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Linker Optimization Enhances the Potency of Ribonuclease-Targeting Chimeras in Cancer Models
Published 2025Subjects: -
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Long-term divergence of nitrogen and phosphorus dynamics in small lakes across China
Published 2025“…Using 220,832 water quality records from 208 national automatic monitoring stations and 17 auxiliary variables, we applied a Random Forest model to predict monthly TN and TP concentrations for 18,210 small lakes from 2000 to 2020. …”
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Image 2_G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo.tif
Published 2024“…The mechanism is poorly understood due to the lack of small animal models.</p>Methods<p>Mice were inoculated with 10<sup>7</sup> CFU of the eubiotic bacteria Lactobacillus crispatus, the dysbiotic bacteria G. vaginalis, or PBS as a negative control every 48 h for ten days. …”
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Image 5_G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo.tif
Published 2024“…The mechanism is poorly understood due to the lack of small animal models.</p>Methods<p>Mice were inoculated with 10<sup>7</sup> CFU of the eubiotic bacteria Lactobacillus crispatus, the dysbiotic bacteria G. vaginalis, or PBS as a negative control every 48 h for ten days. …”
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Image 3_G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo.tif
Published 2024“…The mechanism is poorly understood due to the lack of small animal models.</p>Methods<p>Mice were inoculated with 10<sup>7</sup> CFU of the eubiotic bacteria Lactobacillus crispatus, the dysbiotic bacteria G. vaginalis, or PBS as a negative control every 48 h for ten days. …”
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Image 1_G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo.tif
Published 2024“…The mechanism is poorly understood due to the lack of small animal models.</p>Methods<p>Mice were inoculated with 10<sup>7</sup> CFU of the eubiotic bacteria Lactobacillus crispatus, the dysbiotic bacteria G. vaginalis, or PBS as a negative control every 48 h for ten days. …”
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Image 4_G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo.tif
Published 2024“…The mechanism is poorly understood due to the lack of small animal models.</p>Methods<p>Mice were inoculated with 10<sup>7</sup> CFU of the eubiotic bacteria Lactobacillus crispatus, the dysbiotic bacteria G. vaginalis, or PBS as a negative control every 48 h for ten days. …”
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Sex and tissue-specificity of piRNA regulation in adult mice following perinatal lead (Pb) exposure
Published 2024“…Piwi-interacting RNAs (piRNAs) are small non-coding RNAs that associate with PIWIL proteins to induce DNA methylation. …”
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Loss of life expectancy that would result if colorectal cancer missed in 2011 had been diagnosed in 2011 (unit: years).
Published 2025Subjects: “…screening significantly decreased…”
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Estimated detected and non-detected colorectal cancer rates and their clinical stages based on colorectal cancer screening in Minamisoma City in 2011.
Published 2025Subjects: “…screening significantly decreased…”