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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant threat » significant effect (Expand Search), significant increase (Expand Search)
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18581
SNAP-25 (1-197) binds to syntaxin-1A, and the interaction is enhanced by Ser187 phosphorylation.
Published 2025“…<b>(C and D)</b> PMA treatment further decreases neurotransmitter release when a low level of SNAP-25 cleavage is present. …”
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18582
Supplementary file 2_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx
Published 2025“…The expert authority coefficient (Cr) was 0.86, and the coefficient of variation (CV) for item importance scores decreased across rounds (from 0.07–0.16 in Round 1 to 0.07–0.13 in Round 2), indicating high expert consensus. …”
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18583
Data Sheet 1_The efficacy and safety of panax quinquefolius saponin for heart failure: a systematic review and meta-analysis.pdf
Published 2025“…The results of a meta-analysis under a random-effects model showed that adjuvant PQS therapy significantly increased LVEF (MD = 6.23, 95% CI [4.35, 8.12], P < 0.00001), 6MWTD (MD = 25.26, 95% CI [8.23, 42.30], P = 0.004), and decreased BNP/NT-pro-BNP (MD = −187.94, 95% CI [−267.20, −108.67], P < 0.00001), LVEDV (MD = −22.83, 95% CI [−42.79, −2.87], P = 0.02), LVEDD (MD = −4.76, 95% CI [−5.77, −3.74], P < 0.00001), and LVESV (MD = −11.86, 95% CI [−19.89, −3.83], P = 0.004) in patients with HF.…”
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18584
Table 4_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx
Published 2025“…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …”
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18585
Broader frequency tuning in auditory cortex of <i>Fmr1</i> KO rats despite unaltered subcortical tuning properties.
Published 2025“…**<i>p</i> < 0.01, ***<i>p</i> < 0.0001, ns = not significant. Data and code underlying this figure can be found at <a href="http://doi.org/10.5281/zenodo.15559344" target="_blank">http://doi.org/10.5281/zenodo.15559344</a>. …”
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18586
The role of SLMO in the PSS/PISD pathway.
Published 2024“…(C) SLMO overexpression failed to reverse decreased mitochondrial size from <i>pisd</i><sup><i>RNAi</i></sup> lines. …”
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18587
Supplementary file 6_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx
Published 2025“…The expert authority coefficient (Cr) was 0.86, and the coefficient of variation (CV) for item importance scores decreased across rounds (from 0.07–0.16 in Round 1 to 0.07–0.13 in Round 2), indicating high expert consensus. …”
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18588
Supplementary file 1_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx
Published 2025“…The expert authority coefficient (Cr) was 0.86, and the coefficient of variation (CV) for item importance scores decreased across rounds (from 0.07–0.16 in Round 1 to 0.07–0.13 in Round 2), indicating high expert consensus. …”
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18589
Table 3_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx
Published 2025“…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …”
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18590
Primers used in q-PCR.
Published 2024“…</p><p>Conclusions</p><p>Our study is the first to detect decreased <i>NEAT-1</i> and <i>miR374b-5p</i> expression in COVID-19 patients’ serum. …”
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18591
Principal component analysis of soil parameters.
Published 2025“…The result showed that slope gradients, soil depths, and slope gradients interacting with soil depths had very highly, highly and significant effects on selected soil parameters, exchangeable bases, and extractable micronutrients. …”
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18592
Supplementary file 5_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx
Published 2025“…The expert authority coefficient (Cr) was 0.86, and the coefficient of variation (CV) for item importance scores decreased across rounds (from 0.07–0.16 in Round 1 to 0.07–0.13 in Round 2), indicating high expert consensus. …”
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18593
Supplementary file 4_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx
Published 2025“…The expert authority coefficient (Cr) was 0.86, and the coefficient of variation (CV) for item importance scores decreased across rounds (from 0.07–0.16 in Round 1 to 0.07–0.13 in Round 2), indicating high expert consensus. …”
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18594
Data Sheet 1_Preclinical evidence and potential mechanisms of tanshinone ⅡA on cognitive function in animal models of Alzheimer’s disease: a systematic review and meta-analysis.doc...
Published 2025“…Additionally, it exhibited antiapoptotic effects by increasing the B-cell lymphoma-2/Bcl-2-associated X protein (Bcl-2/Bax) ratio and decreasing Caspase-3 expression. Moreover, treatment improved neuronal/synaptic plasticity by upregulating postsynaptic density-95 (PSD-95) and brain-derived neurotrophic factor (BDNF) levels.…”
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18595
Table 6_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx
Published 2025“…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …”
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18596
Table 1_Elucidating the causal relationship between 486 genetically predicted blood metabolites and the risk of gastric cancer: a comprehensive Mendelian randomization analysis.xls...
Published 2024“…</p>Results<p>The MVMR analysis revealed a significant association between genetically predicted elevated levels of tryptophan (odds ratio [OR] = 0.523, 95% confidence interval [CI] = 0.313–0.872, p = 0.013), nonadecanoate (19:0) (odds ratio [OR] = 0.460, 95% confidence interval [CI] = 0.225–0.943, p = 0.034), and erythritol (odds ratio [OR] = 0.672, 95% confidence interval [CI] = 0.468–0.930, p = 0.016) with a decreased risk of gastric cancer. …”
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18597
Table 1_Time trends in mechanical thrombectomy (2017–2021): do real-world data reflect advances in evidence?.docx
Published 2025“…The use of intravenous thrombolysis decreased (52.4% to 40.4%; p<sub>trend</sub><0.01). …”
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18598
Table 2_Immune-related diagnostic indicators and targeted therapies for COPD combined with NASH were identified and verified via WGCNA and LASSO.xlsx
Published 2025“…Introduction<p>The incidence of chronic obstructive pulmonary disease (COPD) and non-alcoholic fatty liver disease (NAFLD) has increased significantly in past decades, posing a significant public health burden. …”
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18599
Table 1_TCF3 downregulation alleviates renal fibrosis via PI3K/Akt/mTOR pathway inhibition and autophagy restoration in diabetic nephropathy.docx
Published 2025“…Both the DN rat model and HG-stimulated HK-2 cells exhibited enhanced EMT markers, with significantly increased α-SMA and vimentin expression (p < 0.001), and decreased E-cadherin levels (p < 0.001). …”
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18600
A Locally Linear Dynamic Strategy for Manifold Learning.
Published 2025“…In contrast to alignment modulation, the change in the spectrum is largely non-selective. exhibits no significant change for both signal-oriented (blue) and noise-oriented (orange) modes. …”