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1681
Image1_Honokiol protects against diabetic retinal microvascular injury via sirtuin 3-mediated mitochondrial fusion.TIF
منشور في 2024"…Introduction<p>Mitochondrial dysfunction and oxidative stress play important roles in diabetic retinal vascular injuries. Honokiol (HKL) is a small-molecule polyphenol that exhibits antioxidant effects and has a beneficial effect in diabetes. …"
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1682
Image1_Honokiol protects against diabetic retinal microvascular injury via sirtuin 3-mediated mitochondrial fusion.TIF
منشور في 2024"…Introduction<p>Mitochondrial dysfunction and oxidative stress play important roles in diabetic retinal vascular injuries. Honokiol (HKL) is a small-molecule polyphenol that exhibits antioxidant effects and has a beneficial effect in diabetes. …"
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1683
Complexity comparison of different models.
منشور في 2025"…The computational complexity of the improved model decreased dramatically, but the average classification accuracy was only 1.6% lower than that before the improvement. …"
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1684
Dynamic window based median filtering algorithm.
منشور في 2025"…The computational complexity of the improved model decreased dramatically, but the average classification accuracy was only 1.6% lower than that before the improvement. …"
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1685
Flow of operation of improved KMA.
منشور في 2025"…The computational complexity of the improved model decreased dramatically, but the average classification accuracy was only 1.6% lower than that before the improvement. …"
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1686
Improved DAE based on LSTM.
منشور في 2025"…The computational complexity of the improved model decreased dramatically, but the average classification accuracy was only 1.6% lower than that before the improvement. …"
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1687
Autoencoder structure.
منشور في 2025"…The computational complexity of the improved model decreased dramatically, but the average classification accuracy was only 1.6% lower than that before the improvement. …"
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1688
Detailed evaluation of the automated cell counting method.
منشور في 2024"…<p>(A) The evaluation of the automatic cell counting performance using the validation dataset (603 counting boxes). …"
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1689
KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity
منشور في 2024"…</p> <p><b>Abbreviations</b>: 3-MA: 3-methyladenine; AAV: adeno-associated virus; ACTB: actin beta; AGC: automatic gain control; ATG: autophagy-related; ATP6V0D1: ATPase H<sup>+</sup> transporting lysosomal V0 subunit D1; ATP6V1E1: ATPase H<sup>+</sup> transporting lysosomal V1 subunit E1; CA: cornu ammonis; CQ: chloroquine; CTSB: cathepsin B; CTSD: cathepsin D; DCTN1: dynactin subunit 1; DG: dentate gyrus; DYNLL1: dynein light chain LC8-type 1; FBS: fetal bovine serum; GABARAP: GABA type A receptor-associated protein; GABARAPL1: GABA type A receptor associated protein like 1; GABARAPL2: GABA type A receptor associated protein like 2; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; IPA: Ingenuity Pathway Analysis; KEGG: Kyoto Encyclopedia of Genes and Genomes; KIF5A: kinesin family member 5A; LAMP: lysosomal-associated membrane protein; MAP1LC3B/LC3B: microtubule-associated protein 1 light chain 3 beta; NBR1: NBR1 autophagy cargo receptor; OPTN: optineurin; PBS: phosphate-buffered saline; PFA: paraformaldehyde; PIK3C3/VPS34: phosphatidylinositol 3-kinase catalytic subunit type 3; PRM: parallel reaction monitoring; siRNA: small interfering RNA; SQSTM1/p62: sequestosome 1; SYP: synaptophysin; TAX1BP1: Tax1 binding protein 1; TMT: trimethyltin chloride; TUB: tubulin.…"
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1690
<i>B. bassiana</i>-induced cell loss requires Wek, but Wek has pleiotropic functions.
منشور في 2025"…<b>(F, G)</b> Adult-specific <i>wek-RNAi</i><sup><i>JF01681</i></sup> knockdown decreased the number of TH + PPM3 DANs (arrows in F), suggesting that <i>wek</i> may be required for their differentiation. …"
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1691
Pond consolidation in the northwest Prairie Pothole Region changes water boatman (Hemiptera: Corixidae) species composition and reduces potential contribution to seasonal mass-migr...
منشور في 2025"…We found a non-significant decrease in species richness due to pond consolidation. …"
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1692
Table 1_A low-protein soybean-free diet improves carcass traits and meat quality and modulates the colonic microbiota in Daweizi pigs.docx
منشور في 2025"…In addition, the LPNS diet significantly increased leanness and decreased the fat-skin rate and bone rate of Daweizi pigs. …"
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1693
Influence of fly ash and granulated blast furnace slag on autogenous shrinkage and drying shrinkage of cement-based materials mixed with alkali accelerator and alkali-free accelera...
منشور في 2024"…<p>Shotcrete shrinkage and cracking are getting more threatening due to its high content of cementitious materials, small aggregate particle size and a large amount of accelerator, which poses a great threat to the construction safety of engineering structures. …"
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1694
<b>Effect of Marked Weight Loss on Adipose Tissue Biology in People with Obesity and Type 2 Diabetes</b>
منشور في 2025"…</p><p dir="ltr"><b>Results: </b>Weight loss: <a href="" target="_blank">i) </a><a href="" target="_blank">decreased adipose tissue </a>expression of genes related to extracellular matrix remodeling; ii) decreased adipose tissue expression of SERPINE 1 which encodes plasminogen activator inhibitor-1 (PAI-1); iii) did not decrease adipose tissue immune cell content or expression of genes involved in inflammation; iv) decreased adipose tissue ceramide content; v) decreased plasma <a href="" target="_blank">PAI-1 </a>and leptin concentrations and increased plasma high-molecular weight (HMW) adiponectin; and vi) decreased plasma small extracellular vesicle (sEV) concentration and the sEV content of microRNAs proposed to inhibit insulin action, and completely reversed the inhibitory effect of plasma sEVs on insulin signaling in myotubes.…"
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1695
Base-case analysis results.
منشور في 2024"…Most model input changes did not decrease the ICER of sintilimab plus IBI305 and chemotherapy below the upper WTP threshold. …"
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1696
Antibodies used in this study.
منشور في 2024"…In this study, we performed a proteomic assessment of differentially regulated proteins from CF and non-CF small airway epithelial cells (SAEC) that are sensitive to <i>Mycobacterium avium</i>. …"
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1697
Supplementary Material for: Healing Diabetic Foot Ulcers with Topical Timolol Improves Healed Epithelial Integrity
منشور في 2025"…The use of a wheelchair was also associated with a significant decrease in transepidermal water loss (Estimate = -7.7, p=0.01). …"
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1698
Time and flowrate used for proteomics.
منشور في 2024"…In this study, we performed a proteomic assessment of differentially regulated proteins from CF and non-CF small airway epithelial cells (SAEC) that are sensitive to <i>Mycobacterium avium</i>. …"
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1699
RbmB digests VPS <i>in vitro</i>.
منشور في 2024"…Increasing amounts of RbmB show a decrease in the aggregates and increase in free Bap1, suggesting cleavage of VPS into small fragments. …"
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1700
DtpT transports structurally diverse di-/tripeptides.
منشور في 2025"…Upon induction of negative-inside ΔΨ by addition of valinomycin, DtpT transports peptides (small circles) from the external environment into the liposome lumen. …"