
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20400
<b>The taste of rebirth: a dual exploration of Wuhuang pork Flavoromics and metabolomics</b>
Published 2025“…The results showed that the pH value of Wuhuang pork was in the range of 5.57-6.17, while the pH of the longissimus dorsi muscle (LDM) decreased rapidly, while that of the psoas major muscle (PMM) remained stable. …”