Image_2_Reelin Can Modulate Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Neurons via the Canonical Pathway.TIF by Leigh Dairaghi (5591222)

“…Chronic treatment of nasal explants with CR-50, an antibody known to interfere with Reelin homopolymerization and Dab1 phosphorylation, decreased the distance GnRH neurons and OECs migrated. …”

Integrated analysis of promoter mutation, methylation and expression of <i>AKT1</i> gene in Chinese breast cancer patients by Jianfu Heng (3842491)

“…And a trend of decrease in expression level (<i>P</i> = 0.0624) of <i>AKT1</i> in the ER negative subtype was observed, which is significantly decreased in basal-like breast tumor (<i>P</i> = 0.0328).…”

Evaluation of Epicardial Adipose Tissue by Echocardiography and Its Correlation with Aortic Velocity Propagation and Carotid Intima-Media Thickness in Patients of Type 2 Diabetes M... by RAMAZAN ASOĞLU (10365404)

“…On the other hand, aortic velocity propagation was decreased in the non-insulin dependent diabetes mellitus group compared to non-diabetic patients (EFT; 8.43 ± 1.68 versus 6.36 ± 2.21 mm, p < 0.001; CIMT; 0.92 ± 0.24 versus 0.58 ± 0.18 mm, p < 0.001; and AVP; 28.20 ± 16.02 versus 58.10 ± 17.50, p < 0.01, respectively). …”

Tacrolimus and MPA can inhibit signaling pathway activation in whole-blood samples. by Nynke M. Kannegieter (3697594)

“…(Data are plotted as the mean ±SEM; n = 5) *) p < 0.05; **) p < 0.01; ***) p < 0.001.…”

Bifurcation points led to multiple spike patterns that persisted across multiple amplitudes. by J. Vincent Toups (127111)

“…We used the value <i>t_ISI</i> = 3 ms to detect the events using the interval method and the value <i>t_ROC</i> = 0.50 to find and merge common events. …”

Impairment of RPA foci formation and the DNA damage checkpoint in CBP and p300 depleted cells. by Hideaki Ogiwara (18358)

“…Whole cell extracts were subjected to immunoblot analysis. (<b>B, C</b>) Decreased DSB-induced chromatin binding of RPA proteins. …”

Effect of BM pretreatment on P-gp level. by Rajbir Singh (451210)

“…BM represent rats pretreated with BM (31 mg/kg/day) for 7 days and control represents rats received same volume of vehicle Values are expressed as mean ± S.D. all results are from 3 independent experiments with similar results; * indicates significant difference in BM pretreated rats compared to vehicle treated rats with P value <0.05. …”

Air Pollutant Emission Inventory of Waste-to-Energy Plants in China and Prediction by the Artificial Neural Network Approach by Wenchao Ma (3393713)

“…The WTE capacity increased by 150% from 2015 to 2020, while the total emission of PM, SO₂, CO, dioxins, Hg, and Sb + As + Pb + Cr + Co + Cu + Mn + Ni decreased by 42.46–88.24%. The artificial neural network models were established to predict WTE capacity and FGP EIs in the city level, with the mean square errors ranging from 0.003 to 0.19 within the model validation limits. …”

TL induces oxidative stress in p53-Deficient HCT116 cells. by Ajay Kumar (192967)

“…(B,C,D) Relative protein quantity normalized to PCNA is presented (**p<0.01, n = 3). (E) TL decreases glutathione content. …”

Data_Sheet_2_Identification of Trypanosoma cruzi Polyamine Transport Inhibitors by Computational Drug Repurposing.PDF by Chantal Reigada (3844975)

“…Three of them, promazine, chlorpromazine, and clomipramine, showed to be effective inhibitors of putrescine uptake, and also revealed a high trypanocidal activity against T. cruzi amastigotes (IC₅₀ values of 3.8, 1.9, and 2.9 μM, respectively) and trypomastigotes (IC₅₀ values of 3.4, 2.7, and 1.3 μM, respectively) while in epimastigotes the IC₅₀ were significantly higher (34.7, 41.4, and 39.7 μM, respectively). …”

Data_Sheet_1_Identification of Trypanosoma cruzi Polyamine Transport Inhibitors by Computational Drug Repurposing.PDF by Chantal Reigada (3844975)

“…Three of them, promazine, chlorpromazine, and clomipramine, showed to be effective inhibitors of putrescine uptake, and also revealed a high trypanocidal activity against T. cruzi amastigotes (IC₅₀ values of 3.8, 1.9, and 2.9 μM, respectively) and trypomastigotes (IC₅₀ values of 3.4, 2.7, and 1.3 μM, respectively) while in epimastigotes the IC₅₀ were significantly higher (34.7, 41.4, and 39.7 μM, respectively). …”

Age associated arrhythmicity is dependent on <i>ena</i> function. by Carolina Rezával (270700)

“…Quantification of RNA levels showed significant changes in <i>ena^rev</i> homozygous (* <i>p</i><0.05) whereas a minor (non significant) decrease was seen in <i>ena^rev/+</i> heterozygous when compared to the <i>y w</i> control line. …”

Data_Sheet_1_Plasminogen and the Plasminogen Receptor, Plg-RKT, Regulate Macrophage Phenotypic, and Functional Changes.PDF by Juliana P. Vago (6892781)

Narrative, Literature and the Experience of Illness, University of Pittsburgh by Post Discipline Admin (12858854)

Highly Symmetric Group 13 Metal−Phosphinato Complexes:  Multinuclear NMR (²⁷Al, ³¹P, ⁷¹Ga) Determination of Stability Constants at Low pH by Mark P. Lowe (1870264)

“…The formation constants for In³⁺ (log β₂ ≥ 5.4), Ga³⁺ (log β₂ = 4.24), and Al³⁺ (log β₁ = 0.93, log β₂ = 3.45) decrease by an order of magnitude as the group is ascended, consistent with increasing steric interactions of the phenyl groups as the two trisphosphinate ligands are crowded together in order to coordinate the smaller metal ions. …”

DHX29 functions an RNA co-sensor and interacts with MDA5 for enhanced RNA recognition and type I IFN signaling. by Qingyuan Zhu (121225)

“…<p>(<b>A</b>) Schematic of DHX29 truncated forms (<i>top panel</i>). 293T cells were transfected with <i>Flag-MDA5</i> and full-length <i>HA-DHX29</i> (<i>FL-DHX29</i>), <i>HA-DHX29a</i>, <i>HA-DHX29b</i>, <i>HA-DHX29c</i>, or <i>HA-DHX29d</i> plasmids. …”

<i>klf4</i> is required for the maintenance of the <i>egc</i>^<i>+</i><i>/meg-1</i>^<i>+</i><i>/zfp-1-1</i>^<i>+</i> TRL. by Lu Zhao (296389)

“…Numbers at bottom left represent the fraction of parasites displaying the observed phenotype. (F) FISH depicting a modest decrease in <i>tsp-2</i>⁺ cell number following <i>klf4</i> RNAi. …”

Data Sheet 1_How low can you go? Antibiotic use in Swedish dogs with gastroenteritis.pdf by Ditte Ljungquist (20446670)

“…Concurrently, the annual all-cause mortality decreased for all CGE consultations. Higher levels of antibiotic use were seen in hospitalized CGE (21.7% compared to 2.1% for non-hospitalized CGE, OR 13.1, 95% CI: 12.3–14.0, p < 0.001) and hemorrhagic diarrhetic CGE (21.0% compared to 5.5% for non-hemorrhagic diarrhetic CGE, OR 4.6, 95% CI: 4.2–4.9, p < 0.001).…”

Data Sheet 3_How low can you go? Antibiotic use in Swedish dogs with gastroenteritis.pdf by Ditte Ljungquist (20446670)

“…Concurrently, the annual all-cause mortality decreased for all CGE consultations. Higher levels of antibiotic use were seen in hospitalized CGE (21.7% compared to 2.1% for non-hospitalized CGE, OR 13.1, 95% CI: 12.3–14.0, p < 0.001) and hemorrhagic diarrhetic CGE (21.0% compared to 5.5% for non-hemorrhagic diarrhetic CGE, OR 4.6, 95% CI: 4.2–4.9, p < 0.001).…”

Data Sheet 2_How low can you go? Antibiotic use in Swedish dogs with gastroenteritis.pdf by Ditte Ljungquist (20446670)

“…Concurrently, the annual all-cause mortality decreased for all CGE consultations. Higher levels of antibiotic use were seen in hospitalized CGE (21.7% compared to 2.1% for non-hospitalized CGE, OR 13.1, 95% CI: 12.3–14.0, p < 0.001) and hemorrhagic diarrhetic CGE (21.0% compared to 5.5% for non-hemorrhagic diarrhetic CGE, OR 4.6, 95% CI: 4.2–4.9, p < 0.001).…”