Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance by Ajaz A. Bhat (12984701)

Polysulfone/halloysite composite membranes with low fouling properties and enhanced compaction resistance by Nagla Kamal (17092960)

“…SEM images, pore size, and porosity estimations indicated that the incorporation of low to medium Hal loadings resulted in PSF/Hal membranes with smaller surface pore size, lower porosity, and thicker top skin layer due to the strong interfacial interactions between Hal and PSF matrix. …”

Rapid separation of very low concentrations of bacteria from blood by Buchanan, Clara M.

“…A rapid and accurate diagnosis of the species and antibiotic resistance of bacteria in septic blood is vital to increase survival rates of patients with bloodstream infections, particularly those with carbapenem-resistant enterobacteriaceae (CRE) infections. …”
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Reversal of Insulin Resistance in Overweight and Obese Subjects by trans-Resveratrol and Hesperetin Combination—Link to Dysglycemia, Blood Pressure, Dyslipidemia, and Low-Grade Inf... by Naila Rabbani (291722)

“…These correlations were not present with placebo. tRES-HESP decreased low-grade inflammation, characterized by decreased expression of CCL2, COX-2, IL-8, and RAGE. …”

Differences in protein expression, at the basal state and at 2 h of insulin infusion, in muscle biopsies from healthy Arab men with high or low insulin sensitivity measured by hype... by Ilham Bettahi (363910)

“…Additionally, we show differences in protein levels from skeletal muscle in low and high insulin sensitivity groups. Therefore, these differences may represent early events for the development of insulin resistance, pre-diabetes, and type 2 diabetes.…”

Therapeutic Potential of Plant Phenolic Acids in the Treatment of Cancer by Mariam Abotaleb (18808261)

“…In addition, there are increasing concerns about drug resistance. In the continuous search for safer and more effective treatments, plant-derived natural compounds are of major interest. …”

Low-level amikacin resistance induced by AAC(6′)-Ib and AAC(6′)-Ib-cr in extended-spectrum β-lactamase (ESBL)-producing Enterobacterales isolated from urine in children by Hassan Al, Mana

“…Over the past few years, however, amikacin has been increasingly used to treat urinary tract infections (UTIs) in children caused by Enterobacterales producing extended-spectrum β-lactamases (ESBLs), given the low resistance rates to this agent among ESBL-producing uropathogens worldwide. …”
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TRPV2: A Cancer Biomarker and Potential Therapeutic Target by Kodappully S. Siveen (4246150)

“…In prostate cancer, TRPV2 overexpression was associated with the castration-resistant phenotype and metastasis. Loss or inactivation of TRPV2 promoted glioblastoma cell proliferation and increased resistance to CD95-induced apoptotic cell death. …”

Epigenetic and breast cancer therapy: Promising diagnostic and therapeutic applications by Gulab Sher (12984698)

“…<p dir="ltr">The global burden of breast cancer (BC) is increasing significantly. This trend is caused by several factors such as late diagnosis, limited treatment options for certain BC subtypes, drug resistance which all lead to poor clinical outcomes. …”

Surveillance of antimicrobial resistance in Lebanese hospitals by Mokhbat, Jacques

“…Antimicrobial resistance increases healthcare costs substantially in many countries, including Lebanon. …”
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P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis by Milane, Aline

“…We observed an increased P-gp expression (1.5-fold) in presymptomatic mSOD1 mice compared to wild-type controls. …”
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Prophylactic and therapeutic antibiotic patterns of lebanese dentists for the management of dentoalveolar abscesses by Mokhbat, J.

“…The main prescribed antibiotic was amoxicillin.This study showed that dentists often did not follow the current prophylactic and therapeutic antibiotic prescription guidelines.Antibiotics prescriptions in dentistry will be more pertinent, leading to a decrease in inadequacy of prescriptions, microbial resistance, and the development of multiresistant germs against antibiotics…”
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Emerging Glycation-Based Therapeutics—Glyoxalase 1 Inducers and Glyoxalase 1 Inhibitors by Naila Rabbani (291722)

“…Increased MG glycation produces inactivation and misfolding of proteins, cell dysfunction, activation of the unfolded protein response, and related low-grade inflammation. …”

Strategies for the production of long-acting therapeutics and efficient drug delivery for cancer treatment by Alanod D. AlQahtani (18805930)

“…These two techniques improve stability, reduce immunogenicity, and increase drug resistance to proteases. These factors lead to the reduction of injection frequency which increases patient compliance and improve quality of life. …”

The effects of daucus carota extracts on different body functions, inflammation, induced gastric ulcer in rats and bacterial growth. (c2005) by Abdallah, Katia Wehbe

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Effect of methanolic extract of Quercus infectoria bark on blood lipid profile, glycemia, inflammation, platelet aggregation, ulcer and bacterial activity. (c2005) by Khouzami, Lara

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FoxP3⁺ T regulatory cells in cancer: Prognostic biomarkers and therapeutic targets by Reem Saleh (3513056)

“…Despite the success of immunotherapy, including the use of immune checkpoint inhibitors, a significant proportion of patients show low response rates as a result of primary or acquired resistance against therapy. …”

The changing landscape in the treatment of metastatic castration-resistant prostate cancer by El Amm, Joelle

“…The past few years have brought increasing advances in the therapeutic management of metastatic castration-resistant prostate cancer with the approval of several agents, including vaccine therapy with sipuleucel-T, second-line chemotherapy with cabazitaxel, the bone-targeted pharmaceutical denosumab, and the novel antiandrogen therapy abiraterone acetate. …”
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Glycation in Alzheimer’s Disease and Type 2 Diabetes: The Prospect of Dual Drug Approaches for Therapeutic Interventions by Sama Ayoub (15430987)

“…<p dir="ltr">As global life expectancy increases, the prevalence of neurodegenerative diseases like Alzheimer’s disease (AD) continues to rise. …”

Metabolic signature of obesity-associated insulin resistance and type 2 diabetes by Haya Al-Sulaiti (5449256)

“…</p><h3>Conclusion</h3><p dir="ltr">This pilot data has identified phospholipid metabolites as potential novel biomarkers of obesity-associated insulin sensitivity and confirmed the association of known metabolites with increased risk of obesity-associated insulin resistance, with possible diagnostic and therapeutic applications. …”