Molecular-docking simulation of the TsSPc–CK8 complex in Caco-2 cells. by Wen Wen Zheng (17721404)

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(A–D) Representative immunoblots for the reporter assays shown in Fig 4A–D. by Lorenza Cutrone (21144285)

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HEK.219 cells were treated with the indicated siRNAs for 24h. by Lorenza Cutrone (21144285)

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CK8 knockdown and ROCK1 inhibitor abolished rTsSPc-reduced TJs expression in Caco-2 monolayers by IFA. by Wen Wen Zheng (17721404)

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PAS staining of intestinal sections from <i>T. spiralis</i>-infected mice pretreated with DAS and Y27632. by Wen Wen Zheng (17721404)

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qPCR and Western blotting of CK8 knockdown blocking the rTsSPc-activated pathway and -reduced TJs expression. by Wen Wen Zheng (17721404)

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IFA, GST pull-down and Co-IP assay of specific binding between rTsSPc and CK8. by Wen Wen Zheng (17721404)

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qPCR and Western blotting of activation of CK8 receptor and RhoA/ROCK1 pathway proteins in Caco-2 cells treated with rTsSPc and IIL ES antigens. by Wen Wen Zheng (17721404)

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CK8 knockdown and ROCK1 inhibitor suppressed rTsSPc-induced disruption of the Caco-2 monolayer and blocked rTsSPc-promoted IIL invasion. by Wen Wen Zheng (17721404)

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Intraperitoneal injection protocol for inhibitors (A), inhibitors DAS and Y27632 reduced intestinal permeability (B) and intestinal adult worm burden (C) of infected mice. by Wen Wen Zheng (17721404)

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HE staining showed that DAS and Y27632 alleviated intestinal inflammation in <i>T. spiralis</i>-infected mice. by Wen Wen Zheng (17721404)

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The ROCK1 pathway inhibitor Y27632 prevented rTsSPc from activating the ROCK1 pathway and reducing TJs expression. by Wen Wen Zheng (17721404)

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qPCR (A-D) and ELISA (E-H) detection of inflammatory cytokines in intestine of <i>T. spiralis</i>-infected mice. by Wen Wen Zheng (17721404)

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RTA408 promotes Nrf2 expression. by Hongmei Qian (538647)

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RTA408 inhibits excessive autophagy in the eyes of glaucomatous mice. by Hongmei Qian (538647)

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RTA408 inhibits the mitophagy pathway. by Hongmei Qian (538647)

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The original plotting data. by Hongmei Qian (538647)

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Comparisons of electrolyte level of <i>H</i>. <i>pylori</i>-infected and non-infected study participants at JMC, 2023 (Mann–Whitney U-Test). by Negussie Sarbecha (20108068)

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Relative abundance at the genus level for <i>Akkermansia</i>, <i>Bacteroides</i>, <i>Bifidobacterium</i>, <i>Clostridium_XlVa</i>, <i>Faecalibacterium</i>, <i>Lactobacillus</i>, <i... by Xueyan Lin (448667)

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Flexural strengths of alkali-activated composites with different SDW levels when cured for 28, 60, and 90 days. by Liang Li (46069)

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