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significant part » significant gap (Expand Search), significant portion (Expand Search), significant cause (Expand Search)
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19481
Table1_Biomechanical effects of different mandibular movements and torque compensations during mandibular advancement with clear aligners: a finite element analysis.DOCX
Published 2024“…</p>Results<p>When the mandibular advancement was equal to or slightly excessed the occlusal opening distance, stress on the posterior PDL decreased and became more evenly distributed. Increasing the occlusal opening distance significantly raised stress on the posterior PDL and caused grater labial inclination of the mandibular anterior teeth. …”
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19482
Table 3_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.docx
Published 2025“…</p>Results<p>AB4 ameliorated CLP-induced lung injury in mice, as evidenced by reduced pathological damage, lower injury scores, and a decreased lung wet-to-dry weight ratio. In vivo, AB4 significantly reduced levels of pro-inflammatory cytokines (IL-1β, TNF-α, and IL-6), decreased oxidative stress markers MDA and DHE, and increased GSH levels. …”
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19483
Supplementary Material for: Alpinia galanga essential oil mitigates gentamycin-induced renal injury: in silico and in vivo studies
Published 2025“…Results: Network Pharmacology suggested Toll-like receptors 4 (TLR4), and Interleukin-1beta (IL-1β) as potential targets of Gal EO components in Genta induced renal toxicity. Gal EO significantly decreased Cr, uric acid, BUN, CysC, NGAL and Kim-1 and the urine albumin/creatinine ratio. …”
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19484
Table 1_Effects of compound probiotics on growth performance, immunity, antioxidant capacity and gut microbiota in weaned rabbits.docx
Published 2025“…</p>Results and discussion<p>Our results showed that dietary supplementation with probiotic significantly promoted growth performance (e.g., increased average daily gain and decreased feed-to-gain ratio), enhanced immune function (reflected by elevated plasmic immunoglobulin levels and reduced pro-inflammatory cytokine concentrations) and improved antioxidant capacity (manifested by higher activities of superoxide dismutase and glutathione peroxidase and lower malondialdehyde content) in weaned rabbits. …”
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19485
Age-related driver injury occurrence from crashes at curve–grade combined segments
Published 2024“…</p> <p>The results emphasize the significance of tailored education and outreach countermeasures, particularly for teen and older drivers, aimed at decreasing the likelihood of injuries in such driving environments. …”
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19486
Supplementary Material for: Camrelizumab combined with Lenvatinib and RALOX-HAIC for unresectable hepatocellular carcinoma (Cal Era): a prospective, single-arm, phase II trial
Published 2025“…Grade 3-4 treatment-related adverse events occurred in 79.5% of the subjects, with the most common being decreased neutrophil count (41%), decreased platelet count (30.8%), and increased aspartate aminotransferase (23.1%). …”
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19487
Data Sheet 1_Physical activity of moderate-intensity optimizes myocardial citrate cycle in a murine model of heart failure.pdf
Published 2025“…Interestingly, 8-sWR significantly decreased myocardial citrate content in the presence of unchanged myocardial [BCAAs], ETC proteins content and mtDNA copy number.…”
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19488
Table_1_Receptor Tyrosine Kinase Inhibitor Sunitinib as Novel Immunotherapy to Inhibit Myeloid-Derived Suppressor Cells for Treatment of Endometriosis.xlsx
Published 2025“…We found that Sunitinib significantly decreased the endometriotic lesion size and weight after 1 and 3 weeks, and decreased p-STAT3 activation in MDSCs after 1 week of treatment. …”
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19489
Effect of session on winning model parameters for set size = 2 and set size = 4 for both male and females.
Published 2024“…Use of one-back strategy parameters changed significantly across sessions for male mice with (C) S1 “Inappropriate Lose Shift” decreasing across sessions, <i>p</i> = 0.01 (D) S2 = S4 “Stimulus Insensitive Win Stay” increasing, <i>p</i> = 0.009 and (E) S3 “Inappropriate Lose Stay” decreasing, <i>p</i> < 0.0001. …”
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19490
Long-Term Effects of Adalimumab in Juvenile Idiopathic Arthritis-Associated Uveitis: 3- and 6-Year Results of the ADJUVITE Trial
Published 2025“…The mean dose of methotrexate decreased significantly from 11.3 ± 4.4 mg/week at the end of the trial to 5.2 ± 6.2 mg/week at the last follow-up (<i>p</i> = 0.002). …”
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19491
DataSheet1_Clinical associations of complement-activating collectins, collectin-10, collectin-11 and mannose-binding lectin in preterm neonates.pdf
Published 2024“…An important finding was the decreased concentrations of CL-10, CL-11 and MBL in respiratory distress syndrome (RDS). …”
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19492
Image2_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …”
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19493
DataSheet1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer...
Published 2024“…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …”
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19494
Image1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d...
Published 2024“…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …”
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19495
<b>Nonlinear and Sex-Specific Associations of Vitamin D Metabolites with Inflammatory Blood Markers in 455,000 Adults</b>
Published 2025“…Neutrophil counts were lowest at 25(OH)D levels of ~40–60 nmol/L and increased significantly at both lower and higher extremes (p < 0.001). …”
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19496
<b>Nonlinear and Sex-Specific Associations of Vitamin D Metabolites with Inflammatory Blood Markers in 455,000 Adults</b>Item
Published 2025“…Neutrophil counts were lowest at 25(OH)D levels of ~40–60 nmol/L and increased significantly at both lower and higher extremes (p < 0.001). …”
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19497
HPV18 induces differential host CTCF binding in primary HFKs.
Published 2025“…<p>CTCF-bound peaks were identified by ChIP-Seq analysis in two independent HFK donors. Significantly enriched peaks were identified using MACs (version 1.4.3) with a p-value cut-off of 1 × 10<sup>−5</sup>. …”
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19498
Supplementary file 1_“We find that…” changing patterns of epistemic positioning in research writing.docx
Published 2025“…</p>Results<p>Our findings show that epistemic positioning has significantly decreased across all four disciplines over time, with writers increasingly preferring less use of epistemic markers in pursuit of an objective, data-based, and scientific style.…”
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19499
Supplementary data.xlsx
Published 2025“…However, recent studies have indicated that the telomere length of somatic cells can be drastically decreased in the offspring receiving in vitrofertilization (IVF) therapy, however, the underlying molecular mechanism remains unknown. …”
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19500
TNC promotes bone regeneration via inflammatory macrophage
Published 2024“…Transplantation of macrophages derived from injured periosteum is able to rescue the decreased skeletal stem cells and impaired bone regeneration caused by TNC deficiency. …”