Table 3_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf by Ying Xiao (6517)

“…</p>Results<p>Globally, the incidence of pediatric IE declined by 27.6% (95% UI, −30.9% to −24.9%) and mortality by 21.4% (95% UI, −35.2% to −0.8%) between 1990 and 2021, with an estimated annual percentage change (EAPC) of −1.37% (95% CI, −1.49% to −1.24%) and −0.64% (95% CI, −0.75% to −0.54%), respectively. DALYs decreased by 19.2% (95% UI, −33.2% to 1.9%). Marked disparities persisted, with high-SDI regions, notably China, achieving the greatest reductions in burden, while sub-Saharan Africa and Eastern Europe exhibited stagnant or increasing rates. …”

Data Sheet 4_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.pdf by Christina Stevens (9737867)

“…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. However, only age, hindlimb joint pain, and hindlimb muscle atrophy had statistically significant effects on physical activity.…”

Image2_Hypothermia amongst neonatal admissions in Kenya: a retrospective cohort study assessing prevalence, trends, associated factors, and its relationship with all-cause neonatal... by John Wainaina (12554691)

“…Background<p>Reports on hypothermia from high-burden countries like Kenya amongst sick newborns often include few centers or relatively small sample sizes.…”

Data Sheet 5_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.pdf by Christina Stevens (9737867)

“…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. However, only age, hindlimb joint pain, and hindlimb muscle atrophy had statistically significant effects on physical activity.…”

Image 1_Multi-omics analysis reveals indicator features of microbe-host interactions during Candida albicans colonization and subsequent infection.tif by Huan Zhang (220065)

“…</p>Importance<p>Candida albicans invasive infections pose a significant challenge to contemporary medicine, with mortality rates from such fungal infections remaining high despite antifungal treatment. …”

IL-1<i>β</i>-mediated TGFβ/SMAD signaling pathway inactivation impaired <i>ex vivo</i> osteogenic activity of human bone marrow-derived stromal cells by Amer Mahmood* (11274400)

“…Interestingly, IL1β is highly expressed in hBMSC^−Bone and is present in its CM. …”

Image_2_Measuring the inequalities in healthcare resource in facility and workforce: A longitudinal study in China.JPEG by Enhong Dong (10812742)

“…</p>Results<p>Shanghai's healthcare resources showed decreasing trends of inequalities at large from 2010 to 2016. …”

Image5_Comprehensive analysis of m7G modification patterns based on potential m7G regulators and tumor microenvironment infiltration characterization in lung adenocarcinoma.TIF by Shouzheng Ma (12264398)

“…We further demonstrated the m⁷Gscore could predict the TME infiltrating characteristics, tumor mutation burden (TMB), response to immunotherapy and chemotherapy, as well as prognosis of individual tumors. High m⁷Gscore was associated with increased component of immune cell infiltration, low TMB and survival advantage, while low m⁷Gscore was linked to decreased immune cell infiltration and increased TMB. …”

Table_1_Anti-TNF Drugs for Chronic Uveitis in Adults—A Systematic Review and Meta-Analysis of Randomized Controlled Trials.pdf by Inês Leal (5996858)

“…</p><p>Conclusions: There is high quality evidence that adalimumab decreases the risk of worsening VA in active and inactive NIU and very low quality evidence that the risk of etanercept worsening VA in inactive NIU is not different from placebo. …”

Image_3_Measuring the inequalities in healthcare resource in facility and workforce: A longitudinal study in China.JPEG by Enhong Dong (10812742)

“…</p>Results<p>Shanghai's healthcare resources showed decreasing trends of inequalities at large from 2010 to 2016. …”

DataSheet1_Kalpra: A kernel approach for longitudinal pathway regression analysis integrating network information with an application to the longitudinal PsyCourse Study.docx by Bernadette Wendel (12027083)

“…<p>A popular approach to reduce the high dimensionality resulting from genome-wide association studies is to analyze a whole pathway in a single test for association with a phenotype. …”

Datasheet2_Identification of Important Modules and Biomarkers That Are Related to Immune Infiltration Cells in Severe Burns Based on Weighted Gene Co-Expression Network Analysis.XL... by Zexin Zhang (7507979)

“…<p>Background: Immunosuppression is an important trigger for infection and a significant cause of death in patients with severe burns. …”

seNorge_2018 observational gridded datasets over Norway by Cristian Lussana (7380143)

“…., land-area fraction is in the spatial structure function) and an improved parameter optimization procedure. The results show significant differences from the previous version, especially along the coastline and in data-sparse regions. …”

Table_2_From Function to Metabolome: Metabolomic Analysis Reveals the Effect of Probiotic Fermentation on the Chemical Compositions and Biological Activities of Perilla frutescens... by Zhenxing Wang (201180)

“…Further metabolomic analysis revealed significant metabolite changes under the best fermentation condition, which involved primarily the generation of fatty acids and their conjugates, flavonoids. …”

Data_Sheet_1_Extracutaneous features and complications of the Ehlers-Danlos syndromes: A systematic review.docx by Brent J. Doolan (14490089)

“…The most common musculoskeletal complications were decreased bone density (39/43, 90.7%), joint pain (217/270, 80.4%), and hypotonia/weakness (79/140, 56.4%). …”

DataSheet_1_CXCL8 Associated Dendritic Cell Activation Marker Expression and Recruitment as Indicators of Favorable Outcomes in Colorectal Cancer.pdf by Enhao Li (10762086)

“…Here, we identified the TME-related gene CXCL8 in a high-ImmuneScore population that contributed to better survival in colorectal cancer (CRC) patients from The Cancer Genome Atlas (TCGA) database. …”

Table_1_Compassion-Focused Group Therapy for Treatment-Resistant OCD: Initial Evaluation Using a Multiple Baseline Design.DOCX by Nicola Petrocchi (9971198)

“…Participants reported high levels of acceptability of and satisfaction with the intervention. …”

Data Sheet 3_Divergent trends and regional disparities in PM2.5 and O3 health economic burdens in China, 2013–2023: an integrated assessment with policy implications.zip by Ziqi Tang (10904159)

“…Spatially, health economic costs and their GDP proportions for both pollutants followed a high distribution in the east and a low distribution in the west. …”

Study on the correlation between maternal serum uric acid and foetal birth weight in Naqu, Tibet by Yong-Chang Yang (14552737)

“…<p>In high-altitude regions, low birth weight is mainly caused by hypoxia. …”

Data_Sheet_3_MicroRNA–Messenger RNA Regulatory Network Mediates Disrupted TH17 Cell Differentiation in Depression.xlsx by Haiyang Wang (22389)

“…Functional analysis of the intersecting differentially expressed mRNAs revealed that an abnormal inflammatory response characterized by disturbed T-helper cell 17 (Th17) differentiation was the primary altered biological function. qRT-PCR validated the decreased expression of Th17 cell differentiation-related genes, including interleukin (IL)17A, IL21, IL22, and IL1β, and the increased expression of retinoic acid receptor-related orphan receptor gamma-t (RORγt) in CSDS mice, which showed significant depressive- and anxiety-like behaviors. …”