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Epigenetic and breast cancer therapy: Promising diagnostic and therapeutic applications
Published 2022“…Nevertheless, it promises to provide novel insight needed for utilizing these alterations as potential diagnostic, prognostic markers, predict treatment efficacy, as well as therapeutic agents. This highlights the importance of continuing research development to further advance the existing knowledge on epigenetics and BC carcinogenesis to overcome the current challenges. …”
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Recent Advances in Nanoparticle-Based Co-Delivery Systems for Cancer Therapy
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Anticancer and antioxidant effects of tragopogon porrifolius extract. (c2011)
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A potential therapeutic agent for sickle cell anaemia
Published 2016“…They also found increased levels of ROS that were associated with decreased levels of antioxidant enzymes and their co-factors.…”
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iPSCs derived from insulin resistant offspring of type 2 diabetic patients show increased oxidative stress and lactate secretion
Published 2022“…Therefore, in this study, we aimed to investigate the genetic perturbations associated with insulin resistance (IR) in the offspring of T2D parents using patient-specific iPSCs.…”
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FoxP3<sup>+</sup> T regulatory cells in cancer: Prognostic biomarkers and therapeutic targets
Published 2020“…Despite the success of immunotherapy, including the use of immune checkpoint inhibitors, a significant proportion of patients show low response rates as a result of primary or acquired resistance against therapy. Some of the mechanisms which underlie the development of therapy resistance are associated with Treg suppressive function. …”
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Cancer cell plasticity: from cellular, molecular, and genetic mechanisms to tumor heterogeneity and drug resistance
Published 2024“…Despite significant advancements in targeted therapies, cancer cell adaptability and subsequent therapy-induced resistance remain persistent obstacles in achieving consistent, successful cancer treatment outcomes. …”
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Emerging therapies in multiple myeloma
Published 2015“…However, despite the increased effectiveness of the first-line agents, the majority of patients will eventually relapse and become drug resistant. …”
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Natural products as chemo-radiation therapy sensitizers in cancers
Published 2022“…Surgery, chemotherapy (CT), and/or radiation therapy (RT) are the treatment of choice for most advanced tumors. …”
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Decoding the Therapeutic Potential of [HuArgI (Co)-PEG5000] Arginase Treatment
Published 2023“…Moreover, our study results lay the groundwork for the creation of innovative combination treatments that specifically target different facets of cancer cell behavior, offering patients with breast cancer better prognoses and increased therapeutic efficacy.…”
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The changing landscape in the treatment of metastatic castration-resistant prostate cancer
Published 2012“…The past few years have brought increasing advances in the therapeutic management of metastatic castration-resistant prostate cancer with the approval of several agents, including vaccine therapy with sipuleucel-T, second-line chemotherapy with cabazitaxel, the bone-targeted pharmaceutical denosumab, and the novel antiandrogen therapy abiraterone acetate. …”
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Cisplatin based therapy: the role of the mitogen activated protein kinase signaling pathway
Published 2018“…A Combination of cisplatin with other drugs is an approach to overcome drug resistance and reduce toxicity. The combination therapy also results in increased sensitivity of cisplatin towards cancer cells. …”
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