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significant trend » significant threat (Expand Search), significant threats (Expand Search), significant burden (Expand Search)
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20841
Data Sheet 11_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf
Published 2025“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”
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20842
Table 7_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.xlsx
Published 2025“…Wheat seed inoculation significantly enhanced germination metrics, seedling vigor, and altered carbohydrate metabolism in the seed endosperm. …”
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20843
Data Sheet 1_BMP9 induces postnatal zonal stratification of immature articular cartilage through reconfiguration of the existing collagen framework.pdf
Published 2025“…In explants exposed to BMP9, collagen fibrils underwent angular displacement from 19° to 78° with respect to the surface, cell density decreased 1.77-fold, and chondrons were significantly larger. …”
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20844
Supplementary file 1_Ultrafine garlic powder alleviates non-alcoholic steatohepatitis by inhibiting hepatocyte ferroptosis and modulating ERK-dependent oxidative stress.docx
Published 2025“…Fibrosis-related mRNA and pro-inflammatory mRNA expression were significantly decreased. Western blot results showed that UGP significantly inhibited the activation of p-ERK signaling. …”
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20845
supplementary figure: Osimertinib inhibits the MYLK4-mediated phosphorylation of CDKAL1 to suppress stemness and chemoresistance in rhabdomyosarcoma
Published 2025“…The RT‒PCR data are presented as the means ± SDs (n = 3). Statistical significance: ns, p ≥ 0.05. (right): Self-renewal capacity (n = 4) of RD cells treated with osimertinib. …”
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20846
Image 1_TSLP pretreatment inhibits M1 macrophage polarization and attenuates LPS-induced iNKT cell-dependent acute lung injury.pdf
Published 2025“…In addition, TSLP treatment significantly inhibited M1 macrophage polarization and promoted M2 macrophage differentiation. …”
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20847
Supplementary Material for: Retrospective Analysis of Allergen Characteristics in Patients with Allergic Diseases in Sanmen, Zhejiang Province
Published 2025“…The positivity rate for serum total IgE was 25.67%, significantly higher than the IgE prevalence of inhalant allergens (24.84%) and food allergens (12.48%), significantly higher than the positivity rate for food allergen sIgE at 12.48% (P<0.001). …”
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20848
Data Sheet 1_Artificial intelligence-assisted delineation for postoperative radiotherapy in patients with lung cancer: a prospective, multi-center, cohort study.docx
Published 2024“…In addition to better contouring accuracy, the AI-assisted delineation significantly decreased the consuming time and improved the efficiency.…”
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20849
Supplementary file 1_To assess the impact of individualized strategy and continuous glucose monitoring on glycemic control and mental health in pregnant women with diabetes.docx
Published 2025“…</p>Results<p>FBG and 2hPBG significantly decreased post-intervention in both groups (P<0.001). …”
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20850
Table 1_Exhaled breath particles as a diagnostic tool for bronchiolitis obliterans syndrome in lung transplant recipients: a longitudinal study.docx
Published 2025“…The particle distribution between the different BOS grades had a similar pattern; however, it significantly decreased PFR with severity in the BOS grade.…”
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20851
Data Sheet 1_Susceptibility to and severity of tuberculosis infection in mice depends upon MHC-II-determined level of activation-inhibition balance in CD4 T-cells.pdf
Published 2025“…<p>Previously we have shown that H2-congenic recombinant mice of the B6.I-9.3 (H2-Ab1<sup>j</sup>) strain are significantly more susceptible to tuberculosis (TB) infection compared to their C57BL/6 (B6, H2-A<sup>b</sup>) ancestors. …”
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20852
Table 4_Genome-wide association study of seedling–plant resistance to stripe rust in bread wheat (Triticum aestivum L.) genotypes.xls
Published 2025“…<p>Fungal diseases, such as stripe rust, are major bottlenecks in Ethiopian wheat production. They can significantly reduce yields and impact regional food security. …”
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20853
Table 1_Investigating the Gut Microbiota Profile in Prehypertensive Individuals Exhibiting Phlegm-Dampness Constitution.docx
Published 2025“…</p>Results<p>At the phylum level, the abundance of Bacteroidetes decreased in the PDC group compared with the NPDC group. …”
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20854
Data Sheet 2_Bifidobacterium depletion promotes goiter via gut-thyroid axis: evidence from Mendelian randomization and experimental validation.xlsx
Published 2025“…In goiter rats, 16S rRNA sequencing revealed eight differentially abundant microbial taxa including significantly reduced B. bifidum, accompanied by: (1) impairment of two butyrate synthesis pathways, (2) decreased levels of six SCFAs (including butyrate), (3) impaired thyroid iodine uptake, (4) downregulated NIS expression, and (5) thyroid dysfunction [reduced triiodothyronine (T3), thyroxine (T4), free T3 (FT3), free T4 (FT4) with elevated thyroid-stimulating hormone (TSH)] - all measurements showing statistical significance (p < 0.05).…”
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20855
Presentation 1_CD26 as a potential therapeutic target for lung adenocarcinoma.pptx
Published 2025“…We demonstrated before that CD26 inhibition decreases lung tumor growth in experimental models. …”
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20856
Table 1_CD26 as a potential therapeutic target for lung adenocarcinoma.docx
Published 2025“…We demonstrated before that CD26 inhibition decreases lung tumor growth in experimental models. …”
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20857
Table 5_Genome-wide association study of seedling–plant resistance to stripe rust in bread wheat (Triticum aestivum L.) genotypes.xls
Published 2025“…<p>Fungal diseases, such as stripe rust, are major bottlenecks in Ethiopian wheat production. They can significantly reduce yields and impact regional food security. …”
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20858
Data_Sheet_1_miR-124 Alleviates Ischemic Stroke-Induced Neuronal Death by Targeting DAPK1 in Mice.docx
Published 2025“…</p>Results<p>In vivo and in vitro results demonstrated that levels of miR-124 were significantly decreased following stroke, whereas changes in death-associated protein kinase 1 (DAPK1) levels exhibited the converse pattern. …”
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20859
Table 6_Genome-wide association study of seedling–plant resistance to stripe rust in bread wheat (Triticum aestivum L.) genotypes.xls
Published 2025“…<p>Fungal diseases, such as stripe rust, are major bottlenecks in Ethiopian wheat production. They can significantly reduce yields and impact regional food security. …”
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20860
Table 1_Autophagy crosstalk with the immune microenvironment in chronic myeloid leukemia and serves as a biomarker for diagnosis and progression.xlsx
Published 2025“…</p>Results<p>Compared with normal samples, CML samples had significantly lower autophagy scores and more downregulated ARGs. …”