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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant effect » significant impact (Expand Search)
significant time » significant threat (Expand Search), significant gap (Expand Search)
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19201
A review of geological characteristics and selenium enrichment in Se-bearing volcanogenic massive sulfide deposits
Published 2024“…<p>Volcanogenic massive sulphide (VMS) deposits consist of upper stratabound massive-to-semimassive sulphide lenses and discordant stringer sulphides in the footwall, hosting significant base metals like Zn, Cu, and Pb, with some enriched in precious (Ag, Au) and semi-metals (like Se and Te). …”
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19202
Table1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and coloca...
Published 2024“…While some targeted therapies have been developed, there are still significant challenges in early diagnosis and treatment, highlighting the need to identify new biomarkers and therapeutic targets for breast cancer. …”
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19203
DataSheet1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and co...
Published 2024“…While some targeted therapies have been developed, there are still significant challenges in early diagnosis and treatment, highlighting the need to identify new biomarkers and therapeutic targets for breast cancer. …”
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19204
Image 2_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa...
Published 2025“…Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …”
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19205
Table 5_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx
Published 2025“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”
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19206
Image 1_Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing.tiff
Published 2025“…Although pyroptosis plays a critical role in tumor-immune interactions, its prognostic significance in HCC at single-cell resolution has not been systematically investigated.…”
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19207
Supplementary Material for: Primary Vitreoretinal Lymphomas: A Diagnostic Challenge. Report of two recent cases with retinal biopsies and molecular investigations in Halifax, Nova...
Published 2025“…She had a further decline in her right eye vision with significant extension of the necrotizing retinitis into the macula and optic disc. …”
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19208
Table 5_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx
Published 2025“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”
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19209
<b><i>Original data for "High risk of soil available silicon deficiency in bamboo forest: Insights from bamboo afforestation chronosequences in the karst region of southwest China"...
Published 2025“…Furthermore, aboveground Si content decreased significantly from leaves (10.54–21.45 g kg–1) to branches (3.81–5.61 g kg–1) and culms (1.07–1.98 g kg–1). …”
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19210
Data Sheet 1_Microbial dysbiosis in obstructive sleep apnea: a systematic review and meta-analysis.docx
Published 2025“…Beta diversity analysis indicated significant differences in the gut, respiratory and oral microbial community structure between individuals with OSA and those without in more than half of the included studies. …”
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19211
Data Sheet 1_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..pdf
Published 2025“…The polyphenolic composition of the two cultivars significantly changed depending on the type of LEDs used. …”
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19212
Image 1_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.tif
Published 2025“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”
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19213
Patient disposition.
Published 2025“…Widespread use of the measles vaccine has decreased measles antibody potency in the United States plasma supply. …”
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19214
Table 1_Association between serum anion gap trajectory and mortality in hospitalized patients with sepsis: an analysis of the MIMIC-IV database.docx
Published 2025“…Subgroup analysis revealed a significant interaction between AG trajectories and heart failure status. …”
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19215
Table 12_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx
Published 2025“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”
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19216
Table 1_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf
Published 2025“…</p>Conclusions<p>While significant progress has been made in reducing the global burden of pediatric IE, major geographic and socio-demographic inequalities persist. …”
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19217
Table 3_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf
Published 2025“…</p>Conclusions<p>While significant progress has been made in reducing the global burden of pediatric IE, major geographic and socio-demographic inequalities persist. …”
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19218
DataSheet2_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and co...
Published 2024“…While some targeted therapies have been developed, there are still significant challenges in early diagnosis and treatment, highlighting the need to identify new biomarkers and therapeutic targets for breast cancer. …”
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19219
Data Sheet 1_Elevated Galectin-3 levels in the tumor microenvironment of ovarian cancer – implication of ROS mediated suppression of NK cell antitumor response via tumor-associated...
Published 2024“…In co-cultures with NK cells and K562 target cells, we observed that Galectin-3-induced production of reactive oxygen species in neutrophils resulted in decreased NK cell viability and lowered anti-tumor responses.…”
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19220
Image 1_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff
Published 2025“…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. …”