Characterizing the Effect of Arginine Deprivation on Autophagic Response in Breast Cancer cells حسب Haidar, Fatemah

"…Residual ASS1 tumor expression corelated with increased metastasis and decreased survival in patient luminal A, Her2+ and triple-negative breast cancer. …"
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Investigating the Therapeutic Effects of Small Molecule Imipridones In Pediatric Neuroblastoma حسب El Soussi, Sarra

"…Our findings demonstrate an important multi-target effect of imipridones that may yield added therapeutic benefits in treating this devastating cancer.…"
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P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis حسب Milane, Aline

"…Consistent with this, P-gp function was also increased by 1.5-fold and riluzole brain disposition was decreased by 1.7-fold in mSOD1 mice. …"
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Optimizing clopidogrel dose response حسب Saab, Yolande B.

"…Results The study results show that all patients under clopidogrel treatment, whose genotypes are different from *1*1, and concomitantly taking other drugs metabolized by CYP2C19 require clopidogrel dose adjustment. To get a therapeutic effect and avoid adverse drug reactions, therapeutic dose of 75 mg clopidogrel, for example, should be lowered to 6 mg or increased to 215 mg in patients with different genotypes. …"
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Skin responses to fractional photothermolysis حسب Tannous, Zeina

"…Background and Objective Fractional photothermolysis (FP) is a new concept using arrays of microscopic thermal damage patterns to stimulate a therapeutic response. We analyzed epidermal and dermal response to FP with the aim of correlating histological and clinical response. …"
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Role of the gut microbiota in the pathogenesis of coeliac disease and potential therapeutic implications حسب Anthony K. Akobeng (7713470)

"…Dysbiotic microbiota may lead to a dysregulated immune response that may contribute to the pathogenesis of coeliac disease. …"

Emerging Glycation-Based Therapeutics—Glyoxalase 1 Inducers and Glyoxalase 1 Inhibitors حسب Naila Rabbani (291722)

"…Increased MG glycation produces inactivation and misfolding of proteins, cell dysfunction, activation of the unfolded protein response, and related low-grade inflammation. …"

The therapeutic potential of matcha tea: A critical review on human and animal studies حسب Sara Sokary (17337724)

Decoding the Therapeutic Potential of [HuArgI (Co)-PEG5000] Arginase Treatment حسب Zeineddine, Mira

"…Moreover, our study results lay the groundwork for the creation of innovative combination treatments that specifically target different facets of cancer cell behavior, offering patients with breast cancer better prognoses and increased therapeutic efficacy.…"
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FoxP3⁺ T regulatory cells in cancer: Prognostic biomarkers and therapeutic targets حسب Reem Saleh (3513056)

"…They maintain immune homeostasis and inhibit immune responses in various diseases, including cancer. Proportions of Tregs in the peripheral blood of some cancer patients increase by approximately two-fold, compared to those in healthy individuals. …"

The Protective Effects of Daucus carota L. ssp. carota and Cannabis sativa L. Extracts against Cisplatin Induced Nephrotoxicity in Animal Models حسب Al Toufaily, Sahar

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Ultrasound-responsive Nanocarriers in Cancer Treatment: a review حسب Awad, Nahid S.

"…Using smart nanocarriers, the rate of release of the entrapped therapeutic(s) can be increased, and greater exposure of the tumor cells to the therapeutics can be achieved when the nanocarriers are exposed to certain internally (enzymes, pH and temperature) or externally applied (light, magnetic field, and ultrasound) stimuli that trigger the release of their load in a safe and controlled manner, spatially and temporally. …"
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The Obesity Paradox in Cancer, Tumor Immunology, and Immunotherapy: Potential Therapeutic Implications in Triple Negative Breast Cancer حسب Adviti Naik (673163)

Recombinant Adeno-Associated Virus-Mediated In Utero Gene Transfer Gives Therapeutic Transgene Expression in the Sheep حسب Abi Nader, Khalil

"…This is the first study to show therapeutic long-term hFIX transgene expression after in utero gene transfer in a large animal model.…"
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Acoustically activated release of estrone-targeted liposomes used for breast cancer treatment حسب Mohammad, Najla

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Chronic reduction of store operated Ca²⁺ entry is viable therapeutically but is associated with cardiovascular complications حسب Fang Yu (156838)

"…Given its central role in immune cell activation, SOCE has been a therapeutic target for autoimmune and inflammatory diseases. …"

Microbial Dysbiosis Tunes the Immune Response Towards Allergic Disease Outcomes حسب Tracy Augustine (14149932)

"…<p>The hygiene hypothesis has been popularized as an explanation for the rapid increase in allergic disease observed over the past 50 years. …"

Tolfenamic Acid Derivatives: A New Class of Transcriptional Modulators with Potential Therapeutic Applications for Alzheimer’s Disease and Related Disorders حسب Jaunetta Hill (18255631)

"…Specific levels of SP1-driven genes and AD biomarkers such as amyloid precursor protein (APP) and Tau proteins were also decreased as part of this targeted systemic response. …"

Editorial: Dynamic Biomarkers of Response to Anti-Immune Checkpoint Inhibitors in Cancer حسب Said Dermime (79420)

"…One promising emerging approach is to focus on dynamic biomarkers, which would allow, when tested in the patient early after exposition to the therapeutic agents, to identify those patients presenting an immune response failure. …"

Evaluation of cationic channel TRPV2 as a novel biomarker and therapeutic target in Leukemia-Implications concerning the resolution of pulmonary inflammation حسب Kodappully S. Siveen (4246150)

"…Challenging lung airway epithelial cells (AECs) with LBCs decreased (by more than 50%) transepithelial resistance (TER) denoting barrier function alteration. …"