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significant time » significant threat (Expand Search), significant gap (Expand Search)
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18961
Evolutionarily conserved and functionally important amino acids in Artemis.
Published 2025“…<i>P</i> values were analyzed with Student <i>t</i> test. ns, not significant.</p>…”
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18962
Rutin attenuates iron overload induced-ferroptosis in rats’ heart tissue
Published 2025“…After rutin treatment, our results revealed that TIBC, ferritin, transferrin, hepicidin, MDA&NO were significantly decreased, while GSH level and GPx&SOD activities were significantly increased. …”
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18963
Data Sheet 1_Impact of a multifaceted intervention including a smart reminder system for intraoperative antibiotic re-dosing on surgical site infections in a Chinese tertiary care...
Published 2025“…The proportion of intraoperative additional antibiotic administration also increased significantly (p = 0.003). Furthermore, the rate of SSIs decreased significantly after the intervention (p = 0.038).…”
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18964
Plant species loss reduces rare soil microbes through diversity effect amplified by multitrophic interactions
Published 2025“…We found that the removal of rare forbs, rather than dominant species and common plants, significantly decreased the richness of soil bacteria and fungi by decreasing rare microbial taxa in later years. …”
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18965
Table 1_Changes in the energy metabolism of the gills of Litopenaeus vannamei under carbonate alkalinity stress and recovery conditions.doc
Published 2025“…In detail, after CA stress, carbohydrate metabolism related indexes, the pyruvate (PYR) content showed increases, as did the relative expression of the hk, pk, and pdh genes, while the glucose (GLU) and lactate (LAC) content and the expression of the idh gene were slightly decreased; lipid metabolism related indexes, such as the triglycerides (TG) content and the expression of the ampk gene were slightly increased, and the expressions of the srebp, acc, and fas genes were increased significantly; tricarboxylic acid (TCA) cycle related indexes, such as the expressions of the cs, odh, and sdh genes were up-regulated, whereas the expressions of the mdh and idh genes were significantly down-regulated, the expression of the fh gene was slightly decreased in regulation; electron transfer chain related indexes, such as the expressions of the ndh, cytc, coi, cco, and atph genes were significantly increased. …”
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18966
Deactivation mechanism of catalyst in long-period experiment of 1,1,2-TCE dehydrochlorination
Published 2024“…The results indicated that the catalyst life had been significantly improved. In the early stage of the reaction, the activity of the catalyst decreased rapidly. …”
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18967
Ybx1 regulation of its target mRNAs is m<sup>5</sup>C-depdendent (Related to Fig 5).
Published 2025“…<p><b>(A)</b> RT-qPCR confirmed the decreased expression levels of Ybx1 target mRNAs in neural stem cells with Ybx1 knockdown using siRNA. …”
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18968
Shapley Additive Explanations (SHAP) summary plot.
Published 2025“…(B) SHAP Bees Plot, The SHAP values are distributed along the horizontal axis, where positive values indicate that the feature increases the predicted outcome, and negative values indicate that it decreases the predicted outcome. …”
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18969
Data Sheet 1_Influence of specific tobacco endophytic Bacillus on tobacco leaf quality enhancement during fermentation.pdf
Published 2024“…Chemical analysis revealed that fermentation with B. halotolerans NS36 significantly decreased the content of irritant compounds such as lignin, cellulose, starch, and pectin. …”
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18970
Table 1_Targeting nail psoriasis: IL-17A inhibitors demonstrate site-specific superiority over IL-23 inhibitor in a 24-week dermoscopy-guided real-world cohort.docx
Published 2025“…</p>Results<p>(1) By week 24, PASI, BSA, DLQI and NAPSI scores had significantly decreased from baseline in all groups (P<0.001). (2) By week 24: SEC, IXE, and GUS groups saw nail matrix NAPSI score improvements of 65.9%, 60.5%, and 51.5%, with 68%, 55%, and 30% achieving NAPSI 60; Nail bed NAPSI score improvements were 58.8%, 68.6%, and 65.8%, with 28%, 65%, and 40% achieving NAPSI 60; Total NAPSI score improvements were 62.7%, 64.6%, and 53.7%, with 44%, 70%, and 30% achieving NAPSI 60. (3) All patients in the SEC and IXE groups achieved PASI 75, compared to 85% in the GUS group. …”
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18971
Data Sheet 1_Cross-species analysis of FcγRIIa/b (CD32a/b) polymorphisms at position 131: structural and functional insights into the mechanism of IgG- mediated phagocytosis in hum...
Published 2025“…In contrast, allele-specific effects in macaques were highly significant; the macaque P<sup>131</sup> variant showing uniformly reduced IgG affinity. …”
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18972
Experimental protocol and behavioral evidence of perceptual learning.
Published 2025“…The shaded area represents the standard error of the mean. Significant clusters for the main effect of PRE/post training, as determined by cluster mass permutation two-tailed tests, are indicated with rectangles (p < 0.05 and p < 0.1). …”
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18973
Genetic and structural factors contributing to the dominance and persistence of goose astrovirus type 2
Published 2025“…<p>Goose astrovirus (GoAstV) has emerged as a significant pathogen affecting the goose industry in China, with GoAstV-2 becoming the dominant genotype since 2017. …”
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18974
Data Sheet 1_Efgartigimod for generalized myasthenia gravis in the extreme elderly (≥80 years): a multicenter retrospective real-world study.pdf
Published 2025“…At week 4 (1week after the final infusion), the study showed significant reductions in all efficacy measurements: MG-ADL scores decreased by 52.2% ± 30.8% (from 10.9 ± 2.7 to 3.6 ± 2.1), QMG scores by 36.6% ± 28.4% (from 18.2 ± 7.0 to 11.7 ± 8.3), MGC scores by 48.2% ± 33.4% (from 17.8 ± 7.5 to 9.0 ± 8.6). …”
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18975
Data sources and descriptions.
Published 2025“…As the results show, during the study period: (1) Temporal Trends: annual PM2.5 concentrations exhibited significant declines, with BTH decreasing from 1004.71 μg/m<sup>3</sup> (2006) to 528 μg/m<sup>3</sup> (2020), YRD from 1434.81 μg/m<sup>3</sup> (2008) to 621 μg/m<sup>3</sup>, and PRD from 405.02 μg/m<sup>3</sup> (2007) to 292 μg/m<sup>3</sup>. …”
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18976
Table 1_Genetic diversity and antibiotic resistance of Mycobacterium bovis in bovines in the Delta area of Egypt.docx
Published 2025“…Introduction<p>Mycobacterium bovis (M. bovis) causes significant financial harm to the cattle industry through decreased productivity and trade limitations, while also posing a risk to human health through zoonotic transmission, which is primarily from unpasteurized milk or close animal contact.…”
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18977
Table 1_Glucose and lipid metabolism in non-diabetic, non-obese patients with obstructive sleep apnea: sex differences.docx
Published 2025“…The high-density lipoprotein cholesterol (HDL-C) level in OSA participants was significantly lower (0.99 vs. 1.12 mmol/L, p = 0.036), and the triglyceride-glucose (TyG) index was significantly higher (8.74 vs. 8.45, p = 0.016), while there was no significant difference in the levels of total cholesterol, low-density lipoprotein cholesterol (LDL-C), and non-HDL-C. …”
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18978
DataSheet1_Genetic variants of LRRC8C, OAS2, and CCL25 in the T cell exhaustion-related genes are associated with non-small cell lung cancer survival.doc
Published 2024“…Background<p>T cell exhaustion is a state in which T cells become dysfunctional and is associated with a decreased efficacy of immune checkpoint inhibitors. …”
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18979
Table1_Genetic variants of LRRC8C, OAS2, and CCL25 in the T cell exhaustion-related genes are associated with non-small cell lung cancer survival.docx
Published 2024“…Background<p>T cell exhaustion is a state in which T cells become dysfunctional and is associated with a decreased efficacy of immune checkpoint inhibitors. …”
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18980
Table 1_Prior Trichinella spiralis infection protects against Schistosoma mansoni induced hepatic fibrosis.docx
Published 2024“…Furthermore, pre- infection with T. spiralis markedly reduced S. mansoni- induced hepatic fibrosis, as evidenced by decreased collagen deposition, low expression of α-SMA, and significantly reduced levels of IL-17, IL-1B, IL-6, TGF-B, IL-23, and TNF-α compared to mice infected with S. mansoni only.…”