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Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection?
منشور في 2021"…The Renin-Angiotensin System (RAS) is activated in type 2 diabetes (T2D); therefore, the aim of this study was to determine if hypoglycaemia-induced stress in T2D would potentiate serum NRP1(sNRP1) levels, reflecting an increased risk for SARS-CoV-2 infection.…"
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HbA1c over 8.5% is not predictive of increased infection rate following penile prosthesis implant surgery in diabetic patients with erectile dysfunction
منشور في 2021"…<p dir="ltr">Diabetes mellitus is associated with increased risk of erectile dysfunction. Penile prosthesis implantation is an efficient therapeutic option for erectile dysfunction, but not without risk, as infection remains a prominent concern. …"
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Strategies to manage hepatitis C virus infection disease burden – volume 3
منشور في 2015"…Increasing levels of diagnosis and treatment, in combination with improved treatment efficacy, were critical for achieving substantial reductions in disease burden. …"
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Emtricitabine/rilpivirine/tenofovir disoproxil fumarate for the treatment of HIV-1 infection in adults
منشور في 2015"…Results from two phase 3 randomized double blind trials (ECHO and THRIVE) showed that rilpivirine is non-inferior to efavirenz in suppressing viral load below 50 copies/mL in anti-retroviral therapy (ART) naïve human immunodeficiency virus (HIV) infected patients. In addition, psychiatric disturbances, rash and increase in lipid levels occurred less frequently with rilpivirine when compared to efavirenz. …"
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Risk Factors for Post-Cesarean, Surgical Site Infections in a Multi-Ethnic Population of Qatar
منشور في 2024"…SSIs not only increase patients’ morbidity and mortality rates, but also lay a huge economic burden. …"
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Demographic characteristics and clinical and laboratory features of patients with Clostridiodes difficile infection: A retrospective study in Qatar
منشور في 2025"…Increased C-reactive protein levels were the most frequently observed laboratory findings. …"
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Vulnerabilities of the SARS-CoV-2 Virus to Proteotoxicity—Opportunity for Repurposed Chemotherapy of COVID-19 Infection
منشور في 2020"…A strategy for improved drug therapy is to increase levels of endogenous reactive metabolites for selective toxicity to SARS-CoV-2 by preferential damage to the viral proteome. …"
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Vitamin D Association With Macrophage-Derived Cytokines in Polycystic Ovary Syndrome: An Enhanced Risk of COVID-19 Infection?
منشور في 2021"…</p><h3>Conclusion</h3><p dir="ltr">Basal macrophage activation was higher in PCOS with macrophage changes related with increased infection risk associating with vitamin D; all changes were BMI dependent, suggesting that obese PCOS with vitamin D deficiency may be at greater risk of more severe COVID-19 infection, but that it is obesity-related rather than an independent PCOS factor.…"
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Stress induced immunomodulation and the risk of infections during major sporting events: Implications for the FIFA World Cup 2022
منشور في 2023"…Evidence has shown that psychological stress can modulate the immune system as the neurotransmitters released by the sympathetic fibers descending from the brain to the lymphoid tissues bind some receptors on the surface of white blood cells and alter their function, hence, resulting in immunosuppression and subsequently increasing the susceptibility to infections. However, a major interindividual variability in stress-mediated immune responses exist particularly due to variability in stress-induced sympathetic nervous system activation among different people. …"
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Mortality and associated risk factors of COVID-19 infection in dialysis patients in Qatar: A nationwide cohort study
منشور في 2023"…We studied the mortality and associated risks of COVID-19 infection in dialysis patients in the state of Qatar. …"
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Rapid separation of very low concentrations of bacteria from blood
منشور في 2017"…A rapid and accurate diagnosis of the species and antibiotic resistance of bacteria in septic blood is vital to increase survival rates of patients with bloodstream infections, particularly those with carbapenem-resistant enterobacteriaceae (CRE) infections. …"
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CFD Analyses: The Effect of Pressure Suction and Airflow Velocity on Coronavirus Dispersal
منشور في 2021"…Air transmission from these sites to adjacent regions is a possibility in the scenario studied, increasing the likelihood of the virus spreading from these locations and infecting people in the surrounding areas. …"
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Eradication of hepatitis C virus infection in kidney transplant recipients using direct‐acting antiviral therapy: Qatar experience
منشور في 2020"…In the pre-direct-acting antiviral (DAA) era, treatment of HCV infection was associated with low response rates, poor tolerance, and increased risk of allograft rejection. …"
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Spatial modelling of contribution of individual level risk factors for mortality from Middle East respiratory syndrome coronavirus in the Arabian Peninsula
منشور في 2017"…The odds of dying from the disease was found to increase as age increased beyond 25 years and was much higher for individuals with any underlying comorbidities.…"
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Identification of macrophage activation-related biomarkers in obese type 2 diabetes that may be indicative of enhanced respiratory risk in COVID-19
منشور في 2021"…These differences could potentially predispose diabetic individuals to increased infection severity complicated by ARDS. </p><p> </p><p>Clinical trial reg. no: NCT03102801; registration date April 6, 2017.…"
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Airflow dynamics in an emergency department: A CFD simulation study to analyse COVID-19 dispersion
منشور في 2021"…The analysis revealed that three critical areas of the emergency department, namely overnight patient beds, operating rooms, and resuscitation rooms, had significantly higher air velocity, dispersion, and mixing levels than the rest of the department's spaces. According to the two scenarios examined, the possibility of air transmission from these locations to neighboring areas becomes apparent, increasing the likelihood of transmitting the virus from these locations and infecting people in the adjacent areas, including patients and health care providers. …"
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Molecular pattern of acquiring upper respiratory infection
منشور في 2026"…Among the key factors influencing the seasonality of these infections, variations in temperature and absolute humidity are critical elements driving the increase in respiratory virus infections, particularly during the winter months. …"