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2301
Data Sheet 1_Treatment with pemafibrate ameliorates fatty liver index and atherogenic lipid profiles in Japanese patients with type 2 diabetes mellitus.pdf
Published 2025“…</p>Results<p>Treatment with pemafibrate significantly increased mean levels of high-density lipoprotein cholesterol (HDL-C) (baseline/3M/6M/12M: 46/55/55/54 mg/dL) and decreased median levels of triglycerides (baseline/3M/6M/12M: 211/112/99/98 mg/dL), non-HDL-C (146/128/125/121 mg/dL), small dense low-density lipoprotein cholesterol (45/33/30/30 mg/dL) and remnant-like particle cholesterol (8.1/2.6/2.3/2.4 mg/dL). …”
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2302
The proportion of the dosage of tenapanor.
Published 2025“…<div><p>Introduction</p><p>Tenapanor is a minimally absorbed, small-molecule inhibitor of sodium/hydrogen exchanger 3 and thus suppresses sodium absorption in the gastrointestinal tract. …”
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2303
Image_1_A sexually dimorphic signature of activity-dependent BDNF signaling on the intrinsic excitability of pyramidal neurons in the prefrontal cortex.TIF
Published 2024“…Further, the amplitudes of mAHP were significantly decreased in male BDNF<sup>+/Met</sup> mice only, which were mediated by the downregulation of Kcnn2 encoding small conductance calcium-activated potassium channel 2 (SK2). …”
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2304
Supplementary Tables 1-7 from Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer
Published 2025“…Number of motifs 10kbp from MHC Class I processing genes that were targeted by a small library CRISPR screen. Table S4A. GSEA Pathway analysis from dataset in Figure 4A. …”
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2305
Supplementary Tables 1-7 from Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer
Published 2025“…Number of motifs 10kbp from MHC Class I processing genes that were targeted by a small library CRISPR screen. Table S4A. GSEA Pathway analysis from dataset in Figure 4A. …”
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2306
Image 5_Selective inhibition of canonical STAT3 signaling suppresses K-ras mutant lung tumorigenesis and reinvigorates anti-tumor immunity.tif
Published 2025“…</p>Methods<p>Here, we tested the anti-tumor and early immunotherapeutic efficacy of TTI-101, a selective small-molecule inhibitor of canonical STAT3 signaling, in a K-ras<sup>G12D</sup> mutant lung cancer mouse model (CC-LR).…”
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2307
Data Sheet 2_Identification of potential miRNA biomarkers for neurobrucellosis diagnosis.pdf
Published 2025“…This study aimed to analyze the microRNA (miRNA) profile of cerebrospinal fluid (CSF) in NB patients to identify potential biomarkers for NB diagnosis.</p>Methods<p>Small RNA sequencing was utilized to identify differential expressed miRNAs (DEmiRNAs) in CSF samples from both control and NB patients (in-house cohort). …”
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2308
Image 2_A natural PCID2-Targeting compound suppresses hepatocellular carcinoma progression: evidence from structure-based discovery and biological evaluation.jpeg
Published 2025“…Mechanistically, β-PGG decreased PCID2 expression and downregulated Cyclin D1 and CDK6. …”
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2309
Table 1_Working like a mule? The physiological toll of heavy loads on mules.docx
Published 2025“…Conversely, glutathione peroxidase (GPx) activity decreased as load increased, implying increased oxidative demand. …”
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2310
Data Sheet 1_Synthesis of oligo-α-(1→2)-4,6-dideoxy-4-formamido-d-mannopyranosides related to the A epitope of the Brucella O-polysaccharide and their use for assaying of serum imm...
Published 2025“…This observation demonstrates the advantages of using synthetic relatively small synthetic tracers with well-defined structure in comparison with heterogeneous fluorescein-labelled O-polysaccharides which are in use today in spite of the fact that they contain poorly characterized amounts of label attached along the polysaccharide chains.…”
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2311
Numerical data underlying the graphs.
Published 2025“…<i>DANCR</i> is a multi-exonic, cytoplasmically-enriched lncRNA and small RNA host gene transcribed from syntenic regions in the human and zebrafish genomes. …”
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2312
DataSheet1_Shenshuaikang enema restores the intestinal barrier and microbiota-gut-kidney axis balance to alleviate chronic kidney disease via NF-κB pathway.docx
Published 2025“…</p>Results<p>We found that SSKE improves renal function, attenuates renal fibrosis, reduces inflammatory factor levels, and decreases damage to intestinal and renal structures in adenine-induced CKD rats. …”
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2313
Data Sheet 1_Long-term evolution of forest cover in the Pacific coast of Ecuador (1960–2019): a comparison of Land Use/Land Cover (LULC) remote sensing products.pdf
Published 2025“…In addition, previous studies on the evolution of the forest cover in the EPSC were achieved on small regions and short time-scales, never analysing before the 1990s. …”
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2314
Computational fluid dynamics of particles’ transport in the airways (Vuorinen et al., 2025)
Published 2025“…The results therefore suggest that infections in lower airways may transmit primarily via small particles. This should be considered when planning suitable protective measures.…”
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2315
Supplementary file 1_A natural PCID2-Targeting compound suppresses hepatocellular carcinoma progression: evidence from structure-based discovery and biological evaluation.docx
Published 2025“…Mechanistically, β-PGG decreased PCID2 expression and downregulated Cyclin D1 and CDK6. …”
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2316
Image 4_Selective inhibition of canonical STAT3 signaling suppresses K-ras mutant lung tumorigenesis and reinvigorates anti-tumor immunity.tif
Published 2025“…</p>Methods<p>Here, we tested the anti-tumor and early immunotherapeutic efficacy of TTI-101, a selective small-molecule inhibitor of canonical STAT3 signaling, in a K-ras<sup>G12D</sup> mutant lung cancer mouse model (CC-LR).…”
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2317
Table 1_Identification of potential miRNA biomarkers for neurobrucellosis diagnosis.xlsx
Published 2025“…This study aimed to analyze the microRNA (miRNA) profile of cerebrospinal fluid (CSF) in NB patients to identify potential biomarkers for NB diagnosis.</p>Methods<p>Small RNA sequencing was utilized to identify differential expressed miRNAs (DEmiRNAs) in CSF samples from both control and NB patients (in-house cohort). …”
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2318
Image 2_Selective inhibition of canonical STAT3 signaling suppresses K-ras mutant lung tumorigenesis and reinvigorates anti-tumor immunity.tif
Published 2025“…</p>Methods<p>Here, we tested the anti-tumor and early immunotherapeutic efficacy of TTI-101, a selective small-molecule inhibitor of canonical STAT3 signaling, in a K-ras<sup>G12D</sup> mutant lung cancer mouse model (CC-LR).…”
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2319
Table3_Treatment of refractory immune-mediated necrotizing myopathy with efgartigimod.docx
Published 2024“…</p>Conclusions<p>Despite its small size, our study demonstrated that promoting the degradation of endogenous immunoglobulin G may be effective for patients with IMNM. …”
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2320
Table 1_Obstetric and perinatal outcomes in pregnancies conceived with donor versus partner sperm: a systematic review and meta-analysis.docx
Published 2025“…For other outcomes, including gestational diabetes mellitus, ectopic pregnancy, placental abruption, placenta previa, large and small for gestational age, preterm birth, high and low birth weight, perinatal death, stillbirth, neonatal death, and congenital anomalies, no significant disparities were observed.…”