Showing 19,181 - 19,200 results of 21,342 for search '(( ((significant long) OR (significant level)) decrease ) OR ( significant decrease decrease ))', query time: 0.61s Refine Results
  1. 19181

    Table 1_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

    Published 2024
    “…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”
  2. 19182

    Image 1_Exploring the role of LOX family in glioma progression and immune modulation.jpeg by Chen Liu (75209)

    Published 2025
    “…This study aims to investigate the LOX family’s expression, prognostic significance, and immune infiltration dynamics in glioma to identify potential therapeutic targets.…”
  3. 19183

    Table 3_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

    Published 2024
    “…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”
  4. 19184

    Image_4_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.JPEG by Bin Zhang (64682)

    Published 2025
    “…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …”
  5. 19185

    Table_1_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.XLSX by Bin Zhang (64682)

    Published 2025
    “…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …”
  6. 19186

    Table 1_Nitrogen and phosphorus fertilizer use efficiency improves alfalfa (Medicago sativa L.) production and performance in alkaline desert soil.docx by Yanliang Sun (20741819)

    Published 2025
    “…Optimizing the combination of nitrogen and phosphorus fertilizers can maximally significantly enhance farmers’ economic returns while concurrently mitigate soil environmental pollution. …”
  7. 19187

    Table 2_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

    Published 2024
    “…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”
  8. 19188

    Data Sheet 1_A comprehensive examination and analysis of the effectiveness and safety of finerenone for the treatment of diabetic kidney disease: a systematic review and meta-analy... by Jianyu Chen (2624254)

    Published 2024
    “…</p>Results<p>The analysis of 4 randomized controlled trials involving 13,943 participants found that finerenone treatment significantly decreased the urine albumin-to-creatinine ratio compared to placebo. …”
  9. 19189

    Fasting inhibits glycolysis and migration/invasion in gallbladder cancer via PCBP2/ANGPTL4 signaling by Ying Tao (469347)

    Published 2025
    “…We found that fasting could inhibit glycolysis and cell migration/invasion in GBC cells and that fasting mimic diets could significantly inhibit GBC cell proliferation in a mouse xenograft model. …”
  10. 19190

    Table 1_Downregulation of HDGF inhibits tumorigenic phenotypes of hypopharyngeal squamous cell carcinoma by suppressing the AKT/mTOR/VEGF pathway.xlsx by Feilong Yang (1472296)

    Published 2025
    “…Western blotting demonstrated that HDGF knockdown suppressed AKT/mTOR signaling, as indicated by reduced p-AKT and p-mTOR levels, and decreased VEGFA expression.</p>Conclusion<p>Our findings establish HDGF as a key promoter of HSCC progression through dual regulation of EMT and AKT/mTOR/VEGF pathways, suggesting its potential as a therapeutic target. …”
  11. 19191

    Image 1_Construction of a novel cuproptosis-related gene signature for predicting microenvironment, prognosis and therapeutic response in cervical cancer.tif by Yaqi Cui (10798865)

    Published 2025
    “…Moreover, the overexpression of FOXJ1 (one of the DEGs) significantly decreased the proliferation, invasion, migration and Epithelial-Mesenchymal Transition (EMT) process in cervical cancer cells. …”
  12. 19192

    Presentation_1_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.pdf by Bin Zhang (64682)

    Published 2025
    “…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …”
  13. 19193

    Data Sheet 1_Herbal essential oils improve growth, antioxidant response, and gene expression in Nile Tilapia fingerlings.pdf by Malik Khalafalaa (22225135)

    Published 2025
    “…Hematological parameters increased, while serum cholesterol and triglyceride levels decreased. Enhanced lysozyme activity, phagocytic rate, IgM concentration, and antioxidant enzymes (SOD and CAT) were observed in the 30 and 60 mL/kg groups. …”
  14. 19194

    Image 1_Association of inflammatory biomarkers with new functional morbidity at hospital discharge in children who survive severe sepsis.pdf by Mallory A. Perry-Eaddy (20842868)

    Published 2025
    “…</p>Results<p>New functional morbidity occurred in 38 children (32%) and was associated with increased plasma levels of interleukin (IL)-6, IL-18, sIL-2Ra, MCP1, IL-8 (CXCL8), sIL-1RII, IL-10, MIP1a, and IL-2r and decreased RANTES (CCL5) (p < .001) at all three timepoints. …”
  15. 19195

    Experiment 3 –trial E. by Ottavia Benedicenti (9100619)

    Published 2024
    “…Violin plots show Cq median (solid line). Statistical significance levels were calculated with the GraphPad Prism v9.3.1 (* = p ≤ 0.05; n = 3).…”
  16. 19196

    Image 3_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif by Minzhen Deng (11267109)

    Published 2025
    “…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …”
  17. 19197

    Image 2_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif by Minzhen Deng (11267109)

    Published 2025
    “…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …”
  18. 19198

    Data Sheet 1_Pinostilbene inhibits lung epithelial-mesenchymal transition and delays pulmonary fibrosis by modulating the PI3K/Akt pathway.docx by Xin Yu (124814)

    Published 2025
    “…Mechanistic studies identified the PI3K/Akt pathway as a target of PIN, with Western blot analysis showing decreased phosphorylation levels of PI3K and Akt. These findings suggest that PIN inhibits pulmonary EMT and delays the progression of pulmonary fibrosis by modulating the PI3K/Akt pathway, providing a promising therapeutic avenue for lung diseases associated with EMT.…”
  19. 19199

    Image 1_Tetramethylpyrazine attenuates the blood-brain barrier damage against ischemic stroke by targeting endothelin-1/Akt pathway in astrocytes.tif by Minzhen Deng (11267109)

    Published 2025
    “…In the MCAO animal model, TMP improved neurological scores, decreased infarct size, and lowered ET-1 levels, thus strengthening the blood-brain barrier and reducing oxidative stress. …”
  20. 19200

    Supplementary file 3_Efficacy of Xiaoyao-san preparations in treating Hashimoto’s thyroiditis: a meta-analysis and systematic review.docx by Chengna Wang (21535973)

    Published 2025
    “…Meta-analysis demonstrated that XYS preparations significantly reduced TPOAb levels [SMD = −0.74, 95% CI (−1.02, −0.46), p < 0.00001]. …”