بدائل البحث:
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
significant threat » significant increase (توسيع البحث)
significant effect » significant impact (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
significant threat » significant increase (توسيع البحث)
significant effect » significant impact (توسيع البحث)
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21061
Table 2_Potential marker genes for psoriasis revealed based on single-cell sequencing and Mendelian randomization analysis.xlsx
منشور في 2025"…</p>Results<p>Seven genetically informed candidate genes were identified as being significantly associated with psoriasis susceptibility. …"
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21062
Data Sheet 6_Beyond salt tolerance: SOS1-13’s pivotal role in regulating the immune response to Fusarium oxysporum in Solanum phureja.docx
منشور في 2025"…Conversely, silencing the ortholog gene NbSOS1-13 in Nicotiana benthamiana showed more accumulation of ROS, serious cell necrosis, reduced activities of SOD and CAT, significantly increased MDA level, obvious leaf wilting, decreased tolerance to infection, and reduced leaf stomatal closure rate and accelerated stomatal area. …"
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21063
Table 1_The relationship between changes in alcohol consumption and hepatic steatosis among alcohol consumers: a large-scale population-based Biobank study.docx
منشور في 2025"…Public health strategies should focus on decreasing alcohol consumption to alleviate the burden of hepatic steatosis.…"
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21064
Data Sheet 1_Brain-derived uroguanylin as a regulator of postprandial brown adipose tissue activation: a potential therapeutic approach for metabolic disorders.docx
منشور في 2025"…In this study, we aim to determine the expression of uroguanylin (UGN) in the mouse and human brain, its regulatory mechanisms, and its significance to patients with obesity and type 2 diabetes (T2D).…"
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21065
Table 6_Immunological reference intervals in pregnancy: longitudinal analysis of adaptive lymphocyte subsets.xlsx
منشور في 2025"…</p>Results<p>Pregnancy was associated with decreased total B cell counts, particularly within transitional and anergic naïve subsets, and increased activated naïve and memory B cells. …"
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21066
Supplementary Material for: Role of Raf Kinase Inhibitor Protein in Modulating Echinococcal Cyst Fluid-induced Degranulation in Bone Marrow-Derived Mast Cells
منشور في 2025"…Following sensitization, BMMCs from the KO group demonstrated significantly higher degranulation rates compared to the WT group (p < 0.05). …"
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21067
Table1_Variation of leaf shape with tree size: a case study using Camptotheca acuminata Decne.xlsx
منشور في 2024"…However, DBH did not significantly affect the ratio W/L nor the leaf roundness index. …"
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21068
Table 7_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx
منشور في 2025"…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…"
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21069
pH sensitive lipid polymeric hybrid nanoparticle (LPHNP) of paclitaxel and curcumin for targeted delivery in breast cancer
منشور في 2024"…MTT-assay studies revealed enhanced cytotoxicity of CUR and PTX as LPHNPs showing IC<sub>50</sub> value of free CUR & PTX 480.06 µg/mL decreasing to 282.97 µg/mL for CS-CUR-PTX-LPHNPs. <i>In vivo</i> pharmacokinetic evaluations in rats confirmed significantly improved bioavailability, with a 3.8-fold increase in AUC for CUR and a 6.6-fold increase for PTX. …"
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21070
Spectral shift of fluorophore NHS-esters.
منشور في 2025"…After 5 min of illumination with a 561-nm excitation laser, the fluorescence signal in the 647-nm detection channel decreased, while the signal in the 561-nm detection channel significantly increased, indicating a spectral blue-shift of the emission spectrum. …"
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21071
Image 2_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.tif
منشور في 2025"…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…"
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21072
Movie 2 Rik<sup>null</sup> vs. WT.
منشور في 2024"…Histological examination of anterior thalamic nuclei demonstrated decreased myelination of anteroventral nuclei but not of anterodorsal nuclei in P23 <i>Rik</i><sup><i>null</i></sup> mice. …"
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21073
Data Sheet 1_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.pdf
منشور في 2025"…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …"
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21074
Table 2_Slavs in the closet: computational genomic analysis reveals cryptic slavic signatures in the Avar Khaganate and their contribution to medieval Croatian population formation...
منشور في 2025"…This approach revealed substantial Baltic genetic components in early Slavic populations (57% in Slovakia/Slovenia) decreasing to 39%–51% in medieval Croatian samples. …"
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21075
Data Sheet 4_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.pdf
منشور في 2025"…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …"
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21076
<b>Liraglutide treatment reverses unconventional cellular defects in induced pluripotent stem cell-derived β cells harboring a partially functional </b><b><i>WFS1</i></b><b> varian...
منشور في 2025"…Pancreatic β cells obtained from patient-derived induced Pluripotent Stem Cells (iPSCs) carrying this <i>WFS1 </i>variant exhibited reduced insulin processing and impaired secretory granule maturation, as evidenced by proinsulin accumulation and decreased prohormone convertase PC1/3. Moreover, they exhibited dysregulated Ca<sup>2+</sup> fluxes due to altered transcription of Ca<sup>2+</sup>-related genes, including <i>CACNA1D</i>, and significantly reduced <i>SNAP25</i> levels, leading to uncoordinated oscillations and poor glucose responsiveness. …"
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21077
Table 1_StACS3-mediated drought stress adaptation in potato involves interactions with StPP2C2 and St14-3-3 proteins.pdf
منشور في 2025"…In contrast, silencing StACS3 significantly reduces stress-induced ethylene accumulation and enhances drought resilience, including decreased cell death and increased antioxidant activity. …"
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21078
Data Sheet 1_Repeated biocide treatments cause changes to the microbiome of a food industry floor drain biofilm model.zip
منشور في 2025"…Analysis of the viable survivors using MALDI-TOF MS and the regrowing biofilms using 16S rRNA amplicon sequencing showed how the diversity of the biofilm decreased but without any change in biocide tolerance as seen in log reductions (CFU/cm<sup>2</sup>). …"
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21079
Table 5_Integrative bulk and single-cell transcriptome analyses reveal integrated stress response-related biomarkers in periodontitis with experimental validation.xlsx
منشور في 2025"…RT-qPCR results confirmed that the expression levels of BTG2, DERL3, FOS, and HSPA13 were significantly upregulated, while YOD1 expression was downregulated in the PD group (P < 0.05), which was consistent with the database-predicted patterns.…"
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21080
Model-derived results show increased social following in individuals with disrupted utility-based risky decision-making.
منشور في 2024"…<b>(d)</b> We tested a link between decreased utility-based risk processing (measured by negative log likelihood in Solo trials; −LL) and increased ω<sub>follow</sub>. …"