Search alternatives:
significant increases » significant increase (Expand Search), significantly increased (Expand Search), significantly decreased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant degs » significant genes (Expand Search), significant adverse (Expand Search), significant cause (Expand Search)
degs decrease » mean decrease (Expand Search), teer decrease (Expand Search), we decrease (Expand Search)
significant increases » significant increase (Expand Search), significantly increased (Expand Search), significantly decreased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant degs » significant genes (Expand Search), significant adverse (Expand Search), significant cause (Expand Search)
degs decrease » mean decrease (Expand Search), teer decrease (Expand Search), we decrease (Expand Search)
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PCV2d Rep disrupts cGAS oligomerization and phase separation.
Published 2025“…(E) Immunoblotting assay for cGAS complexes incubated with cross-linker between recombinant pcGAS full length and increasing doses of PCV2d Rep proteins. …”
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Insufficient disulfide bond formation results in a decrease in alkaline phosphatase activity and accumulation of the reduced form of DegP in LCFA-utilizing cells.
Published 2020“…<i>(E) The reduced form of DegP accumulates significantly in oleate-grown cells</i>. …”
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Peptides derived from US1 bind to cGAS and inhibit its activation.
Published 2025“…In a mixture of 2.5 μM ISD45, peptide AB and cGAS, proteins and peptides were increased in a molar ratio of 1:0 to 1:32, followed by EMSA. …”
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PCV2d Rep inhibits IFN-I production.
Published 2025“…(D) Schematic representation of cGAS-STING signaling pathway. (E, F, G, and H) iPAMs were co-transfected pcGAS and pSTING (E), pcGAS (F), pSTING (G) and pTBK1 (H) plasmids and increasing doses of PCV2d Rep plasmid for 24 h. …”
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The DEG number and clustering analysis of DEG expression profile.
Published 2019“…Each column represents one sample, and each row represents one DEG. Red indicates increased expression, and blue indicates decreased expression.…”
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Alpha-herpesvirus US1 protein inhibits cGAS-mediated IFN-β induction.
Published 2025“…<b>(L)</b> Detection of IFN-β promoter activation in HEK-293T cells was performed 24 hours after transfection with the IFN-β-Luc reporter plasmid, PRV or HSV-1 US1 protein expression plasmids, or an empty vector, with or without co-transfection of cGAS and STING, using the dual-luciferase reporter assay. ns, not significant; ***<i><i>P</i></i> < 0.0001. …”
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